Dosage,

Route,
Name of Mechanism of Adverse Special
Frequency Indication Nursing Responsibilities
Drug Action Reactions Precautions
and
Timing

Generic: Dosage: Benzathine penicillin Penicillin G benzathine Skin rash, Hypersensitivity to Observe 10 rights of drug
is in a class of beta- is used to treat a wide anaphylaxis, cephalosporins and administration.
Penicillin G 1.2 lactam antibiotics. variety of bacterial hemolytic anemia, other beta-lactam
Benzathine MIU/vial Beta-lactams are infections. It may also Determine history of
angioedema, antibiotics, poor
bactericidal be used to prevent hypersensitivity reactions to
antibiotics. This type certain bacterial urticarial, acute renal functions.
penicillins, cephalosporins,
of antibiotic inhibits infections (such interstitial nephritis
IV and intrathecal or other allergens prior to
Brand: Route:
biosynthesis of the as rheumatic fever). initiation of drug therapy.
injection should be
Zalpen IM cell wall This medication is a
peptidoglycan during long-acting penicillin avoided.
(buttocks) Perform C&S tests prior to
the stage of active antibiotic. It works by initiation of therapy and
History of cardiac
multiplication. This stopping the growth periodically thereafter.
results in an of bacteria. decompensation,
Perform periodic renal
Classificati Frequency: osmotically unstable severe heart
Contraindications Side Effects function tests.
on cell wall, leading to disease.
Single dose lysis of the cell wall,
Drug is not for IV use. Do
Functional: every 21 subsequent Hypersensitivity to Pain, swelling,
notinject or mix with other
days destruction of the penicillins. Do not bleeding or lump at
Bacteriostatic IV solutions.
bacterial cell, and inject into or near an the injection site,
antibacterial death. artery or nerve.
nausea, vomiting Monitor patient for at least
agent
Timing: WebMD (2020) 30 minutes after
Chemical: administration.
Every 21
N,N'- days/ Report immediately to
dibenzylethyl physician the onset of an
enediamine allergic reaction. There is
great risk of severe and
prolonged reactions because
drug is absorbed so slowly.