An additive used to resist change in pH of the preparation.

 
Citric acid

Benzalkonium chloride uses 0.1-0.02% concentration for nasal and otic preparations.
False

Flavorant used to mask bitter taste.

Walnut

Sweetening agent that has relative sweetness of 30 than sucrose. → sodium cyclamate
Sweetening agent with poor stability in heating. → Aspartame
Sweetening agent that that has metallic after taste. → saccharin

Concentration of citric acid used as buffer agent.

1-3%

All are antioxidants used for oleaginous preparations, except.

ascorbic acid

Fixed oil used as solvent for antifungal ear drops.

castor oil 

Used as solvent to dissolve earwax

Xylene

All are type of fixed oils used as solvent for parenterals, except;
castor oil

Flavorant used to mask salty sweet taste.

berries and vanilla

Solvent that causes lipoidal pneumonia.

liquid paraffin

Preservative incompatible with anionic substances.

benzalkonium chloride

Solvent used for enhancing the penetration of drugs through skin.

Dimethyl suphoxide
Colorants used for non-aqueous preparation.
Lakes

Concentration of glutamic acid used as buffer agent.

1-2%

Thimerosal acts on microbes by denaturation of its enzymes.

True

Preservative used for ophthalmic preparation.

thimerosal and methyl parabens

Sorbic and Benzoic acid are antimicrobial preservatives.

False

All unused and uncoded labels and pre-printed packaging materials shall be destroyed.
True

Action of preservatives is the denaturation of enzymes by combining with thiol.

Nitromersol

Used as an alternative for glycerin

propylene glycol

Friability and hardness test → compression process

Sieve analysis → tablet granulation
Average unit weight → tablet coating
Viscosity → ointments
Specific gravity → liquid processing

Flocculating agent with a linear branched-chain molecule forming a gel-like network within the system.
→ Polymeric flocculating agent
A wetting agent that provides a protective coating of particles. → Hydrophobic colloids
Inorganic agent used to decrease the electrokinetic potential in colloidal dispersions. → electrolytes
Emulsifying agent for parenteral emulsions. → Non-ionic
Emulsifying agent that can be absorbed at the oil/water interface. → Finely divided solids

more soluble in cold than hot water → methylcellulose,

clear solution in hot and cold water → carmellose sodium,
will not form gel on heating → hydroxyethylcellulose,
Stabilize the product against flocculating effects of added electrolytes → microcrystalline cellulose

A semi-synthetic polysaccharide used as emulsifying agent

Carmellose Na
Also used as wetting agent → sulphonated compound,
Incompatible with polyvalent cations → alkali metals and ammonium soaps,
Used in formulation of calamine lotion → calcium salts,
Use in cosmetics → triethanolamine

Surfactant used for parenteral preparations.

Lecithin

gelatin → opacifiers,
castor oil → plasticizer,
silica → sorbents,
beeswax → glossant,
metallic stearates → anti-adherent,
hydroxylpropyl cellulose → film former

not softened by the frictional forces of compression due to its high melting point → lactose
forms hard tablets but with good disintegration → microcrystalline cellulose
requires more lubricant and glidants for water-sensitive drugs → Sugar alcohol
water insoluble and hydrophilic → dicalcium phosphate dehydrate

Lubricants are added at the first step of compression to prevent the reduce tablet strength that leads to
decrease disintegration and dissolution rate.
False

Emulsifying agent that is also use as disinfectant and preservative.

Cationic

Possess unpleasant taste → polysorbates,

Self-emulsifyung with anionic → glycol,
For W/O preparation → sorbitan
Salted out by addition of high concentration of electrolytes → fatty alcohol polyglycol

form tablets that are brittle and hard → sucrose

Gives a moderate hardness tablet → mannitol
form tablets that are brittle and soft → starch

Surfactants used for oral preparation.

Sorbitan esters