PŬĂƌLJŽƚ ŚƺĐƌĞůĞƌĚĞŚƺĐƌĞnjĂƌŦŝůĞĕĞŬŝƌĚĞŬnjĂƌŦĂƌĂƐŦŶĚĂŬĂůĂŶďƂůŐĞƐŝƚŽƉůĂnjŵĂŝůĞĚŽůƵĚƵƌ͘ Sitoplazma;

LJĂƌŦĂŬŦƔŬĂŶƐŦǀŦƐĂůŬŦƐŦŵ͕ŽƌŐĂŶĞůůĞƌǀĞŚƺĐƌĞŝƐŬĞůĞƚĞůĞŵĂŶůĂƌŦŶŦŝĕĞƌŝƌ͘^ŝƚŽƉůĂnjŵĂŶŦŶйϳϬ- йϵϬ͛Ŧ
OGM
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ƐƵĚƵƌ͘LJƌŦĐĂŝĕĞƌŝƐŝŶĚĞŵŝŶĞƌĂůůĞƌ͕ƚƵnjůĂƌ͕ŐĂnjůĂƌ͕ƉƌŽƚĞŝŶůĞƌ͕ŬĂƌďŽŶŚŝĚƌĂƚůĂƌ͕LJĂŒůĂƌ͕ĞŶnjŝŵůĞƌ͕
ŚŽƌŵŽŶůĂƌ͕ǀŝƚĂŵŝŶůĞƌ͕ďŽƔĂůƚŦŵĂƚŦŬůĂƌŦ͕dW͕ŶƺŬůĞŽƚŝƚůĞƌǀĞZEďƵůƵŶƵƌ͘
MATERYAL
Endoplazmik Retikulum ORTAÖĞRETİM GENEL MÜDÜRLÜĞÜ

,ƺĐƌĞKƌŐĂŶĞůůĞƌŝ ,ƺĐƌĞnjĂƌŦŶĚĂŶďĂƔůĂLJŦƉĕĞŬŝƌĚĞŬnjĂƌŦŶĂŬĂĚĂƌƵnjĂŶĂŶŚƺĐƌĞŝĕŝŬĂŶĂůůĂƌƐŝƐƚĞŵŝĚŝƌ͘,ƺĐƌĞLJĞĚĞƐƚĞŬůŝŬ
KONU 6ý723/$=0$9(25*$1(//(5, ƐĂŒůĂŵĂ͕ŚƺĐƌĞĕĞŬŝƌĚĞŒŝŶŝŶďĞůŝƌůŝďŝƌďƂůŐĞĚĞƐĂďŝƚŬĂůŵĂƐŦ͕ĂƐŝĚŝŬ-bazik tepkimelerin birbirinden
dƺŵĐĂŶůŦůĂƌĚĂƐŝƚŽƉůĂnjŵĂŝĕĞƌŝƐŝŶĚĞ͕LJĂƔĂŵƐĂůĨĂĂůŝLJĞƚůĞƌŝŐĞƌĕĞŬůĞƔƚŝƌĞŶǀĞorganel ĂĚŦǀĞƌŝůĞŶ .RIXO
ĂLJƌŦůŵĂƐŦ͕ ŚƺĐƌĞŝĕĞƌŝƐŝŶĚĞŵĂĚĚĞůĞƌŝŶƚĂƔŦŶŵĂƐŦŶĚĂŐƂƌĞǀĂůŦƌ͘
ƂnjĞůůĞƔŵŝƔLJĂƉŦůĂƌďulunur. WƌŽŬĂƌLJŽƚŚƺĐƌĞůĞƌ͕ƐĂĚĞĐĞnjĂƌƐŦnj bir organel olan ribozoma sahiptir.
Ribozom
PŬĂƌLJŽƚŚƺĐƌĞůĞƌŝƐĞĨĂƌŬůŦŐƂƌĞǀǀĞĨŽŶŬƐŝLJŽŶůĂƌŝĕŝŶƂnjĞůůĞƔŵŝƔnjĂƌƐŦnj,
6î723/$=0$ “NDU\RWK¸FUHOHUGHK¸FUH]DU¿LOH granüllü endoplazmik retikulum, bulundurmayanlara granülsüz (düz)
bulunduranlaraƚĞŬǀĞĕŝĨƚŬĂƚůŦnjĂƌĂƐĂŚŝƉ
5LER]RPEXOXQGXUDQODUDJUDQ¸OO¸HQGRSOD]PLN
ŽƌŐĂŶĞůůĞƌŝĕĞƌŝƌ͘
£HNLUGHN]DU¿DUDV¿QGDNDODQE²OJHVLWRSOD]PDLOHGROXGXU endoplazmik retikulum denir.
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6LWRSOD]PD\DU¿DN¿ÅNDQV¿Y¿VDON¿V¿PRUJDQHOOHUYHK¸FUH HQGRSOD]PLNUHWLNXOXPGHQLU *ROJLD\J¿W¿
LVNHOHWHOHPDQODU¿Q¿L£HULU6LWRSOD]PDQ¿QÜ¿VXGXU 6LWRSOD]PD
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Ribozom
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L£HULVLQGH\DÅDPVDOIDDOL\HWOHULJHU£HNOHÅWLUHQYHRUJDQHO
gelir. WƌŽŬĂƌLJŽƚŚƺĐƌĞĚĞƌŝďŽnjŽŵůĂƌ͕ƐŝƚŽƉůĂnjŵĂĚĂƐĞƌďĞƐƚŚąůĚĞďƵůƵŶƵƌ͘ PŬĂƌLJŽƚ ŚƺĐƌĞůĞƌĚĞ
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LJƺnjĞLJŝŶĚĞ͕ŵŝƚŽŬŽŶĚƌŝǀĞƉůĂƐƚŝƚůĞƌĚĞďƵůƵŶƵƌ͘
]DUV¿]WHNYH£LIWNDWO¿]DUDVDKLSRUJDQHOOHUL£HULU SORULAR
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HQN¸£¸NYH]DUV¿]RUJDQHOOHULRODQULER]RPODU¿QGD *UDQ¸OV¸]HQGRSOD]PLNUHWLNXOXPXQJ²UHYOHUL
JHU£HNOHÅLU%¸\¸NYHN¸£¸NROPDN¸]HUHLNLDOWELULPGHQ LOHLOJLOL
PH\GDQDJHOHQ ,]DUDUO¿PROHN¸OOHUL]DUDUV¿]KDOHG²Q¸ÅW¸UPHN
5LER]RP
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3URNDU\RWK¸FUHGH ¾ Granüllü Endoplazmik Retikulum
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5LER]RPODUGD¸UHWLOHQSURWHLQOHUOHELUOLNWHK¸FUH &(9$3(
VHUEHVWKžOGH ZŝďŽnjŽŵůĂƌĚĂƺƌĞƚŝůĞŶƉƌŽƚĞŝŶůĞƌůĞďŝƌůŝŬƚĞŚƺĐƌĞĚŦƔŦŶĂǀĞƌŝůĞĐĞŬŽůĂŶƐĂůŐŦůĂƌŦŶďƺLJƺŬďŝƌŬŦƐŵŦŐƌĂŶƺůůƺ
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ŐƂŶĚĞƌŝůŝƌ͘
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VLWRSOD]PDGD ¾ Granülsüz Endoplazmik Retikulum
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HWNLOHULQLQ\RNHGLOPHVLQLVD½ODU.DUDFL½HUK¸FUHOHULQGH
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ƉĂƌĕĂůĂŶŵĂƐŦŶŦƐĂŒůĂƌ͘
Granülsüz endoplazmik retikulumun görevleri
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glikoprotein ve lipoprotein ŐŝďŝŵĂĚĚĞůĞƌŝŶƺƌĞƚŝŵŝǀĞƐĂůŐŦůĂŶŵĂƐŦŶĚĂŶƐŽƌƵŵůƵĚƵƌ͘ DĂĚĚĞůĞƌŝŶŚƺĐƌĞ
ǀĞƌŝůĞŶůĞƌĚĞŶŚĂŶŐŝůĞƌŝĚŽŒƌƵĚƵƌ͍
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