1.

Hyoscine N-Butylbromide plus Ranitidine plus Metoclopramide

DOSAGE, MECHANIS
DRUG CONTRAINDICATION NURSING
ROUTE, M OF INDICATIONS ADVERSE EFFECTS
NAME S RESPONSIBILITIES
FREQUENCY ACTION
Hyoscine N- Ordered: The mechanism  Spasm in the Myasthenia gravies,  Constipation  Take this drug 30
Butylbromide Hyoscine N- of action of genitourinary megacolon,  Decreased minutes to 1 hour
Butylbromide Buscopan is tract hypersensitivity to drug sweating before meals
Brand Name: 10 mg that it blocks  Spasm in the contents, narrow angle  Mouth, skin, eye  Buscopan will
Buscopan the muscarinic gastrointestina glaucoma, prostate dryness potentiate the effect
Availability: receptors found l tract hypertrophy with urinary  Blurred feeling of alcohol and other
Drug Ampule 20mg on the smooth  Spasm in the retention, mechanical  Bloating CNS depressants.
classification: muscle walls biliary tract stenosis in the GI tract,  Dysuria  Do not take
Antispasmodi which means  Colic tachycardia. antacids and
 Nausea or
c its blocks the antidiarrheal 2 to 3
vomiting
action of Drug Interaction hours prior to
 Lightheadedness
acetylcholine  Potassium chloride raking this drug.
on the receptors  Headache  It is not necessary
 Metoclopramide
found within  Weakness to take
 MAO inhibitors
the smooth  Beta-agonists the medication if
muscle of the  Anticholinergics you are not in pain.
gastrointestinal  Antacids  Avoid driving or
and urinary operating
 Droperidol
tract and thus machinery after
reduces the parenteral dose.
spasms and
contractions.
This relaxes the
muscle and
thus reduced
the pain from
the cramps and
spasms.
 DOSAGE,
MECHANISM CONTRAINDICATION ADVERSE NURSING
DRUG NAME ROUTE, INDICATIONS
OF ACTION S EFFECTS RESPONSIBILITIES
FREQUENCY
Ranitidine Ordered: Ampule Potent anti-ulcer Short-term Safe use during pregnancy CNS: Headache, Assessment & Drug
50mg drug that treatment of active (category B) or lactation is malaise, dizziness, Effects
Brand Name: competitively and duodenal ulcer; not established. somnolence,  Potential toxicity
Zantac, Zantac Availability: reversibly inhibits maintenance insomnia, vertigo, results from
EFFERdose, IV  50 mg q6–8h; histamine action therapy for mental confusion, decreased clearance
Zantac GELdose, 150–300 mg/24 h at H2-receptor duodenal ulcer agitation, (elimination) and
Zantac-75 by continuous sites on parietal patient after depression, therefore prolonged
infusion cells, thus healing of acute hallucinations in action; greatest in the
Drug blocking gastric ulcer; treatment of older adults. older adult patients
Classification: acid secretion. gastroesophageal CV: Bradycardia or those with hepatic
gastrointestinal Indirectly reduces reflux disease; (with rapid IV or renal dysfunction.
agent; pepsin secretion short-term push).  Be alert for early
antisecretory (h2- but appears to treatment of GI: Constipation, signs of hepatoxicity
receptor have minimal active, benign nausea, abdominal (though low and
antagonist) effect on fasting gastric ulcer; pain, diarrhea. thought to be a
and postprandial treatment of Skin: Rash. hypersensitivity
serum gastrin pathologic GI Hematologic: reaction): jaundice
concentrations or hypersecretory Reversible decrease (dark urine, pruritus,
secretion of conditions (e.g., in WBC count, yellow sclera and
gastric intrinsic Zollinger-Ellison thrombocytopenia. skin), elevated
factor or mucus. syndrome, Body Whole: transaminases
systemic Hypersensitivity (especially ALT) and
mastocytosis, and reactions, LDH.
postoperative anaphylaxis (rare).  Long-term therapy
hypersecretion); may lead to vitamin
heartburn. B12 deficiency.

DRUG NAME DOSAGE, MECHANISM INDICATIONS CONTRAINDICATIONS ADVERSE NURSING

ROUTE, OF ACTION EFFECTS RESPONSIBILITIES
 FREQUENCY
Metoclopramide Ordered: Ampule Stimulates  Relief of Concentrations CNS: restlessness, Before:
10 mg motility of upper symptoms of  Allergy to drowsiness, fatigue,  Observe 15 rights in
Brand name: GI tract without acute and metoclopramide lassitude, insomnia, drugs administration
Reglan, Maxolon stimulating recurrent  GI hemorrhage extrapyramidal  Assess for allergy to
gastric, biliary or diabetic  Mechanical obstruction reactions, metoclopramide
Drug pancreatic gastroparesis or perforation parkinsonism-like  Assess for other
classification: secretions;  Short-term  Pheochromocytoma reactions, akathisia, concentrations
Pharmacologic appears to therapy for  Epilepsy dystonia,  Keep
class: sensitize tissues to adults with myoclonus, diphenhydramine
Dopaminergic action of symptomatic Precaution dizziness, anxiety. injection readily
blocker acetycholine; GERD who  Previously detected available in case
relaxes pyloric fail to respond breast cancer CV: Transient extrapyramidal
Therapeutic sphincter, which, to  Lactation hypertension reactions occur (50
Class: Antiemetic when combined conventional  Pregnancy mg IM)
GI stimulant with effects on therapy  Fluid overload GI: Nausea,  Have phentolamine
motility,  Prevention of  Renal impairment diarrhea readily available in
accelerates gastric nausea and case of hypertensive
emptying and vomiting Drug interaction crisis.
intestinal transit; Drug-Drug
little effect on  Decreased absorption During
gallbladder or of digoxin from the  Monitor BP
colon motility; stomach carefully during IV
increases lower administration
 Increased toxic and
esophageal  Monitor for
immunosuppressive
sphincter pressure; extrapyramidal
effects of cyclosporine
has sedative reactions, and
 Increased
properties; consult physician if
neuromascular
induces release of they occur
blocking effect of
prolactin.  Monitor diabetic
succinylcholine
patients
 Give direct IV doses
slowly over 1-2
minutes
 For Iv infusion, give
over at east 15
minutes.

After
 Dispose of used
 materials properly
 Educate patient
about side effects
 instruct to report
involuntary
movement of the
face, eyes, or limbs,
severe depression,
severe diarrhea
 Instruct not to use
alcohol, sleep
remedies or
sedatives; serious
sedation could
occur.
 Do proper
documentation