ABBAS ADEL

disease morphology transmis Infective feces blood CSF immunology others

sion agent
PROTOZOA
Entamoeba Amoebiasis *cyst -spherical,4 Digestive cyst Bloody and Anemia - AB's
Histylitica Prim - nuc, glycogen or rarely mucus. Leukocytosis Copro -AG's
amoebic chromidial bar sexua l Acute=T Neutrophilia
dysentery *trophozoite - Chronic=C ESR
scond- psudopodia,1 nuc,
ALA RBC's
Naegleria PAE * trophozoite - Intra- tropho - - Slug -like AB's - not
Fowlery Rocket shape,1 nasal zoite movment, always usuful
nuc,Ant pseudopodia Leukocytosis due to rapid
*flag. IM stage and PMN evolution
*cyst - trophozoites
Round and only in
culture,1 nuc
Acanthamoeba Imm.comp - *trophozoite - Ubiquitar both - - Cysts , -
keratitis Achanthopodia=proj existing Rarely
Chronic ections, 1 nuc+big lesions , tropho.
granu. Skin cariosome water
lesion *cyst -
Imm.supp- 1 nuc,double wall:
Chronic Ext -polygonal
granu. Int - wrinkled+pores
encephaliti
s
 ABBAS ADEL
FLAGELLATES
Giardia giardiasis *trophozoites - Fecal- cyst Chronic -C - - Serum AB's Duodenal
Duodenalis Flat,pear-like,4 pairs oral Acute - T Copro -AG's fluid exam. -
of flagella. Trophozoites
Venral – concave Non bloody
Dorsal-convex diarrhoea Intolerance
Ant - 2 nuc to lactose
*cyst -
4 nuc,axostile,double
coat
Trichomonas Trichomoniasis *trophozoite - Sexual tropho - No serology! - - Vaginal
Vaginalis 4 ant flagella+ 1 vertical zoite discharge -
recurrent,axostyl,cos tropho.
ta
*no cyst!
Leishmania Leishmaniasis *amastigote - Vector= Proma - Anemia - Specific AB's Leishmanoma.
spp Donovani IC form,nuc(large) sand fly stigote Thrombocytop Complication
&infantum enia
Visceral and Blood -PKDL
trasfusion, Donovani Leucopenia Amastigotes
kinetoplast(small)
Sexual, - MAN
Cutanous Tropica& In humans IgM in the
Vertical,
Major *promastigote - spleen,BM
digestive
Muco -cuta Elongated, ant and liver.
Brasil&mexico
flagella, 1 nuc and P romastigote
kinetoplast in culture
In the vector
 ABBAS ADEL
Trypanosoma African *trypomastigote - Tete fly Metacyc - Thin&thick Trypomastigote AB's * Trypanosomal
lic (long), chancre
brucei sleeping Elongated (glosina) blood film - AG's
trypoma At the
Gamb.&rhode sickness Kinetoplast-post Trypomastigote IgM
stigote beginning
s. Flagella- ant (short&long) proteins
High IgM *AG
Long and short
variation
*epimastigote - * winterbottom
Infective as
sign
Metacyclic
trypanosome
Trypanosoma chagas DH Triatoma metatr - Trypomastigote - ELISA *chagoma
cruzi *trypomastigote - ypoma IFAT Romana's
blood stigote sign
*amastigote - IC vertical *Amastigote
IH blood in muscles
* epimastigote trans *low
*metatrypomastigot parasitemia-
e xenoDG
#similar to brucei
only with a larger
kinetoplat
 ABBAS ADEL
COCCIDIA
Criptosporodium Cryptospo - *trophozoite - Digestive Mature Non bloody - - coproAG's *parvum -all
parvum Travllers cyst
rodiasis Located on the brush diarr. using GIT
border of the int. diarr. Cyst - monoclonal Muris-only
mucosa,extracytop sporozoites AB's initial part of
in a vacule on smear int.
*cyst -
Contain 4
sporozoites and a
tyzzer body.
#mature -
Thick coat with 5
layers
#immature -
Thin layer . Allows
the spread.
Isospora Belli isosporidiasis *trophozoite Digestive oocyst Oocysts - - - *enterotest -
*oocyst - Travllers Immsupp- duod liquid
Oval diarr. bloody
#mature - diarr.
2 sporocysts each
with 4 sporozoites
#immature -
2 undeveloped
sporocysts
 ABBAS ADEL
UNCERTAIN TOXONOMY
Pneumocystis PCP - *trophozoite - Imm.su tropho - *adults - - - *forms:
carinii pneumonia Thin coat, cenral pp. zoites Leucopenia Epidemic -
nuc, phylopodia Oral, Elevaten CO2 children
*pre -cyst Person and LDH Sporadic -
*cyst - to *children- Imm.supp
Contain 8 person Leukocytosis adults
sporozoites hypercalcemia *Sputum and
lung biopsy:
Cysts and
trophozoites
TISSUE COCCIDIA
Toxoplasma toxoplasmosis *trophozoite - CATS& oocyst - High present AB's *during preg.
Gondii Round end with the their eosinophiles AG's Screening-
nuc, and pointed end feces, *blood, PCR IgG avidity
with a complex for IC Digestive amniotic test
penetration. Tachy Blood fluid,tissue *clinical-
or brady. trans, sections,CSF- mononucleo
*tissue cyst - Organ parasites are sis like synd.
Spherical, modified tras, present
host cell=macroph. vertical
Contain bradyzoites
in a latent stage.
Brain or mm
*oocyst -
Oval,2 sporocysts
each with 4
sporozoites.