JOCEL OCLARIT BS PHARMACY

MIDTERM LABORATORY ACTIVITY 6

PHYSICAL PHARMACY
October 1, 2021

1. What factors favors the dissolving of solids in liquids?

 The rate of dissolving depends on the surface area (solute in solid state),
temperature and amount of stirring.

2. What factors favors the dissolving of gasses in liquids?

 An increase in pressure and an increase in temperature in this reaction results in
greater solubility.
An increase in pressure results in more gas particles entering the liquid in order to
decrease the partial pressure. Therefore, the solubility would increase.

3. In terms of molecular motions, explain the differences between the dissolving of solids in
liquid and the dissolving of gasses in liquids.

 A solid dissolves in a liquid when it mixes completely with the liquid. The solid
has broken down into pieces so small that its particles spread all throughout the
new mixture. Things which dissolve are called solutes and the liquid in which
they dissolve is called a solvent to form a solution.
 Gas molecules collide with the water surface. Some of them penetrate the
interface and diffuse into the water. Once away from the interface, they tend to
stay dissolved until they find their way back. The other mechanism is the
diffusion of dissolved gas molecules to the gas-liquid interface.

4. Which solid, potassium nitrate or sodium chloride is more soluble in water at the
temperature given?
*10 degrees celsius - NaCl Sodium chloride
*90 degrees celsius - KNO3 Potassium nitrate

5. What effect would an increase in pressure have on the solubility of solids in liquids?
 The effects of pressure changes on the solubility of solids and liquids are
negligible.
6. What effect would an increase in pressure have on the solubility of gasses in liquids?
 The higher the pressure above a liquid, the more gas that can be dissolved in that
liquid, to a limit of course. The solubility of gases depends on the pressure: an
 increase in pressure increases solubility, whereas a decrease in pressure decreases
solubility.

REFERENCES:

 https://chem.libretexts.org/Bookshelves/
Physical_and_Theoretical_Chemistry_Textbook_Maps/
Supplemental_Modules_(Physical_and_Theoretical_Chemistry)/Equilibria/Solubilty/
Solubility_and_Factors_Affecting_Solubility
 https://www.le.ac.uk/se/centres/sci/selfstudy/particle05.html
 https://www.thirteen.org/edonline/studentstake/water/schoolwater/dissolvedsolids/
dissolvedsolids.htm
 https://chem.libretexts.org/Bookshelves/
Physical_and_Theoretical_Chemistry_Textbook_Maps/
Supplemental_Modules_(Physical_and_Theoretical_Chemistry)/Equilibria/Solubilty/
Solubility_and_Factors_Affecting_Solubility