Drug Study

Magnesium Sulfate

Source: Nursing Drug Handbook 2020 (Wolter Kluwer) V1 & V2

Name of the Drug Classification Mechanism of Indication Contraindication Adverse Nursing Responsibilities
Action Reactions

Generic Name: General Magnesium sulfate Prevention and Contraindicated in CNS: Before:
● Magnesium Classification: depresses the CNS treatment of patients Ataxia,
Sulfate Anticonvulsant and controls seizure in hypersensitive to Confusion, 1. Consider the 10
convulsions by severe these drugs and Somnolence, Rights of Drug
blocking release of pre-eclampsia parenteral Tremor, Administrations
acetylcholine at the or eclampsia. administration of Drowsiness 2. Monitor pulse,blood
myoneural junction the drug is pressure,respiration
contraindicated CV: s and ECG
inpatients with Arrhythmias frequently
heart block Hypotension throughout
myocardial Flushing and administration of
damage. Sweating parenteral
Bradycardia magnesium sulfate
Circulatory 3. Monitor neurologic
status before the
administration
GI: 4. Respirations should
Vomiting be at least 16/min
before
administering.
Trade Name:

● Concept Ob Functional During

● Suprep Bowel Classification 1. Check Magnesium
Prep Kit ● Anticon Levels repeated
● Tandem Plus vulsant doses.Disappearanc
● Tis-U-sol e of knee. Jerk and
● Martham patellar reflexes are
signs of impending
magnesium toxicity.
2. Monitor urine intake
and output.
3. Do not give oral
MgSO with
abdominal pain,
nausea and vomiting
4. Give IM route by
deep IM injection
5. Monitor serum
magnesium levels.

Patient’s
Indication:

Patient’s Dose After

1. Observe neonates
for signs of
magnesium toxicity
2. Arrange to
discontinue
administration as
soon as levels are
 within normal limits
and desired clinical
response is
obtained.
3. Arrange for dietary
measures, exercise
and environmental
control to return to
normal bowel
activity.
4. Report sweating,
flushing, muscle
tremors or twitching,
inability to move
extremities.
5. Maintain urine
output at a level of
100 mL every 4 hr
during parenteral
administration.

Maximum Dose:
● 1-2 g qH by IV
infusion

Minimum Dose:
● 4-6 g qH by IV
infusion