David, Jovert Andrei

BSN3B5
DRUG STUDY - OMEPRAZOLE

GENERIC DOSAGE, ROUTE CLASSIFICATION MECHANISM INDICATION/ CONTRAIN ADVERSE NURSING

NAME ANDFREQUENCY OF ACTION PURPOSE -DICATION REACTION CONSIDERATIONS

Omeprazole IV: GERD Adult: Therapeutic: Bind to an enzyme GERD/maintenance Concomitant use CNS: dizziness, Advise patient to avoid
40 mg once daily antiulcer agents on gastric parietal of healing in with nelfinavir. drowsiness, fatigue, alcohol and foods that
Brand given via infusion cells in the erosive headache, weakness. may cause an increase in
name: over 20-30 minutes Pharmacologic: presence of acidic esophagitis.  Hypersensitivity GI irritation.
Prilosec until oral Proton-pump gastric pH, to omeprazole CV: chest pain
administration is inhibitors preventing the final Duodenal ulcers Instruct patient to report
possible. transport of (wtih or without Lactating mother GI: abdominal pain, bothersome or prolonged
  hydrogen ions into anti-infectives for acid regurgitation, side effects, including
Oral: GERD the gastric lumen. Helicobacter constipation, skin problems (itching,
Adult: 20 mg once pylori) diarrhea, flatulence, rash) or GI effects
daily for 4-8 weeks. Therapeutic nausea, vomiting. (nausea, diarrhea,
For severe case: 40 effects: Short-term vomiting, constipation,
mg once daily for 8 Diminished treatment of active Fluid and heartburn, flatulence,
weeks. Maintenance: accumulation of benign gastric Electrolyte: abdominal pain).
10 mg once daily, acid in the gastric ulcer. hypomagnesemia
may increase to 20- lumen with (esp. if treatment ≥ 3 Instruct patient to take
40 mg once daily if lessened Pathologic mons) medication as directed for
necessary. gastroesophageal hypersecretory the full course of therapy,
Child: ≥1 year reflux. Healing the conditions, Derm: itching, rash even if feeling better.
weighing 10-20 kg: duodenal ulcer. including
10 mg once daily, Zollinger-Ellison May cause occasional
MS: bone fracture
increased to 20 mg syndrome. drowsiness or dizziness,
once daily if advise patient to avoid
necessary. ≥2 years Misc: allergic
Reduction of risk of reaction driving or other activities
weighing >20 kg: 20 GI bleeding in requiring alertness.
mg once daily, critically ill
increased to 40 mg patients. Advise female patients to
once daily if notify the health care
necessary. Treatment professional if pregnancy
For OTC:
duration: 4-8 weeks. is planned or suspected or
heartburn occuring
≥  twice/week if breastfeeding.
David, Jovert Andrei
BSN3B5