RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.

SCIENCE LABORATORY SCHOOL

Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET LAS No. 38

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Activity Title: Carboxylic Acid

Learning Targets: To name carboxylic acid.
References: McMurry, J. Organic Chemistry Eight Edition, 2012, pp.:781

CARBOXYLIC ACID

 Carboxylic acids contain the carboxyl functional group, often written COOH [ ]. These
weak acids are widely distributed in nature and are common in consumer products. They are also
important in the manufacture of polymers used to make fibers, films, and paints.
 The common names of many carboxylic acids are based on their historical origins. Formic acid, for
example, was first prepared by extraction from ants; its name is derived from the Latin word
formica, “ant.”
Carboxylic acid derivatives—compounds in
which the -OH group of a carboxylic acid
has been replaced by another substituent
—are among the most widely occurring of
all molecules and are involved in almost all
biological pathways. Acid halides, acid
anhydrides, esters, and amides are the
most common such derivatives in the
laboratory; thioesters and acyl phosphates
are common in biological molecules.
Naming Carboxylic Acids
Simple carboxylic acids derived from open-chain alkanes are systematically named by replacing
the terminal -e of the corresponding alkane name with -oic acid. The -COOH carbon atom is numbered
C1.

Compounds that have a -COOH group bonded to a ring are named using the suffix - carboxylic
acid. The COOH carbon is attached to C1 in this system and is not itself numbered. As a substituent, the
COOH group is called a carboxyl group.

LAS No. 39

Do the exercise!Name the following substances.

1. 2.
___________________ ___________________________
Activity Title: Esters

RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020

 RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.
SCIENCE LABORATORY SCHOOL
Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Learning Targets: To determine the properties and uses of esters.

References: McMurry, J. Organic Chemistry Eight Edition, 2012, pp.836

Esters
¤ Esters are among the most widespread of all naturally occurring compounds. Many simple esters are
pleasant-smelling liquids that are responsible for the fragrant odors of fruits and
flowers.
¤ For example, methyl butanoate is found in pineapple oil, and isopentyl acetate is a
constituent of banana oil. The ester linkage is also present in animal fats and in many
biologically important molecules.
¤ The chemical industry uses esters for a variety of purposes. Ethyl acetate, for instance, is a
commonly used solvent, and dialkyl phthalates are used as plasticizers to keep polymers from
becoming brittle. You may be aware that there is current concern about possible toxicity of
phthalates at high concentrations, although a recent assessment by the U.S. Food and Drug
Administration found the risk to be minimal for most people, with the possible exception of male
infants.

Some example of Esters

Do the exercise! Write true if the statement is correct and false if incorrect.
______ 1. Esters are among the carboxylic derivatives.

______ 2. The name ending of esters is –acid.

______ 3. Esters is present in animal fats.

______ 4. Simple esters are pleasant smelling responsible for odors of plants.

______ 5. Acetic acid is an example of esters.

RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020

 RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.
SCIENCE LABORATORY SCHOOL
Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET LAS No. 40

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Activity Title: Amines

Learning Targets: To name amines.
References: McMurry, J. Organic Chemistry Eight Edition, 2012, pp.944

Amines are organic derivatives of ammonia in the same way that alcohols and ethers are organic derivatives
of water. Like ammonia, amines contain a nitrogen atom with a lone pair of electrons, making amines both basic and
nucleophilic. In fact, that most of the chemistry of amines depends on the presence of this lone pair of electrons.
Amines occur widely in all living organisms. Trimethylamine, for instance, occurs in animal tissues and is
partially responsible for the distinctive odor of fish; nicotine is found in tobacco; and cocaine is a stimulant found
in the leaves of the South American coca bush.
Naming Amines
¤ Amines are named in the IUPAC system in several ways. For simple amines, the suffix -
amine is added to the name of the alkyl substituent.
Cyclohexylamine

¤ Alternatively, the suffix -amine can be used in place of the final -e in the name of the parent compound.

¤ Substituted amines are named as N-substituted amines. The largest alkyl group is chosen as the parent
name, and the other alkyl groups are considered N-substituents on the parent (N because they’re attached
to nitrogen).

¤ Amines with more than one functional group are named by considering the -NH2 as an amino substituent on
the parent molecule.

Heterocyclic amines—compounds in which the nitrogen atom occurs as

part of a ring—are also common, and each different heterocyclic ring
system has its own parent name. The heterocyclic nitrogen atom is
always numbered as position 1.

Do the exercise!Name the following substances.

1. CH3NHCH2CH3 2. 3.
___________ _____________ _______________
RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020
 RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.
SCIENCE LABORATORY SCHOOL
Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET LAS No. 41

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Activity Title: Amides

Learning Targets: To name amides
References: McMurry, J. Organic Chemistry Eight Edition, 2012, pp.843

Amines are compounds in which one or more of the hydrogens

of ammonia (NH3) are replaced by an alkyl group:

An amine with at least one H bonded to N can undergo a condensation reaction with a carboxylic acid to
form an amide, which contains the carbonyl group (C=O) attached to N.

We may consider the amide functional group to be derived from a carboxylic acid with an NRR’ group
replacing the OH of the acid, as in these examples:

Amides, like esters, are abundant in all living organisms. Proteins, nucleic acids, and many pharmaceutical
agents have amide functional groups. The reason for this abundance of amides is that they are stable to the
aqueous conditions found in living organisms. Amides are the least reactive of the common acid derivatives.

Naming Amides: RCONH2

Amides with an unsubstituted -NH2 group are named by replacing the – oic acid or -ic acid ending with -
amide, or by replacing the -carboxylic acid ending with -carboxamide.

If the nitrogen atom is substituted, the amide is named by first identifying the substituent groups and then the
parent amide. The substituents are preceded by the letter N to identify them as being directly attached to
nitrogen.

Do the exercise!Name the following substances.

1. 2. 3.
__________________ ___________________ _____________________

RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020

 RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.
SCIENCE LABORATORY SCHOOL
Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET LAS No. 42

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Activity Title: Carboxylic acids, Amines and Amides

Learning Targets: To name carboxylic acid, amines, and amides
References: McMurry, J. Organic Chemistry Eight Edition, 2012,

Activity. Give the IUAC Name following substances. (4 points each)

1. _________________________________

2. _________________________________

3. ______________________________________________

4. ______________________________________________

5. ______________________________________________

RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020

 RC- AL KHWARIZMI INTERNATIONAL COLLEGE FOUNDATION, INC.
SCIENCE LABORATORY SCHOOL
Barrio Marawi, National Highway, Marawi City
School ID: 478017
S.Y. 2020-2021

LEARNING ACTIVITY SHEET LAS No. 43

Name: ___________________________________________________
Grade Level and Section: 10 -_________________ Score: __________________
Subject: SCIENCE 10.2 (Organic and Biochemistry) Date: __________________
Type of Activity:
Concept Notes Laboratory Report Formal Theme Others:
z
Skills/ Exercise/ Drills Drawing/ Art Informal Theme

Activity Title: Carboxylic acids, Amines and Amides

Learning Targets: To draw the structural formula of carboxylic acid, amines, and amides
References: McMurry, J. Organic Chemistry Eight Edition, 2012

Activity. Draw the structural formula of the following compounds. (4 points each)
1) Methylpyrrolidine

2) 2,3-Dimethylhexanoic acid

3) Methylbutanoate

4) Hexanamide

5) N-methylbutanamide

RC AKICFI-SLS OBILP Revised Learning Activity Sheet 2020