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Name: Carter___________

Mark (out of 60):_________


SBI 3U: Genetic Continuity

Multiple Choice (13 marks): Identify the letter of the choice that best completes the statement or answers the
question.

_c__ 1. Meiosis is important because it:


a Replaces dead cells. d Allows for growth.
. .
b Allows for genetic continuity. e None of the above.
. .
c Allows for genetic variation.
.

_d__ 2. During meiosis, genetic variation in the gametes is achieved by


a replication and fertilization. d crossing over and random assortment.
. .
b crossing over and replication. e replication and random assortment.
. .
c crossing over and fertilization.
.

_a__ 3. The haploid chromosome number in humans is


a 23. d 92.
. .
b 46. e 69.
. .
c 48.
.

_c__ 4. Mendel's First Law (the Law of Segregation) states that


a the dominant form of a trait will appear in every generation.
.
b members of different pairs of genes behave independently during meiosis.
.
c genes are carried in pairs and separate during meiosis to be distributed into different sex
. cells.
d the probability of two or more independent events occurring together is the product of
. the individual probabilities.
e if genes are located on separate chromosomes, they are inherited independently of each
. other.

_a__ 5. In a dihybrid cross, the only combination of parents that can produce the phenotypic ratio 9:3:3:1 is:
a SsYy x SsYy d SSyy x ssYY
. .
b SSYY x ssyy e SsYy x SSYy
. .
c ssYY x ssyy
.

_a__ 6. A gene exists in two different forms (A and a). With respect to the allele present, which type of
gamete can a homozygous recessive individual produce?
a a d A and a
. .
b A e AA
. .
c Aa
.
_a__ 7. The gene makeup of an organism for a particular trait is its
a genotype. d recessiveness.
. .
b pedigree. e dominance.
. .
c phenotype.
.

_c__ 8. The physical appearance of an organism for a particular trait is its


a genotype. d recessiveness.
. .
b pedigree. e dominance.
. .
c phenotype.
.

_c__ 9. Incomplete dominance occurs when


a one allele prevents the expression of the other allele.
.
b the traits occur randomly when the alleles occur together.
.
c one allele’s trait is masked by the presence of another allele.
.
d a mixture of traits is expressed when the alleles occur together.
.
e the alleles appear only on the sex chromosomes.
.

_d__ 10. Colourblindness is a sex-linked characteristic because the gene is


a dominant. d carried on a sex chromosome.
. .
b recessive. e homozygous.
. .
c carried on an autosome.
.

_b__ 11. Which of the following is true of sex-linked traits?


a Both genders are affected equally.
.
b Males are affected more frequently than females.
.
c Males and females can be carriers.
.
d Males can inherit the trait from their mother or their father.
.

_c__ 12. Which of the following is true of autosomal traits?


a They are carried on the X chromosome.
.
b Males inherit only one copy.
.
c Both genders are affected equally.
.
d Males are affected more often than females.
.

_a__ 13. Which of the following is true of dominant traits?


a You only need one copy of the allele to express the trait.
.
b You can carry the trait without expressing it.
.
c You can pass the trait to your offspring without expressing it yourself.
.
d You can express the trait even if neither of your biological parents did.
.

Matching (15 marks)


Match each item with the correct statement below.
a trisomy- f. co-dominance -
.
b monosomy- g incomplete dominance -
. .
c non-disjunction- h homozygous-
. .
d allele- i. heterozygous-
.
e gene - j. locus-
.
_c__ 14. failure of chromosomes to separate during anaphase.
_e__ 15. a sequence of DNA that carries a particular trait.
_f__ 16. expression of two alleles at the same time.
_j__ 17. the position of a gene on a chromosome.
_d__ 18. a version of a gene on a chromosome.
_a__ 19. an extra copy of a chromosome in a cell.
_g__ 20. expression of two alleles resulting in an intermediate condition.
_h__ 21. identical alleles on a pair of chromosomes.
_b__ 22. a missing copy of a chromosome in a cell.
_i__ 23. differing alleles on a pair of chromosomes.

The black and yellow pigments in the coats of cats are controlled by a sex-linked pair of alleles,
located on the X-chromosome. The "tortoise shell"' or "calico" cat is the heterozygous condition.
Using B to represent the black allele, and Y for the yellow allele, match each item with the correct
statement below.
a XYXY d XBY
. .
b XYY e XBXY
. .
c XX B B

.
_e__ 24. a calico __d__ 25. a black male _c__ 26. a black female
_b__ 27. a yellow male __a__ 28. a yellow female
Short Answers (32 marks)
1) In dogs, wiry hair is due to a dominant factor, smooth hair is its recessive. Predict the phenotype(s) of the
offspring in a cross between a pure-bred wire-haired dog and a smooth- haired dog. (3 marks)

Assuming the parent dogs are WW (wiry) and ss (smooth), the only phenotype the offspring could
have would be Ws. Since wiry hair is the dominant trait, they would all be wiry-haired.

W W
s Ws Ws

s Ws Ws

2) Complete the table below for the different blood types: (4 marks)

Blood Possible Genotypes Surface Proteins (ex. What type of blood can a
Type Antigen A, Antigen B, person with this blood type
none…) receive ?
A AA, AO Antigen A A, O

B BB, BO Antigen B B, O

AB AB Antigens A and B A, B, AB, O

O OO None O

4) Adam has blood type AB. His father was type B and his mother was type A. Adam’s wife Mary has
blood type B. Mary’s mother was blood type O and her father was blood type B. What are the chances that
Adam and Mary’s first son, Cain, will have type A blood? (4 marks)

idk lol but we know abel’s blood type cuz its all over the ground

5) The human ABO blood types exhibit both dominance and co-dominance. Explain. (2 marks)
6) Tallness is dominant to dwarfness, while red flower colour is due to one gene and white due to another.
The heterozygous condition results in red and white flower colour. A dwarf red snapdragon is crossed with
a plant homozygous for tallness and white flowers. What are the genotypes and phenotypes of the F 1
individuals? (5 marks)

7) Joel and Amanda rushed their 1-year-old son David to the hospital after he fell and scraped his arm and
they could not stop the bleeding. David’s parents were sad to find out that he inherited the genetic disorder
Hemophilia. Although there were no known cased of Hemophilia in Joel’s family, 2 of Amanda’s brothers
had the same disorder. Show the pedigree (3 marks), determine each person’s genotype (3 marks) and
state the type of disorder that Hemophilia is (1 mark).

8a) Throughout the unit, we followed the case of Nancy and Jake. Since both of them found of they are
carriers of a faulty cystic fibrosis gene, what option do they have in testing their unborn baby? (3 marks)

amniocentesis

b) The current therapies available to treat CF only treat the symptoms of the disorder. However, if gene
therapy were to work, it could be considered a cure rather than a mere treatment of the symptoms. Explain
why this could be the case (4 marks)

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