Professional Documents
Culture Documents
• Hyperthermia Mechanism:
o ``
Recall:
E
2
SAR W / Kg
• Boundary conditions between different tissues is of major
significance.
• Example: Fat and muscle interface
915 MHz Fat Muscle
0.13 1.3
` 5.5 51
f 1 Ef
, 10
m 10 Em
• Extra fat heating
Hyperthermia
Depth of Penetration
Localization
Concentration of the fields in
the tumor without affecting
surrounding tissue.
T
c kT JE Qh
t
Current
J E
Heat heat loss
Electric field
Density Heat
T density
Joule Heatto blood
intensity
hb (T Tbl ) perfusion
Time
Change k Conduction
n Electrical
conductivity
Heat transfer coefficient Blood temperature
Potential Hyperthermia Techniques
Cell surface
receptor
Cell
Au coating
coating
Magnetic nanoparticle
Transcranial Magnetic Stimulation
Coil 2
C.
Induced E field