Cells are the building blocks/basic units of composed of DNA and protein all living things. Plasma Membrane ANATOMY OF THE CELL • Fragile, transparent barrier for cell Cells are not all the same Contents
• All cells share general structures Hydrophilic (Water- loving) Heads
• Polar heads of phospholipid Cells are organized into three main molecules Regions: • Attracted to water 1. Nucleus 2. Cytoplasm Hydrophobic (Water- hating) Tails 3. Plasma membrane • Nonpolar tails of phospholipid Nucleus (nucle = kernel) molecules • Located near the center of the cell • Avoid water
• Headquarter/control center of the cell Role of proteins
• Contains genetic material (DNA) Responsible for specialized
membrane functions: • Shape conforms to the shape of the cell • Enzymes • A round or oval body that is surrounded • Receptors for hormones or other chemical messengers by the nuclear envelope • Transport as channels or carriers Nucleus 3 regions: Role of sugars 1. Nuclear membrane/envelope Glycoproteins are branched sugars 2. Nucleolus attached to proteins that abut the 3. Chromatin extracellular space Glycocalyx is the fuzzy, sticky, Deoxyribonucleic Acid (DNA) sugar- rich area on the cell’s The blueprint that contains all the surface instructions needed for building the whole body. Plasma Membrane Nucleoli (little nuclei) Specializations • Refers to one or more small, dark- Microvilli staining, essentially round bodies • Finger-like projections that Nuclear Envelope/Nuclear Membrane increase surface area for absorption Example: intestine • Double membrane barrier of the Membrane Junctions Nucleus Tight Junctions Are the closely associated areas of two cells whose membranes join together forming a virtually • Usually they are rod-shaped, however impermeable barrier to fluid. they can be round. Desmosomes (Macula adherens) • In living things, they squirm, lengthen, A cell structure specialized for cell- to-cell adhesion and change shape almost continuously
Gap Junctions A. Outer membrane – smooth &
They directly connect the featureless cytoplasm of two cells, which B. Inner membrane – has shelf like allows various molecules, ions and protrusions called cristae (crests) electrical impulses to directly pass through a regulated gate between cells. Ribosomes Tiny, bilobed, dark-stained bodies made of Cytoplasm protein and one variety of RNA (ribosomal Cellular material outside the RNA) nucleus and inside the plasma membrane. Endoplasmic Reticulum
3 major elements: Membranous system of tubules that
1. Cytosol extends throughout the cytoplasm Fluid that suspends other Exist in 2 forms: elements The fluid in which the Rough ER organelles of the cytoplasm are suspended; • Studded with ribosomes Also called the ground substance of the cell. • Tubules of rough ER provide an area for storage and transport of the proteins made 2. Organelles on the ribosomes to other cell areas
Metabolic machinery of the Smooth ER
cell 3. Inclusions • It has no function in protein synthesis Non-functioning units • It is a site for steroid and lipid synthesis, Chemical substances that lipid metabolism, and drug detoxification may or may not be present; most are stored Golgi Apparatus nutrients or cell products Stacks of flattened sacs with bulbous ends Cytoplasmic Organelles and associated small vsicles Literally means “little organs.” Lyzosomes Mitochondria (mitos = thread) Various-sized membranous sacs containing powerful digestive enzymes. Singular: mitochondrion • Tiny threadlike or sausage-shaped organelles Peroxisomes Cilia Small lysozomes- like membranous sacs • moves materials accross cell surface containing oxidase (oxygen) enzymes that detoxify alcohol, hydrogen peroxide, and Flagellum other harmful chemicals • propels the cell Centrioles Events of Cell Division Paired cylindrical bodies lie at right angles Mitosis to each other close to the nucleus • The division of the copied DNA of the Cytoskeleton mother cell to 2 daughter cells • Provide cellular support by forming an Stages: internal scaffoldings 1. Prophase • Function also in intracellular transport 2. Metaphase • It has 3 different types: 3. Anaphase 1. Microfilament 4. Telophase 2. Intermediate filament 3. Microtubules Interphase
Microfilaments: • Not part of mitosis (no cell division
Ribbon or cordlike elements occurs)- inactive phase
Formed largely of actin (a Prophase contractile protein), thus are important in cell mobility, • First part of cell division particularlyin muscle cells • Chromatin condenses, forming bar-like Intermediate Filament: Chromosomes • Proteinaceous cytoskeletal elements that act as internal guy wires to resist Late Telophase mechanical (pulling) forces acting on cells • The nuclear envelope breaks up, Microtubules allowing the spindle to interact with the chromosomes • Slender tubules formed of proteins called tubulins Metaphase
Cellular Projections • Chromosomes cluster and become
aligned at the metaphase plate (the center Not found in all cells of the spindle midway between the centrioles) so that a straight line of is seen Use for movements Anaphase • The shortest phase of mitosis • It begins abruptly as the centromeres splits simultaneously Telophase • Like prophase in reverse • Identical chromosomes at opposite ends of the cell uncoil to become chromatin Cytokinesis • Division of the cytoplasm • Begins when mitosis is near completion