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Billions of years ago, life existed on Earth. About how it all began is still a mystery
but time slowly unveils these wonders allowing us to understand life better. In your past
lesson, you have learned about the very foundation of life- cells. Several studies have been
conducted and came up with unifying tenets about the basic unit of life which is collectively
known as the Cell Theory. You have also walked through the several organelles that make up
a cell and their general functions. Today, you will be learning more about cells.
The term cell was coined from cellulae, meaning “small rooms”. There are cases that
a room with several furniture is already enough for you to stay and live. Some houses are
made up of several rooms and a greater number of furniture. Just like the analogy where the
cell term was coined from, there are organisms existing with only one cell, others have
multiple cells, and some differ with the organelles they compose.
All living things can be divided into three basic domains: Bacteria, Archaea and
Eukarya. The primarily single-celled organisms found in the Bacteria and Archaea domains
are known as prokaryotes. These organisms are made up of prokaryotic cells — the smallest,
simplest and most ancient cells.
Organisms in the Eukarya domain are made of the more complex eukaryotic cells.
These organisms, called eukaryotes, can be unicellular or multicellular and include animals,
plants, fungi and protists.
All living things have cells that share fundamental structural parts which include:
DNA: It is a genetic coding that determines all the characteristics of living things.
Cell (or plasma) membrane: It is the outer layer that separates the cell from the
surrounding environment and acts as a selective barrier for incoming and outgoing
materials.
Cytoplasm: It is a jelly-like fluid within a cell that is composed primarily of water,
salts and proteins.
Ribosomes: These are organelles that make proteins.
Differences of prokaryotic and eukaryotic cell according to Pedersen (2019)
Animals have four tissues in general. This includes epithelial, connective, muscle and
nervous (Farabee, 2007).
1. Epithelial tissue covers body surfaces and lines body cavities. Functions include
lining, protecting, and forming glands. Three types of epithelium occur:
Squamous epithelium is flattened cells that allows the movement of materials
and nutrients through the cells, that is, passive diffusion.
Cuboidal epithelium is cube-shaped cells located in the pancreas and kidney
tubules, they help in absorption of nutrients as well as secretion of hormones,
sweat, wax, digestive enzymes and even milk.
Columnar epithelium consists of elongated cells. The function of the columnar
epithelial cells is secretion and absorption of nutrients. The columnar epithelial
cells in the intestine contain microvilli that helps in increasing the surface are
for absorption.
2. Connective tissue serves many purposes in the body. Functions include binding,
supporting, protecting, forming blood, storing fats and filling space.
Bone is the strongest connective tissue with little ground substance, hard matrix
of calcium and phosphorous and specialized bone cells called osteocytes. It
provides protection to internal organs and supports the body.
Loose connective tissue is found between many organs where it acts both to
absorb shock and bind tissues together. It allows water, salts, and various
nutrients to diffuse through to adjacent or imbedded cells and tissues. Loose
connective tissue includes adipose tissue, areolar tissue and reticular tissue.
o Adipose tissue consists mostly of fat storage cells called adipocytes.
o Areolar tissue shows little specialization. It contains all the cell types
and fibers and is distributed in a random, web-like fashion. It fills the
spaces between muscle fibers, surrounds blood and lymph vessels, and
supports organs in the abdominal cavity.
o Reticular tissue is a mesh-like, supportive framework for soft organs
such as lymphatic tissue, the spleen, and the liver. Reticular cells
produce the reticular fibers that form the network onto which other cells
attach.
Blood is a connective tissue of cells separated by a liquid (plasma) matrix. Two
types of cells occur. Red blood cells (erythrocytes) carry oxygen. White blood
cells (leukocytes) function in the immune system. Plasma transports dissolved
glucose, wastes, carbon dioxide and hormones, as well as regulating the water
balance for the blood cells. Platelets are cell fragments that function in blood
clotting.
4. Nervous tissue functions in the integration of stimulus and control of response to that
stimulus. Nerve cells are called neurons. Each neuron has a cell body, an axon, and
many dendrites. Nervous tissue is composed of two main cell types: neurons and glial
cells. Neurons transmit nerve messages. Glial cells are in direct contact with neurons and
often surround them. They maintain homeostasis, form myelin, and provide support and
protection for neurons.
LEARNING COMPETENCY
DIRECTIONS/INSTRUCTIONS
Perform the following activities. If you are at home you can have the activity together
with your family. Take note of each step. If you have questions, you can contact your teacher
for clarifications and assistance. Enjoy learning!
EXERCISES
Above
Below Average Average Excellent
Diagram Average
(1-3 points) (4-6 points) (9-10 points)
(7-8 points)
3D model
3D model Highly
appearance
Creativity and appearance Creative 3D creative,
shows least
appearance meets lesson model exceptional
effort
requirements. 3D model
required.
Score
ACTIVITY 4: Into the Different Cell Types
1. Based from your previous readings, complete the concept map of a plant tissue below.
2. Based from your previous readings, complete the concept map of an animal tissue below.
ACTIVITY 5: Life Connections
Read the given text below about classifying cells present in urine to test and detect
possible diseases. Answer the questions below. Write your answer on the space provided for
each item.
A urinalysis is simply an analysis of the urine. It is a very common test that can be
performed in many health care settings, including doctors' offices, urgent care facilities,
laboratories, hospitals, and even at home.
A urinalysis test is performed by collecting a urine sample from the patient in a
specimen cup. Usually only small amounts (30-60 mL) may be required for urinalysis testing.
The sample can be either analyzed in the medical clinic or sent to a laboratory to perform the
tests.
Urinalysis is commonly used to diagnose a urinary tract or kidney infection, to
evaluate causes of kidney failure, to screen for progression of some chronic
conditions such as diabetes mellitus and high blood pressure.
The microscopic urinalysis is the study of the urine sample under a microscope. It
requires only a relatively inexpensive light microscope. Cells and cellular debris, bacteria,
and crystals in the urine (crystalluria) can be detected by microscopic examination to provide
confirmation of the dipstick.
Epithelial cells (flat cells), red and white blood cells may be seen in the urine.
Sometimes cells, cellular debris, and casts are seen in the microscopic exam.
Epithelial cells (cells in the lining of the bladder or urethra) may suggest inflammation within
the bladder, but they also may originate from the skin and could be contamination.
Casts and cellular debris originate from higher up in the urinary tract, such as in the
kidneys. These are material shed from kidney cell lining due to injury or inflammation and
travel down through the urinary tubes. These usually suggest an injury to the kidney from an
inflammation or lack of blood flow to the kidneys. Rarely, tumor cells can be in the urine
suggesting a urinary tract cancer.
A high count of red blood cells in the urine can indicate infection, trauma, tumors, or
kidney stones. If red blood cells seen under microscopy look distorted, they suggest kidney as
the possible source and may arise due to kidney inflammation (glomerulonephritis). Small
amounts of red blood cells in the urine are sometimes seen among young healthy people and
usually are not indicative of any disease.
The number of leukocytes is often a measure of disease. They make up approximately
1% of blood in a healthy adult. A change in the amount of leukocytes can often be used to
diagnose disease. Urine is a generally thought of as a sterile body fluid, therefore, evidence of
white blood cells or bacteria in the urine is considered abnormal and may suggest a urinary
tract infection such as, bladder infection (cystitis), infection of kidney (pyelonephritis).
**Adapted from: Fareed, K. (n.d.) Urinalysis (Urine Test). MedicineNet. Retrieved from:
https://www.medicinenet.com/urinalysis/article.htm
Guide Questions:
1. In your own opinion, how important is cell type identification in the field of medicine?
2. What are the cell types that can be found in urine and what are the diseases they indicate?
3. What do you think is the basis of doctors in claiming that the presence of white blood cells
in urine may suggest urinary tract infection? Relate your explanation with the function of
white blood cells.
REFLECTION
1. I learned that
2. I enjoyed most on
Bailey, R. (2018). Learn about plant cell types and organelles. ThoughtCo. Retrieved
from: https://www.thoughtco.com/what-is-a-plant-cell-373384
Farabee, M. (2006). Animal cells and tissues. Online Biology Book. Estrella Mountain
Community College. Retrieved from:
https://www2.estrellamountain.edu/faculty/farabee/biobk/BioBookAnimalTS.ht
ml
Farabee, M. (2007). Plants and their structure. Online Biology Book. Estrella Mountain
Community College. Retrieved from:
https://www2.estrellamountain.edu/faculty/farabee/biobk/BioBookPLANTANAT
.html#Links
Pedersen, T. (2019). Prokaryotic vs. Eukaryotic Cells: What’s the Difference? Live Science.
Retrieved from: https://www.livescience.com/65922-prokaryotic-vs-eukaryotic-
cells.html