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IN PRACTICE

women's health

A Primer on the New Guideline for the


Prevention, Detection, Evaluation, and
Management of Hypertension
Carina Katigbak & Holly B. Fontenot

ABSTRACT: Hypertension is a leading risk factor for the development of cardiovascular disease. In 2017, the American College of
Cardiology and the American Heart Association published a new guideline for the prevention, detection, evaluation, and management
of hypertension. The guideline adjusts the clinical parameters for diagnosis and management of hypertension. In this article we
summarize the updates and provide some background on these changes as they relate to nursing practice implications, with specific
implications for women’s health.
doi: 10.1016/j.nwh.2018.06.003 Accepted May 2018
KEYWORDS: blood pressure, cardiovascular disease, guideline, hypertension, pre-hypertension, Stage 1 hypertension, Stage 2
hypertension, stroke
Photo ª geckophotos / iStockphoto.com

U
ncontrolled hypertension is a critical modifiable risk condition under control (Yoon, Fryar, & Carroll, 2015),
factor in the development and progression of a increasing their risk for cardiovascular disease and stroke. For
number of conditions, including cerebrovascular women, cardiovascular disease is the leading cause of death,
disease and cardiovascular disease. Approximately 75 million accounting for one out of every three female deaths (Garcia,
Americans, or one third of the U.S. adult population, have high Mulvagh, Merz, Buring, & Manson, 2016). Epidemiologic
blood pressure (Centers for Disease Control and Prevention, evidence shows that although hypertension prevalence is
2016), and only slightly more than half (54%) of them have the lower among adult women compared with men from ages 18

346 ª 2018 AWHONN; doi: 10.1016/j.nwh.2018.06.003 nwhjournal.org


Katigbak & Fontenot

CLINICAL IMPLICATIONS
n Uncontrolled hypertension is a critical modifiable risk factor in the
development and progression of cerebrovascular disease and
cardiovascular disease.
n The American College of Cardiology and the American Heart
Association have released a new guideline for the prevention,
detection, evaluation, and management of hypertension.
n The new guideline emphasizes early detection of high blood
pressure and adoption of nonpharmacologic lifestyle
interventions such as losing weight, increasing physical activity,
moderating alcohol consumption, and quitting smoking.
n Nurses play a critical role in disease prevention by assessing for
risk and providing education and counseling.
n Nurses are ideally positioned to screen for high blood pressure
and to initiate therapeutic options at any point in a woman’s life
span.

to 59 years, this trend reverses itself for older adults ($60


years old) such that high blood pressure is more prevalent
among women than men in this age group (Yoon, Fryar, & Approximately 75 million Americans
Carroll, 2015). have high blood pressure, and only
In 2017, the American College of Cardiology (ACC) and the
American Heart Association (AHA) published new a guideline slightly more than half of them have
for the prevention, detection, evaluation, and treatment of the condition under control
hypertension—the first comprehensive update to the blood
pressure guideline since the 2003 Joint National Committee
on the Prevention, Detection, Evaluation, and Treatment of (meta-analyses were performed where possible) to deter-
High Blood Pressure (JNC7). In this article we review the mine the following: (a) whether self-directed blood pressure
updated ACC/AHA Hypertension Guideline, summarizing key monitoring/ambulatory blood pressure monitoring is more
changes and their implications for nursing practice, and effective than office-based blood pressure monitoring by a
women’s health. health care provider in achieving better blood pressure
control and preventing adverse outcomes for those with
hypertension risks, (b) the optimal blood pressure target for
History and Overview of Hypertension people being treated with antihypertensive medication, (c)
Treatment Guidelines whether various antihypertensive medications vary in terms
In response to the growing burden of cardiovascular dis- of their comparative harms and benefits, and (d) whether
ease and its known links to hypertension, the National initiating antihypertensive medication treatment with one
Heart, Lung, and Blood Institute began producing a series drug is more beneficial than starting with two drugs.
of hypertension guidelines in 1977. These guidelines Although it is beyond the scope of this clinical summary to
evolved over time to become, in 2003, the JNC7. Its most discuss the methodologies used in conducting the review of
recent iteration, JNC8, was published in 2014 and the evidence, a thorough description was given by P. K.
emphasized greater control of systolic blood pressure and Whelton et al. (2018).
diastolic blood pressure, along with age- and comorbidity- The new guideline recommends an aggressive approach to
specific treatment cutoffs (James et al., 2014). In 2014, blood pressure management and advocates for a risk-based
the ACC and the AHA collaborated with nine other profes- approach to prevention and treatment. It emphasizes the
sional associations to develop the new hypertension clinical importance of accurate blood pressure measurement, lowers
Photo ª LordHenriVoton / iStockphoto.com

practice guideline (P. K. Whelton et al., 2018). A team of the blood pressure threshold for defining hypertension, and
multidisciplinary experts oversaw four systematic reviews recategorizes blood pressure into normal, elevated, Stage 1
hypertension, and Stage 2 hypertension. Shared decision
making between providers and patients and team-based care
Carina Katigbak, PhD, RN, ANP-BC, is an assistant professor, William F. are further emphasized in terms of establishing an evidence-
Connell School of Nursing at Boston College in Chestnut Hill, MA. Holly B.
based plan of care that incorporates self-management, timely
Fontenot, PhD, RN, WHNP-BC, is an associate professor, William F. Connell
School of Nursing at Boston College in Chestnut Hill, MA. The authors report
follow-up, home-based blood pressure monitoring, and greater
no conflicts of interest or relevant financial relationships. Address attention to lifestyle interventions to prevent disease
correspondence to: katigbac@bc.edu. progression.

August 2018 Nursing for Women’s Health 347


New Hypertension Guideline

TABLE 1 OLD AND NEW BLOOD PRESSURE CATEGORIES


Blood Pressure JNC7 ACC/AHA 2017 Guideline
<120/80 mm Hg Normal blood pressure Normal blood pressure
120–129/<80 mm Hg Prehypertension Elevated blood pressure
130–139/80–89 mm Hg Prehypertension Stage 1 hypertension
‡140/‡90 mm Hg Stage 1 hypertension Stage 2 hypertension
‡160/‡100 Stage 2 hypertension Stage 2 hypertension

Blood Pressure Classification The new guideline provides seven tips for health care pro-
The most impactful change in the new guideline is the new viders to accurately measure blood pressure. Improper patient
definition and reclassification of stages of high blood pres- preparation (e.g., not emptying bladder, caffeine consumption
sure. A normal blood pressure, as defined by both the JNC7 before measurement), improper patient positioning, and
and the new guideline, remains less than 120/80 mm Hg. inappropriate cuff size/cuff placement all can lead to inac-
Prehypertension is reclassified into two new categories: curate blood pressure measurements with inaccuracies
elevated blood pressure (120–129/<80 mm Hg) and Stage 1 ranging from 5 to 50 mm Hg (Kallioinen, Hill, Horswill, Ward, &
hypertension (130–139 mm Hg systolic pressure or 80– Watson, 2017; Ringrose, Wong, Yousefi, & Padwal, 2017;
89 mm Hg diastolic pressure), effectively lowering the Ozone et al., 2016).
threshold by which clinicians diagnose hypertension to The new guideline recommends out-of-office/home-based
130 mm Hg or greater systolic blood pressure and 80 mm Hg blood pressure measurement and self-monitoring to confirm
or greater diastolic blood pressure. Stage 2 hypertension is hypertension diagnosis when an elevated blood pressure has
classified as 140/90 mm Hg or greater (see Table 1). been detected in health care settings and to guide titration of
The rationale for these new definitions is based on evi- blood pressure–lowering medication; or alternately, to screen
dence from several meta-analyses in which researchers re- for white coat hypertension or masked hypertension before
ported a gradient in cardiovascular disease risk that rises as providing a diagnosis of hypertension. Providers must educate
blood pressure increases from normal to elevated to hyper- and work with patients on proper at-home blood pressure
tension (Guo, Zhang, Guo, et al., 2013; Guo, Zhang, Zheng, measurement techniques and documentation practices.
et al., 2013; Huang et al., 2014; Shen, Ma, Xiang, & Wang, Numerous tools and resources are available for providers and
2013), in addition to observational data (Lewington et al., patients to use toward achieving blood pressure goals, such
2002) and randomized trials of lifestyle interventions to lower as “Target:BP” (2016), a recent collaboration between the
blood pressure (S. P. Whelton, Chin, Xin, & He, 2002). As AHA and American Medical Association that provides free
systolic blood pressure exceeds 120 mm Hg, cardiovascular online resources for clinicians and patient tools such as self-
disease risk increases, and this risk doubles with systolic care tips and checklists for at-home blood pressure moni-
blood pressure of 130 mm Hg or greater. toring to promote engaged decision making (see Box 1).
This change to the definition of hypertension substantially
increases the proportion of U.S. adults with hypertension from Risk-Based Treatment Approach
one third to one half of the U.S. adult population (Muntner The new guideline includes a risk-based approach to treat-
et al., 2018). However, this growth in newly diagnosed hy- ment. The authors recommend that health care providers
pertension cases translates to a small increase (1.9%) in the consider an individual’s risk for experiencing events related to
number of U.S. adults for whom antihypertensive medications atherosclerotic cardiovascular disease—defined as family
would be prescribed. It is projected that most people newly history of death related to coronary heart disease, nonfatal
diagnosed with hypertension according to the updated criteria myocardial infarction, or fatal/nonfatal stroke—when deciding
would fall into the Stage 1 hypertension category, for which whether to prescribe nonpharmacologic therapies, medica-
nonpharmacologic lifestyle interventions and counseling only tions, or both (see Figure 1). The risk estimation developed by
are recommended as treatment. An accurate diagnosis the ACC/AHA estimates the 10-year risk of atherosclerotic
should be based on an average of two or more blood pressure cardiovascular disease, with low risk defined as less than
readings obtained on two or more occasions to estimate an 10% and high risk defined as greater than 10%. Clinicians can
individual’s blood pressure category. use online risk estimators, such as that provided by the ACC
(see http://tools.acc.org/ASCVD-Risk-Estimator-Plus/
Accurate Blood Pressure Measurement #!/calculate/estimate). Information that is used to estimate
Accurate blood pressure measurement is critical to properly this risk includes age, sex, race, cholesterol (total and high-
categorize blood pressure and identify risk of hypertension. density lipoproteins), blood pressure, antihypertensive

348 Volume 22 Issue 4 doi: 10.1016/j.nwh.2018.06.003


Katigbak & Fontenot

FIGURE 1 BLOOD PRESSURE THRESHOLDS AND RECOMMENDATIONS FOR TREATMENT AND


FOLLOW-UP

Note. From “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood
Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines,” by P. K. Whelton, R. M.
Carey, W. S. Aronow, D. E. Casey Jr., K. J. Collins, C. Dennison Himmelfarb, . J. T. Wright Jr., 2018, Hypertension, 71, 1269–1324, doi:10.1161/
HYP.0000000000000066. ª 2017 American Heart Association, Inc. Reprinted with permission. ASCVD ¼ atherosclerotic cardiovascular disease; BP ¼ blood
pressure; CVD ¼ cardiovascular disease; mo ¼ month; y ¼ year.

medication use, diabetes status, and smoking status (Goff their blood pressure, and to make appropriate treatment rec-
et al., 2014). Using a risk-based approach focuses treatment ommendations. A combination of lifestyle changes and anti-
on those who are more likely to have cardiac events, thereby hypertensive medications is essential to lowering blood
reducing cardiovascular risk and preventing cardiovascular pressure and decreasing risk of atherosclerotic cardiovascular
events (Carey et al., 2018). disease. The target blood pressure for adults with a confirmed
hypertension diagnosis is less than 130/80 mm Hg. Primary
Treatment cardiovascular disease prevention through nonpharmacologic
therapy is recommended for adults at low risk (e.g., those with
Lifestyle Changes elevated blood pressure or Stage 1 hypertension with low
Clinicians are encouraged to work with individuals to assess atherosclerotic cardiovascular disease risk [<10% 10-year
and evaluate their cardiovascular risk, accurately classify risk]), with follow-up within 3 to 6 months of instituting lifestyle

August 2018 Nursing for Women’s Health 349


New Hypertension Guideline

BOX 1 EXAMPLES OF RESOURCES


AVAILABLE FROM “TARGET:BP”
Clinician Resources
 Blood Pressure Positioning Challenge: Resolve
Positioning Issues to Get an Accurate Reading
 Technique Quick Check: Checklist to ensure that blood
pressure readings are accurate
 Collaborative Communication Strategies to Manage
Blood Pressure
Patient Resources
 7-Day Blood Pressure Recording Log (2 times/day—
average)
 How Do I Manage My Medicines?
 Why Should I Limit Sodium?

Note. Resources can be accessed at https://targetbp.


org/tools-downloads.

changes. The treatment algorithm depicted in Figure 1 illustrates


recommendations for treatment and follow-up according to the
various blood pressure classifications.
The guideline emphasizes early detection of high blood
pressure and instituting nonpharmacologic lifestyle interventions
such as losing weight, increasing physical activity, moderating
alcohol consumption, and quitting smoking. Implementing these
lifestyle changes is known to reduce systolic blood pressure by 4
to 5 mm Hg and diastolic blood pressure by 2 to 4 mm Hg
(Cornelissen & Smart, 2013; Neter, Stam, Kok, Grobbee, &
Geleijnse, 2003; Roerecke et al., 2017; S. P. Whelton et al.,
2002; Xin et al., 2001). Dietary changes, however, such as
consuming less sodium, saturated fat, and total fat and more Women with moderately elevated
fruits, vegetables, and whole grains may decrease systolic blood
pressure by as much as 11 mm Hg (Aburto et al., 2013; Appel
blood pressure during pregnancy
et al., 2003; He, Li, & Macgregor, 2013; P. K. Whelton et al., have about twice the odds of
1997). Strategies for applying these interventions includes using developing hypertension later in life
a team-based approach composed of various providers (e.g.,
physicians, nurses, nurse practitioners, registered dietitians,
pharmacists, and social workers), using telemedicine, and lifestyle changes should be implemented, along with antihy-
encouraging use of health information technology for self- pertensive drug therapy using two drugs from different clas-
monitoring and increased engagement in self-care. ses. Prompt initiation of antihypertensive medication using
dual therapy should occur in patients with Stage 2 hyperten-
Pharmacologic Treatment
Photo ª KatarzynaBialasiewicz / iStockphoto.com

sion whose blood pressure is 160/100 mm Hg or greater.


Antihypertensive medication is recommended for adults with Additional recommendations include close monitoring and
Stage 1 hypertension (systolic blood pressure $130 mm Hg upward dose adjustment as necessary to control blood pres-
or diastolic blood pressure $80 mm Hg), no cardiovascular sure (see Table 2).
disease history, and high atherosclerotic cardiovascular dis-
ease risk ($10% 10-year risk). Lifestyle changes are also General Guidance on Drug Therapy
recommended, and a repeat blood pressure measurement The following summarizes the broad recommendations for
should be performed within 1 month. For adults with Stage 2 pharmacologic treatment; comprehensive information related
hypertension (systolic blood pressure $140 mm Hg or dia- to specific drugs and special populations can be found in the
stolic blood pressure $90 mm Hg), no cardiovascular disease article by P. K. Whelton et al. (2018). First-line initial therapy
history, and low atherosclerotic cardiovascular disease risk, for Stage 1 hypertension includes the use of thiazide

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Katigbak & Fontenot

TABLE 2 SUMMARY OF TREATMENT RECOMMENDATIONS BY BLOOD PRESSURE CATEGORY


Blood Pressure Category Treatment and Recommendations
Normal Yearly evaluation, promote healthful lifestyle changes to maintain normal BP
 Systolic blood pressure < 120 mm Hg and
 Diastolic blood pressure < 80 mm Hg
Elevated Promote health lifestyle change and re-evaluate in 3–6 months
 Systolic blood pressure 120–129 mm Hg and
 Diastolic blood pressure < 80 mm Hg
Stage 1 hypertension Assess 10-year risk for heart disease and stroke (e.g., ASCVD risk calculator)
 Systolic blood pressure [ 130–139 mm Hg  If ASCVD risk < 10%:
or diastolic blood pressure [ 80–89 mm Hg B Recommend healthful lifestyle changes and re-evaluate in 3–6 months

 If ASCVD risk > 10% with comorbidities:


B Recommend healthful lifestyle changes and one blood pressure–lowering
medication, then reassess in 1 month
B If blood pressure goal is met in 1 month: reassess in 3–6 months
B If blood pressure goal is not met in 1 month: titrate medication, or switch
B Monthly follow-up until blood pressure goal is met
Stage 2 hypertension Recommend healthful lifestyle changes and initiate antihypertensive drug
 Systolic blood pressure ‡ 140 mm Hg or therapy using two drugs from different classes
diastolic blood pressure ‡ 90 mm Hg B If blood pressure goal is met in 1 month: reassess in 3–6 months

B If blood pressure goal is not met in 1 month: titrate medication, or switch

B Monthly follow-up until blood pressure goal is met

 Systolic blood pressure ‡ 160 mm Hg or Promptly treat, monitor, and titrate medications for better blood pressure control.
diastolic blood pressure ‡ 100 mm Hg B Reassess blood pressure, document adherence and response to therapy,

reinforce importance of treatment and adherence, and screen for


orthostatic (or white coat) hypertension.
Note. ASCVD ¼ atherosclerotic cardiovascular disease.

diuretics, calcium channel blockers, angiotensin-converting thresholds for initiating drug therapy or recommendations on
enzyme inhibitors, or angiotensin receptor blockers, with a selecting medications to lower blood pressure, because no sig-
blood pressure goal of less than 130/80 mm Hg. Dosages nificant between-sex differences were identified by the guideline
should be titrated accordingly, and additional agents may be authors through their review of the literature.
added to the treatment regimen to achieve target blood Specific recommendations, however, are provided for
pressure. For adults with Stage 2 hypertension, two first-line treating hypertension during pregnancy. Women with hyper-
drugs from different classes are recommended (separately or tension who are pregnant or planning to become pregnant
combined as a fixed dose) when the average systolic blood should be transitioned to methyldopa, nifedipine, or labetalol
pressure and diastolic blood pressure are more than (P. K. Whelton et al., 2018). Conversely, during preconception
20 mm Hg and more than 10 mm Hg, respectively, greater and pregnancy, health care providers should not prescribe
than the target blood pressure. Follow-up should occur on a antihypertensive medications from the following drug classes:
monthly basis to monitor for treatment response and adher- angiotensin-converting enzyme inhibitors, angiotensin recep-
ence, and the medication dose should be titrated until blood tor blockers, or direct renin inhibitors (P. K. Whelton et al.,
pressure control is achieved. 2018), which are associated with adverse fetal outcomes;
these medications should be avoided in all women of repro-
ductive age (American College of Obstetricians and
Implications for Women’s Health Gynecologists, 2013).
Before age 50 years, hypertension prevalence is lower among
women than men, but women’s risk increases with age (Benjamin
et al., 2018). Despite evidence that hypertension prevalence in- Implications for Nursing Practice
creases among women with age, the new guideline does not The new guideline presents unique ways for nurses and
provide sex-based recommendations for treatment targets or advanced practice nurses to become more actively involved in

August 2018 Nursing for Women’s Health 351


New Hypertension Guideline

Association and the Amer-


ican Society for Preventive
Cardiology, others such as
the American Association of
Family Physicians and the
American College of Physi-
cians have declined to
endorse the guideline. There
is controversy around a num-
ber of factors, including the
increased number of people
who would be classified as
hypertensive, the potential
that greater pharmacologic
treatment will be enacted
without considering individual
risk status, potential
increased profits for the
pharmaceutical industry, and
the notion that the new blood
pressure thresholds may
lead to less individualized
care planning for varying de-
grees of hypertension (Bakris
& Sorrentino, 2018; Darrah,
2018).

preventing and treating high blood pressure in women. Nurses Conclusion


play a critical role in disease prevention by assessing for risk With the first comprehensive update to hypertension man-
and providing education and counseling, and they are ideally agement guidance in more than 10 years, authors of a new
positioned to screen for blood pressure and to initiate thera- ACC/AHA guideline recommend an aggressive approach to
peutic options at any point in a woman’s life span. preventing and managing hypertension. The new, lower
Although hypertension rates increase for women as they threshold that defines hypertension increases the number of
age, it is important for nurses to educate, screen, and treat U.S. adults who will be classified as having hypertension, and
blood pressure abnormalities in adolescent and young adult the guideline authors emphasize the importance of non-
women as well. According to Zang and Moran (2017), pharmacologic lifestyle interventions to prevent hypertension
approximately 7% of U.S. young adults ages 18 to 39 years disease progression. This new guidance promotes a holistic
have hypertension. Abnormalities in blood pressure have approach to illness management that nurses are well poised
health implications for contraceptive decision making, pre- to undertake. In doing so, there is great potential to address
conception counseling, and pregnancy. the long-standing public health issue of cardiovascular dis-
Pregnancy in particular can be a window of opportunity ease and to improve outcomes for women with hypertension
for behavior and lifestyle changes. Nurses can counsel across various stages of the life span. NWH
women about associated health implications of hyperten-
sion on imminent maternal/fetal health and health later in
life. It is important to facilitate and support lifestyle in-
terventions and referrals for exercise and/or nutrition
counseling for all young women. Women need to be aware
that if they have moderately elevated blood pressure during References
Photo ª kali9 / iStockphoto.com

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Katigbak & Fontenot

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