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ABSTRACT: Hypertension is a leading risk factor for the development of cardiovascular disease. In 2017, the American College of
Cardiology and the American Heart Association published a new guideline for the prevention, detection, evaluation, and management
of hypertension. The guideline adjusts the clinical parameters for diagnosis and management of hypertension. In this article we
summarize the updates and provide some background on these changes as they relate to nursing practice implications, with specific
implications for women’s health.
doi: 10.1016/j.nwh.2018.06.003 Accepted May 2018
KEYWORDS: blood pressure, cardiovascular disease, guideline, hypertension, pre-hypertension, Stage 1 hypertension, Stage 2
hypertension, stroke
Photo ª geckophotos / iStockphoto.com
U
ncontrolled hypertension is a critical modifiable risk condition under control (Yoon, Fryar, & Carroll, 2015),
factor in the development and progression of a increasing their risk for cardiovascular disease and stroke. For
number of conditions, including cerebrovascular women, cardiovascular disease is the leading cause of death,
disease and cardiovascular disease. Approximately 75 million accounting for one out of every three female deaths (Garcia,
Americans, or one third of the U.S. adult population, have high Mulvagh, Merz, Buring, & Manson, 2016). Epidemiologic
blood pressure (Centers for Disease Control and Prevention, evidence shows that although hypertension prevalence is
2016), and only slightly more than half (54%) of them have the lower among adult women compared with men from ages 18
CLINICAL IMPLICATIONS
n Uncontrolled hypertension is a critical modifiable risk factor in the
development and progression of cerebrovascular disease and
cardiovascular disease.
n The American College of Cardiology and the American Heart
Association have released a new guideline for the prevention,
detection, evaluation, and management of hypertension.
n The new guideline emphasizes early detection of high blood
pressure and adoption of nonpharmacologic lifestyle
interventions such as losing weight, increasing physical activity,
moderating alcohol consumption, and quitting smoking.
n Nurses play a critical role in disease prevention by assessing for
risk and providing education and counseling.
n Nurses are ideally positioned to screen for high blood pressure
and to initiate therapeutic options at any point in a woman’s life
span.
practice guideline (P. K. Whelton et al., 2018). A team of the blood pressure threshold for defining hypertension, and
multidisciplinary experts oversaw four systematic reviews recategorizes blood pressure into normal, elevated, Stage 1
hypertension, and Stage 2 hypertension. Shared decision
making between providers and patients and team-based care
Carina Katigbak, PhD, RN, ANP-BC, is an assistant professor, William F. are further emphasized in terms of establishing an evidence-
Connell School of Nursing at Boston College in Chestnut Hill, MA. Holly B.
based plan of care that incorporates self-management, timely
Fontenot, PhD, RN, WHNP-BC, is an associate professor, William F. Connell
School of Nursing at Boston College in Chestnut Hill, MA. The authors report
follow-up, home-based blood pressure monitoring, and greater
no conflicts of interest or relevant financial relationships. Address attention to lifestyle interventions to prevent disease
correspondence to: katigbac@bc.edu. progression.
Blood Pressure Classification The new guideline provides seven tips for health care pro-
The most impactful change in the new guideline is the new viders to accurately measure blood pressure. Improper patient
definition and reclassification of stages of high blood pres- preparation (e.g., not emptying bladder, caffeine consumption
sure. A normal blood pressure, as defined by both the JNC7 before measurement), improper patient positioning, and
and the new guideline, remains less than 120/80 mm Hg. inappropriate cuff size/cuff placement all can lead to inac-
Prehypertension is reclassified into two new categories: curate blood pressure measurements with inaccuracies
elevated blood pressure (120–129/<80 mm Hg) and Stage 1 ranging from 5 to 50 mm Hg (Kallioinen, Hill, Horswill, Ward, &
hypertension (130–139 mm Hg systolic pressure or 80– Watson, 2017; Ringrose, Wong, Yousefi, & Padwal, 2017;
89 mm Hg diastolic pressure), effectively lowering the Ozone et al., 2016).
threshold by which clinicians diagnose hypertension to The new guideline recommends out-of-office/home-based
130 mm Hg or greater systolic blood pressure and 80 mm Hg blood pressure measurement and self-monitoring to confirm
or greater diastolic blood pressure. Stage 2 hypertension is hypertension diagnosis when an elevated blood pressure has
classified as 140/90 mm Hg or greater (see Table 1). been detected in health care settings and to guide titration of
The rationale for these new definitions is based on evi- blood pressure–lowering medication; or alternately, to screen
dence from several meta-analyses in which researchers re- for white coat hypertension or masked hypertension before
ported a gradient in cardiovascular disease risk that rises as providing a diagnosis of hypertension. Providers must educate
blood pressure increases from normal to elevated to hyper- and work with patients on proper at-home blood pressure
tension (Guo, Zhang, Guo, et al., 2013; Guo, Zhang, Zheng, measurement techniques and documentation practices.
et al., 2013; Huang et al., 2014; Shen, Ma, Xiang, & Wang, Numerous tools and resources are available for providers and
2013), in addition to observational data (Lewington et al., patients to use toward achieving blood pressure goals, such
2002) and randomized trials of lifestyle interventions to lower as “Target:BP” (2016), a recent collaboration between the
blood pressure (S. P. Whelton, Chin, Xin, & He, 2002). As AHA and American Medical Association that provides free
systolic blood pressure exceeds 120 mm Hg, cardiovascular online resources for clinicians and patient tools such as self-
disease risk increases, and this risk doubles with systolic care tips and checklists for at-home blood pressure moni-
blood pressure of 130 mm Hg or greater. toring to promote engaged decision making (see Box 1).
This change to the definition of hypertension substantially
increases the proportion of U.S. adults with hypertension from Risk-Based Treatment Approach
one third to one half of the U.S. adult population (Muntner The new guideline includes a risk-based approach to treat-
et al., 2018). However, this growth in newly diagnosed hy- ment. The authors recommend that health care providers
pertension cases translates to a small increase (1.9%) in the consider an individual’s risk for experiencing events related to
number of U.S. adults for whom antihypertensive medications atherosclerotic cardiovascular disease—defined as family
would be prescribed. It is projected that most people newly history of death related to coronary heart disease, nonfatal
diagnosed with hypertension according to the updated criteria myocardial infarction, or fatal/nonfatal stroke—when deciding
would fall into the Stage 1 hypertension category, for which whether to prescribe nonpharmacologic therapies, medica-
nonpharmacologic lifestyle interventions and counseling only tions, or both (see Figure 1). The risk estimation developed by
are recommended as treatment. An accurate diagnosis the ACC/AHA estimates the 10-year risk of atherosclerotic
should be based on an average of two or more blood pressure cardiovascular disease, with low risk defined as less than
readings obtained on two or more occasions to estimate an 10% and high risk defined as greater than 10%. Clinicians can
individual’s blood pressure category. use online risk estimators, such as that provided by the ACC
(see http://tools.acc.org/ASCVD-Risk-Estimator-Plus/
Accurate Blood Pressure Measurement #!/calculate/estimate). Information that is used to estimate
Accurate blood pressure measurement is critical to properly this risk includes age, sex, race, cholesterol (total and high-
categorize blood pressure and identify risk of hypertension. density lipoproteins), blood pressure, antihypertensive
Note. From “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood
Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines,” by P. K. Whelton, R. M.
Carey, W. S. Aronow, D. E. Casey Jr., K. J. Collins, C. Dennison Himmelfarb, . J. T. Wright Jr., 2018, Hypertension, 71, 1269–1324, doi:10.1161/
HYP.0000000000000066. ª 2017 American Heart Association, Inc. Reprinted with permission. ASCVD ¼ atherosclerotic cardiovascular disease; BP ¼ blood
pressure; CVD ¼ cardiovascular disease; mo ¼ month; y ¼ year.
medication use, diabetes status, and smoking status (Goff their blood pressure, and to make appropriate treatment rec-
et al., 2014). Using a risk-based approach focuses treatment ommendations. A combination of lifestyle changes and anti-
on those who are more likely to have cardiac events, thereby hypertensive medications is essential to lowering blood
reducing cardiovascular risk and preventing cardiovascular pressure and decreasing risk of atherosclerotic cardiovascular
events (Carey et al., 2018). disease. The target blood pressure for adults with a confirmed
hypertension diagnosis is less than 130/80 mm Hg. Primary
Treatment cardiovascular disease prevention through nonpharmacologic
therapy is recommended for adults at low risk (e.g., those with
Lifestyle Changes elevated blood pressure or Stage 1 hypertension with low
Clinicians are encouraged to work with individuals to assess atherosclerotic cardiovascular disease risk [<10% 10-year
and evaluate their cardiovascular risk, accurately classify risk]), with follow-up within 3 to 6 months of instituting lifestyle
Systolic blood pressure ‡ 160 mm Hg or Promptly treat, monitor, and titrate medications for better blood pressure control.
diastolic blood pressure ‡ 100 mm Hg B Reassess blood pressure, document adherence and response to therapy,
diuretics, calcium channel blockers, angiotensin-converting thresholds for initiating drug therapy or recommendations on
enzyme inhibitors, or angiotensin receptor blockers, with a selecting medications to lower blood pressure, because no sig-
blood pressure goal of less than 130/80 mm Hg. Dosages nificant between-sex differences were identified by the guideline
should be titrated accordingly, and additional agents may be authors through their review of the literature.
added to the treatment regimen to achieve target blood Specific recommendations, however, are provided for
pressure. For adults with Stage 2 hypertension, two first-line treating hypertension during pregnancy. Women with hyper-
drugs from different classes are recommended (separately or tension who are pregnant or planning to become pregnant
combined as a fixed dose) when the average systolic blood should be transitioned to methyldopa, nifedipine, or labetalol
pressure and diastolic blood pressure are more than (P. K. Whelton et al., 2018). Conversely, during preconception
20 mm Hg and more than 10 mm Hg, respectively, greater and pregnancy, health care providers should not prescribe
than the target blood pressure. Follow-up should occur on a antihypertensive medications from the following drug classes:
monthly basis to monitor for treatment response and adher- angiotensin-converting enzyme inhibitors, angiotensin recep-
ence, and the medication dose should be titrated until blood tor blockers, or direct renin inhibitors (P. K. Whelton et al.,
pressure control is achieved. 2018), which are associated with adverse fetal outcomes;
these medications should be avoided in all women of repro-
ductive age (American College of Obstetricians and
Implications for Women’s Health Gynecologists, 2013).
Before age 50 years, hypertension prevalence is lower among
women than men, but women’s risk increases with age (Benjamin
et al., 2018). Despite evidence that hypertension prevalence in- Implications for Nursing Practice
creases among women with age, the new guideline does not The new guideline presents unique ways for nurses and
provide sex-based recommendations for treatment targets or advanced practice nurses to become more actively involved in
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