RUHS Recruitment

Examination 2021  
Question  Paper
ADA Recruitment 2021
Q. No. 1
The vaccination drive started against COVID 19 in India
0012001

Option A January 16, 2021

Option B January 16, 2020

Option C February 16, 2021

Option D February 16 2020

Correct Option A

Q. No. 2
The full form of MALDI is
0012002
Option A Matrix-assisted laser desorption ionization

Option B Metal-assisted laser desorption ionization

Option C Molecule-assisted desorption ionization

Option D Macromolecule-assisted laser desorption ionization

Correct Option A

Q. No. 3 Minimum space required for retail drug store as per Drug and Cosmetic Act and Rules
0012003 1945
Option A 10 square meter
Option B 15 square meter

Option C 108 square meter

Option D 100 square meter

Correct Option A

Q. No. 4
Blood smear is best seen at pH of

0012004
Option A 7.2

Option B 6.8

Option C 6.6

Option D 7.0

Correct Option B

Q. No. 5
The hard gelatin capsule contains moisture
0012005

Option A 15-20%

Option B 9-12%

Option C 25-30%

Option D 2-5%

Correct Option B

Q. No. 6 Emulsions having an aqueous internal phase and an oleaginous external phase are
0012006 termed
Option A Water-in-oil emulsions

Option B Oil-in-water emulsions

Option C Water-in-oil-in-water emulsions

Option D Oil-in-water-in-oil emulsions

Correct Option A

Q. No. 7
The surface active agents having HLB value in the range 3-6 can be considered as

0012007

Option A o/w Emulsifiers

Option B w/o Emulsifiers

Option C Solubilizers

Option D Detergents

Correct Option B

Q. No. 8
Povidone-Iodine (I.P) contains
0012008
Option A Not less than 9.0 percent and not more than 12.0 percent of available iodine

Option B Not less than 2.0 percent and not more than 6.0 percent of available iodine

Option C Not less than 14.0 percent and not more than 18.0 percent of available iodine

Option D Not less than 20.0 percent and not more than 25.0 percent of available iodine

Correct Option A

Q. No. 9
Which substance is essential for vitamin D metabolism?
0012009

Option A Parathormone

Option B Calcitonin

Option C Thyroxin
Option D Growth hormone

Correct Option A

Q. No. 10
Vaccines are sterilised by

0012010
Option A Seitz filtration

Option B Hot air oven

Option C Autoclaving

Option D Heat inactivation

Correct Option A

Q. No. 11 The study of absorption, distribution, metabolism and elimination of drug in the body
0012011 is known as

Option A Pharmacodynamics

Option B Pharmacokinetics

Option C Pharmacotherapy

Option D Phamacognosiaytic cycle

Correct Option B

Q. No. 12 Enzyme appearing early in myocardial infraction

0012012

Option A CPK

Option B LDH
Option C SGOT

Option D SGPT

Correct Option A

Q. No. 13 I.P prescribes the concentration of active ingredient in of chloramphenicol eye

0012013 ointment

Option A 2%w/w

Option B 1% w/w

Option C 3% w/w

Option D 2.5% w/w

Correct Option B

Q. No. 14
Enzyme deficient in diabetes mellitus is
0012014

Option A Glucokinase

Option B Hexokinase

Option C Phosphorylase
Option D Pyrophosphate dehydrogenase

Correct Option A

Q. No. 15
Pyridoxine deficiency can cause all except

0012015

Option A Convulsion in infants

Option B Anaemia

Option C Peripharal neuritis

Option D Growth retardation

Correct Option D

Q. No. 16
Aqueous iodine solution oxidises ascorbic acid (I.P) in
0012016
Option A Dimethyl ascorbic acid

Option B Dehydro ascorbic acid

Option C L-thrionic acid

Option D Oxalic acid and L- thrionic acid both

Correct Option B

Q. No. 17 Which primary standard is most suitable to standardise 0.1 M tetrabutyl ammonium
0012017 hydroxide used to estimate very weak acids innonaqueous titration?

Option A Benzoic acid

Option B Perchloric acid

Option C Oxalic acid

Option D 0.1 N Hydrochloric acid

Correct Option A


Q. No. 18
Glutathione is a tripeptide of
0012018

Option A Glu- Cys- Gly

Option B Leu-Gly-Glu

Option C Phe-Pro-Cys

Option D Glu-Cys-Tyr

Correct Option A

Q. No. 19 Ampicillin(I.P) gives mercuric mercaptide when acetylated by acetic anhydride in

0012019 alkaline borate buffer (pH 9.0) followed by the reaction with imidazole mercury
reagent in water bath at 60oC and can be measured at 325nm. Choose the correct
structure of compound that is measured at 325nm

Option A

Option B

Option C
Option D

Correct Option A

Q. No. 20
Which one is the active metabolite of Clopidrogrel(I.P)?
0012020

Option A

Option B

Option C

Option D
Correct Option D

Q. No. 21
The assay of Benzocaine (I.P) is based on
0012021

Option A Redox titration

Option B Sodium nitrite titration

Option C Complexometric titration

Option D Nonaquous titration

Correct Option B

Q. No. 22
The complete hydrolysis of oxytocin gives
0012022

Option A 12 different amino acids

Option B 08 different amino acids

Option C 09 different amino acids

Option D 10 different amino acids

Correct Option B

Q. No. 23
Therapeutic index of a drug is an indicator of
0012023

Option A Safety

Option B Potency

Option C Action

Option D Efficacy

Correct Option A

Q. No. 24
Calamine lotion contains
0012024

Option A Calcium oxide and Calamine

Option B Lead oxide and Calamine

Option C Zinc oxide and Calamine

Option D Magnesium oxide and Calamine

Correct Option C

Q. No. 25
The parent drug of Canrenone is
0012025

Option A Spironolactone (I.P)

Option B Furosemide (I.P)

Option C Acetazolamide (I.P)

Option D Ethacrynic acid (I.P)

Correct Option A

Q. No. 26
Zwitter ions have
0012026

Option A +ve ions > -ve ions

Option B +ve ions < -ve ions

Option C +ve ion << -ve ion

Option D +ve ion = -ve ion

Correct Option D

Q. No. 27
At the physiological pH the DNA molecules are
0012027

Option A Positively charged

Option B Negatively charged

Option C Neutral

Option D Amphipathic

Correct Option B

Q. No. 28
The buffering capacity of a buffer is maximum at pH equal to
0012028

Option A 0.5 pKa

Option B pKa

Option C pKa+1

Option D 2pKa

Correct Option B

Q. No. 29
Michaelis -Menten hypothesis states that
0012029

Option A Rate of enzymatic reaction is independent of substrate concentration

Option B Rate of non-enzymatic reaction is proportional to substrate concentration

Option C Km is the enzyme-substrate complex association constant

Option D Enzyme-substrate complex formation is essential in enzymatic reaction

Correct Option D

Q. No. 30
Infant's gastric juice pH is
0012030

Option A 1.4

Option B 2.1

Option C 5.0

Option D 7.0

Correct Option C

Q. No. 31
pH of normal sweat is
0012031

Option A 1.2

Option B 4.5
Option C 7.4

Option D 9.1

Correct Option B

Q. No. 32
Most important buffer in RBC is
0012032

Option A O2Hb+ Na Hemoglobinate

Option B O2Hb+ KHemoglobinate

Option C H2CO3+KHCO3

Option D H2CO3+NaHCO3

Correct Option B

Q. No. 33
A vitamin which functions as reducing agent
0012033

Option A B12

Option B Vitamin C

Option C Nicotianamide

Option D Folate

Correct Option B

Q. No. 34
Thiamine is essential for
0012034

Option A Pyruvate dehydrogenase

Option B Isocitrate dehydrogenase

Option C Succinate dehydrogenase

Option D Acetyl CoA synthetase

Correct Option A

Q. No. 35
Which vitamin prevents peroxidation of lipids on cellular level?
0012035

Option A Vitamin A

Option B Vitamin C

Option C Vitamin E

Option D Vitamin K

Correct Option C

Q. No. 36
NMR is based on
0012036

Option A Nuclear fission

Option B Charge of nucleus

Option C Magnetic moment of nucleus

Option D Electrical moment of nucleus

Correct Option C

Q. No. 37
The images are observed in NMR scan due to
0012037

Option A Proton density

Option B Electron density

Option C Neutron density

Option D Positron density

Correct Option A

Q. No. 38 Choose the correct range of C=O stretch of normal aliphatic aldehyde in Infrared
0012038 spectroscopy

Option A 1700-1660 cm-1

Option B 1700-1660 cm-1

Option C 1600-1450 cm-1

Option D 1740-1725 cm-1

Correct Option D

Q. No. 39 Choose the correct range of C=O stretch of normal aliphatic ester in Infrared
0012039 spectroscopy

Option A 1750-1735cm-1

Option B 1600-1450cm-1

Option C 1740-1715cm-1

Option D 1765-1762cm-1

Correct Option A

Q. No. 40 Generally hydrogen attached to an amide nitrogen (R-CO-NH-), the chemical shift
0012040 observed in 1H NMR at

Option A 5.0-9.0 ppm

Option B 2.1-2.5 ppm

Option C 2.2-2.9 ppm

Option D 4.1-4.4 ppm

Correct Option A

Q. No. 41 An oligopeptide obtained by tryptic digestion was investigated by an ion trap MS-MS
0012041 and gave Ion trap data as 146, 203, 260,357,444, 591, 648, 705, 802, 890. What
would be the average molecular mass?

Option A 890 Da

Option B 889 Da

Option C 891 Da

Option D 892 Da

Correct Option B

Q. No. 42
Most abundant ion peak in mass spectra is
0012042

Option A Molecular ion peak

Option B Base peak

Option C Daughter ion peak

Option D precursor ion peak

Correct Option B


Q. No. 43
In Q-TOF LC MS, TOF stands for
0012043

Option A Target of fragment

Option B Test of fragment

Option C Time of flight

Option D Target of flight

Correct Option C

Q. No. 44
Column length in GC is
0012044

Option A Less than 100mm

Option B More than 10mm but less than 100 cm

Option C More than 100 cm but less than 500 cm

Option D More than 5 meter

Correct Option D

Q. No. 45
Derivatization techniques in HPLC are intended to enhance
0012045

Option A Molecular weight

Option B Detectability

Option C Reversibility

Option D Reproducibility

Correct Option B

Q. No. 46
The nature of stationary phase in reverse phase chromatography remains
0012046

Option A Non polar

Option B Polar

Option C Polar and non-polar both

Option D Depend upon the nature of analyte

Correct Option A

Q. No. 47 Which of the following will increase the efficiency of separation process in liquid
0012047 chromatography?

Option A Increase in sample size, increase in column diameter

Option B Reduction in sample size, increase in column diameter

Option C Increase in sample size, reduction in column diameter

Option D Reduction in sample size, reduction in column diameter

Correct Option D

Q. No. 48
The adsorption mechanism of silica gel involves
0012048

Option A Interaction of solute with acidic silanol group

Option B Interaction of solute with basic silanol group

Option C Interaction of solute with neutral silanol group

Option D Interaction of solute with inert silane group

Correct Option A

Q. No. 49
Which component will elute first in reverse phase HPLC
0012049

Option A Non polar

Option B Polar

Option C High molecular weight

Option D Low molecular weight

Correct Option B

Q. No. 50
M+1 peak occurs for which type of isotopes?
0012050

Option A 18O

Option B 13C

Option C 34
S

Option D 81
Br

Correct Option B

Q. No. 51 According to Drugs and cosmetic rules 1945, which form is required for application
0012051 for licence to import drugs for the purpose of examination, test and analysis?

Option A Form 12

Option B Form 13
Option C Form 12-B

Option D Form 14-B

Correct Option A

Q. No. 52
The Chairman of Drug Technical Advisory Board (DTAB) is
0012052
Option A The President, Pharmacy Council of India (PCI)
Option B The Drugs Controller General of India (DCGI)

Option C The Director General of Health Services

Option D The Director, Central Drugs Laboratory (CDL) Kolkata

Correct Option C

Q. No. 53
"Spurious drugs" can be defined
0012053

Option A If it is manufactured under a name which belongs to another drug

Option B If it contains a colour which is not prescribed

Option C If any substance has been mixed there with so as to reduce its quality or strength
Option D If it contains any harmful or toxic substance which may render it injurious to health

Correct Option A

Q. No. 54 Licence to sell, stock or exhibit for sale or distribute by retail drugs specified in
0012054 schedule C and C (1) is given in form number

Option A 19
Option B 21
Option C 18

Option D 24
Correct Option B

Q. No. 55 In Drugs and Cosmetic Acts and Rules there under, Good Laboratory Practices (GLP),
0012055 requirements of premises and equipment are given in
Option A Schedule J

Option B Schedule M

Option C Schedule L

Option D Schedule O

Correct Option C

Q. No. 56 In Drugs and Cosmetic Acts and Rules there under, standards for ophthalmic
0012056 preparations are given in
Option A Schedule F
Option B Schedule FF

Option C Schedule X
Option D Schedule L

Correct Option B

Q. No. 57
As per the drugs and cosmetic act and rules, list of prescription drugs is given in
0012057

Option A Schedule H
Option B Schedule J

Option C Schedule F
Option D Schedule M

Correct Option A

Q. No. 58 In which schedule "biological products" are enlisted under Drugs and Cosmetic Acts
0012058 and rule

Option A Schedule C
Option B Schedule D

Option C Schedule M
Option D Schedule J

Correct Option A

Q. No. 59 In drugs and cosmetic act and rules, standards for patent or proprietary medicines
0012059 are mentioned in
Option A Schedule V

Option B Schedule R
Option C Schedule R-1

Option D Schedule O
Correct Option A

Q. No. 60
The clinical trial means
0012060
Option A Systematic study of new drugs in human subjects
Option B Systematic study of new drugs in animal subjects

Option C Systematic study of new drugs neither in human nor animals

Option D Systematic study of new drugs in both human and animal subjects
Correct Option A

Q. No. 61
Weight variation limit as per USP for the tablet weight more than 324 mg is
0012061
Option A 7.5 mg

Option B 7.5%
Option C 5%

Option D 5.0 mg
Correct Option C

Q. No. 62
Lactose is used in tablet formulation as
0012062
Option A Lubricant

Option B Diluent
Option C Glidant

Option D Disintegrant
Correct Option B

Q. No. 63
As per the USP requirement, friability test limit ranges
0012063
Option A 0.5-1%
Option B 0.8-1%

Option C 1-2%
Option D 0.1-0.5%

Correct Option A

Q. No. 64 The time required to dissolve enteric coated tablet in 0.1 N HCl as per the I.P.
0012064 Standard is

Option A 180 minutes

Option B 120 minutes

Option C 45 minutes
Option D 60 minutes

Correct Option B

Q. No. 65
As per the I.P. standards, the disintegration time for sugar coated tablet is
0012065

Option A 15 minutes
Option B 30 minutes

Option C 60 minutes
Option D 90 minutes

Correct Option C

Q. No. 66 As per the I.P standard, temperature condition of disintegration test for normal size
0012066 tablets, bolues and capsules is
Option A

Option B

Option C

Option D

Correct Option C

Q. No. 67
Rotational speed of USP type-II dissolution apparatus is
0012067

Option A 10-15 rpm

Option B 25-50 rpm

Option C 50-120 rpm

Option D 75-100 rpm

Correct Option B

Q. No. 68
The degree of force required to crush a tablet is observed under
0012068

Option A Friability test

Option B Disintegration test

Option C Dissolution test

Option D Crushing strength test

Correct Option D

Q. No. 69
First step in the absorption of drug through a tablet dosage form is
0012069
Option A Disintegration

Option B Deaggregation
Option C Diffusion

Option D Dissolution
Correct Option A

Q. No. 70
Moisture and heat sensitive drugs are formulated into tablets by
0012070
Option A Direct compression

Option B Dry granulation

Option C Wet granulation

Option D Neither compression nor granulation

Correct Option B

Q. No. 71
Unequal distribution of colour in tablet dosage form is known as
0012071
Option A Capping

Option B Picking
Option C Mottling

Option D Lamination
Correct Option C

Q. No. 72 Stearic acid is used in the tablet formulation as

0012072
Option A Lubricant

Option B Glidant
Option C Binder

Option D Disintegrant
Correct Option A

Q. No. 73
An expectorant can be defined as
0012073

Option A A drug that increases respiratory tract secretion, lowers viscosity and promotes removal
Option B A drug that decrease respiratory tract secretion, increases viscosity and hinders removal

Option C A drug that induce vomiting

Option D A drug that promotes renal excretion of electrolyte and water

Correct Option A

Q. No. 74
The alcoholic or hydro alcoholic solutions of volatile substances is known as
0012074

Option A Tincture
Option B Syrup

Option C Spirit
Option D Water

Correct Option C

Q. No. 75
The unit of radioactivity is curie (Ci) defined as
0012075

Option A 3.700X1010 nuclear transformation per second

Option B 4.700X1010 nuclear transformation per second

Option C 5.700X1010 nuclear transformation per second

Option D 6.700X1010 nuclear transformation per second

Correct Option A

Q. No. 76
Which one is not classified under suppository bases?
0012076
Option A Fatty or Oleaginous bases

Option B Water soluble or water miscible bases

Option C Combination of lipophilic and hydrophilic substances
Option D Metals

Correct Option D

Q. No. 77
The oticor aural preparations are used in
0012077

Option A Eye
Option B Ear

Option C Nose
Option D Throat
Correct Option B

Q. No. 78
The physiological factor that affects the ocular bioavailability of a drug
0012078
Option A Only drug metabolism
Option B Only lachrymal drainage

Option C Only Protein binding

Option D Protein binding, drug metabolism and lachrymal drainage

Correct Option D

Q. No. 79 Which one is not a suitable concentration for preventing the growth of micro-
0012079 organism in eye preparations?

Option A Benzalkonium chloride 0.01%

Option B Benzalkonium chloride 0.01% with solutions of nitrate and salicylates

Option C Chlorobutanol 0.5%

Option D Phenyl ethyl alcohol 0.5%

Correct Option B

Q. No. 80
Magmas and gel represents
0012080

Option A Fine dispersion

Option B Course dispersion

Option C Colloidal dispersion

Option D Neither dispersion nor dispersion medium

Correct Option A

Q. No. 81
According to I.P., the concentration of standard Arsenic solution for limit test is
0012081
Option A 10 ppm As

Option B > 10 ppm As

Option C < 10 ppm As

Option D ~ 15 ppm As
Correct Option A

Q. No. 82
In the limit test of Iron, purple colour is produced due to the formation of
0012082
Option A Ferric thioglycollate coordination compound

Option B Ferrous thioglycollate coordination compound

Option C Thioglycolic acid itself

Option D Ferric ammonium citrate

Correct Option B

Q. No. 83
Permanganate solutions are often standardized against
0012083
Option A Oxalic acid

Option B Ferrous sulphate/Ferrous ammonium sulphate

Option C Ferric chloride
Option D Ferric oxides
Correct Option B

Q. No. 84 In acidic solution, each molecule of potassium dichromate (K2Cr2O7) provides

0012084
Option A Three oxygen atoms for oxidizing purposes

Option B Four oxygen atoms for oxidizing purposes

Option C Five oxygen atoms for oxidizing purposes

Option D Six oxygen atoms for oxidizing purposes

Correct Option A

Q. No. 85 Iodine, in presence of water, acts as a mild oxidizing agent and used for this purpose
0012085 in a variety of volumetric determinations. How many gramme equivalent of oxygen is
produced by each gram-atom of iodine?
Option A 1

Option B 2
Option C 3

Option D 1/2
Correct Option D

Q. No. 86
The ceric ammonium sulphate is
0012086

Option A Weak oxidizing agent

Option B Weak reducing agent

Option C Strong oxidizing agent

Option D Strong reducing agent

Correct Option C

Q. No. 87
The principle reaction involved in sodium nitrite titration is based on
0012087

Option A Diazotization
Option B Redox reaction

Option C Complex formation reaction

Option D Aquametric reaction

Correct Option A

Q. No. 88 The Thiamine Hydrochloride (I.P.) when treated with sodium hydroxide and
0012088 potassium ferrycyanide results intense light blue fluorescence due to formation of

Option A 4-methylthiazole-5-carboxylic acid

Option B 4-aminopyrimidine

Option C Thiochrome
Option D 4-amino-2,5-dimethylpyridine

Correct Option C

Q. No. 89
The commonly used detector in UV spectrophotometer is
0012089
Option A Littrow prisms
Option B Thermocouple

Option C Photomultiplier tube

Option D Bolometer

Correct Option C

Q. No. 90
The shift of an absorption maxima to a higher wavelength is known as
0012090

Option A Bathochromic shift

Option B Hyperchromic shift

Option C Hypsochromic shift

Option D Hypochromic shift

Correct Option A

Q. No. 91 When 1N NaOH is titrated against 1N HCl using phenolphthalein indicator, the pink
0012091 colour observed at the end point but next drop of HCl changes pink colour to
colourless because

Option A Phenolphthalein is not a suitable indicator for this titration

Option B Phenolphthalein is an acid insensitive indicator

Option C Phenolphthalein is insensitive to carbon dioxide

Phenolphthalein is sensitive to carbon dioxide as NaOH pallets contains some amount of
Option D
NaHCO3

Correct Option D

Q. No. 92
Platinum electrode is used for
0012092
Option A Acid base titration

Option B Conductometric titration

Option C Redox titration

Option D Non aqueous titration

Correct Option C

Q. No. 93
Calcium lactate (I.P.) is assayed by
0012093

Option A Non aqueous titration

Option B Complexometric titration

Option C Acid base titration

Option D Redox titration

Correct Option B

Q. No. 94
The titrant and indicator used in the assay of pyrazinamide (I.P.) is
0012094

Option A 0.1 M NaOH ,methyl red

Option B 0.1 M HCl, methyl red

Option C 0.1N Perchloric acid, crystal violet

Option D 0.1 M K2Cr2O7, starch

Correct Option A

Q. No. 95 Hydralazine hydrochloride(I.P.) and hydralazine injection(I.P.) are assayed by

0012095

Option A Potassium iodate titration

Option B Perchloric acid titration

Option C Sodium EDTA titration

Option D Sodium nitrite titration

Correct Option A

Q. No. 96
The detecting agent used to identify amino acid is
0012096

Option A Iodine
Option B Sulphuric acid

Option C Iodine vapour+Sulphuric acid

Option D Ninhydrin reagent

Correct Option D

Q. No. 97
0.1 N NaOH is used as titrant in the assay of following except
0012097
Option A Ibuprofen (I.P)

Option B Indomethacin (I.P)

Option C Glybenclamide (I.P)

Option D Calciumgluconate (I.P)

Correct Option D

Q. No. 98
Polarographic technique is based on the measurement of
0012098
Option A Potential difference

Option B Resistance
Option C Temprature change

Option D Conductivity
Correct Option A

Q. No. 99 Five measurements of fasting serum glucose concentration were made on the same
0012099 sample taken from a diabetic patient. The value obtained were 2.3, 2.5, 2.2, 2.6, and
2.5 mM. What would be the precision of the data set?
Option A 6.8%

Option B 10.0%
Option C 5.0%

Option D 2.0%
Correct Option A

Q. No. 100
The content of alcohol (I.P) is determined by
0012100
Option A Titration

Option B Derivatization
Option C Degradation

Option D Observing the relative density at 25oC

 Correct Option D