Master’s International School Academic Year :2021 – 2022

MIS Class: Grade 8

Department of Sciences Date:
C. Rafik Mroueh Duration: 60 minutes
Name: Biology Mid-term Exam Teacher: Sara Ezzeddine
Score: /15
Exercise 1 (5 pts.)
After a skin injury, changes are observed that take place only in the site of the injury. These changes are shown
in the document below:

1. According to your acquired knowledge, give the name of the immune reaction represented by document
1. (0.5 pt.)
2. Indicate the type of this immune response. (0.5 pt.)
3. Pick out from document 1:
3.1. A symptom of this immune reaction. (0.25 pt.)
3.2.A change that takes place in the blood capillaries. (0.25 pt.)
3.3.The name of the cells involved in this reaction. (0.25 pt.)
4. Figures 3 and 4 of this document show the defense mechanism produced by these cells to kill pathogens.
4.1.Give the name of this mechanism and define it. (1 pt.)
4.2.Name and describe the steps A, B and C of this mechanism shown schematically in figures 3 and 4. (1.5
pt.)
4.3.Arrange these steps in order. (0.75 pt.)
Exercise 2 (10 pts.)
The documents below present the results obtained upon testing two blood groups.

Anti-B + cells with Agglutinogen B Cells with Agglutinogen A + Anti-A

Case 1 Case 2
 1. Identify the blood group in the two cases. (2 pts.)
2. Tell whether the transfusion of case 1 is successful. Justify your answer. (1 pt.)
3. Give the name the immune cell involved in this reaction. (0.5 pts.)
4. If it is intended to make a blood transfusion for the person of case 2.
4.1. What is the applied rule in this case? (1 pt.)
4.2.What blood group can this person receive? Justify your answer. (1 pt.)
5. In case of rejection of blood transfusion.
5.1. Indicate the type of the immune response involved in this reaction. (0.5 a pt.)
5.2.Name of the reaction that occurs in this case. (0.5 a pt.)

A- The document below represents the action of a T lymphocyte on a foreign cell.

Two steps of the destruction of a foreign or infected cell by L.T.

Step 1 shows the binding of T-lymphocyte on the infected cell, while step 2 shows the perforation and
destroying of the infected cell.
1. Complete: (0.5 pt.)
The immune response performed by T-lymphocytes is a ................................................................
..................................................response.
2. The table below shows the variation of the number of foreign cells rejected as function of the number of
activated T lymphocytes.

Number of activated T lymphocytes (a.u) 0 3 6 9 12 15

Number of foreign cells rejected (a.u) 0 4 6 8 9 11

2.1. Convert this table into a graph. (1.5 pt.)

Scale : x'ox axis: 1cm → 3 a.u
Y'oy axis: 1cm → 2 a.u
2.2. Analyze the results obtained in the table. (1.5 pt.)
GOOD WORK