Pharmacology

Paper 3

~describe MOA of salbutamol, folmetarol, theophyline (list 2 uses of drugs, and 2 side effect)

~list 4 names of inhaled steroids, adverse effects (candida infections of mouth)

~names of 1st and 2nd line antituberculossi drugs

~discuss MOA of rifampicin and isoniazide

~2 side effects of each drug in 1st line and 2 uses of rifampicin (rifampicin - enzyme inducer)

~list uses of inhaler over WL

~List uses of spacer over MDI WL

~rationale for use of loop dioretics in pulmonary edema

~ratinale for use of thizaides in hypertension

~give rationale for use of spironolactone in congestive heart failure

~describe MOA of loop diuretics, thiazaides, spironolactone

~discuss electrolyte imbalances caused by loop diuretics, thiazides, and spironolactone

~give rationale for combining loop diuretics with spironolactone

~discuss MOA of acetazolamide. list 2 uses.

~give rationale for use of mannitol for CNS injuries

~list 4 uses of montileukast and sodium chormoglycate

~nitrofurantoine and WL

Paper 4

~describe types of insulin and list 4 reason to start insulin to patient

~Describe MOA of biguanides, gliptines, glitazones. list their two ADR of each of them

~list 4 side effects of insulin therapy

~classify insulin analogues

~MOA of thioamides, list 2 uses and 2 side effects

~2 precaustions and 2 contraindications for use of radioactive iodine

~state 4 differences between T3 and T4 in the treatment of thyroid diseases

~describe MOA of combined oral contraceptive pill, side effects, contraindications, 4 uses of
OC pills (PCOD, dyssmenorrhea, hormone therapy, polycyctic ovary)

~2 uses of oestrogen and 2 uses of progesterone

~4 uses of testosterone

~2 ADR of oestrogen, propgesterone, testosterone

~Describe MOA of corticosteroids

~4 uses and 4 ADR of corticosteroids -> important

~classify corticosteroids [time-dependant (short, intermediate, long acting) and ratio of

corticosteroid to minerlocorticoid]

NVS

~MOA of morphine

~4 uses, 4 side effect, 2 contraindications for starting morphine (adbominal pain, raised ICP,
bronchial asthma, glaucoma) --> important

~ list 2 uses of fentanyl

~list names of liver enzyme cyp inhibitors and activators in anticonvulsant drugs (specific)
(most are activators escept sodium something and one more thing)

~list names of non benzodiazepine hypnotics (zedeglaz drugs)

~discuss MOA of piopenthone sodium, ketamine, promapropaphol, benzodiazapines.

~list two important side effects of ketamine (arousal reaction)

~give rationale for liverdopa and cardiodopa in

~classify anti parkinson drugs depending on MOA

~describe MOA of fenytoine, sodium valproate.

~4 side effects of fenytoine.

~4 drugs in which therapeutic drug monitoring (TDM) is done.

~list antidote for benzodiazaipne poisoning (only one drug) (flumazenil)