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Physio

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A pati ent wi th an endocri ne di sorder has l ow potassi um pl asma l evel and


Al dosterone
al kal osi s he i s l i kel y to have excess of

Achal asi a? Lower part of oesphogus ka stenosi s

F i l trati on f racti on i ncreases Oncoti c pressure

F i l trati on of Pl asma protei ns through the gl omerel l a membrane i s prevented


Strong negati ve charge i n proteogl ycans of basement membrane
mai nl y due to
Physio
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I nsul i n decreases i n Ketogenesi s

I ntraocul ar pressure i s mai ntai ned by? Aqueous humor

N eurotransmi tter that i nhi bi ts postsynapti c neurone? Gl yci ne

T hyroxi ne c Uncoupl ers produce heat


Physio
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45 year ol d pati ent f asti ng bl ood gl ucose l evel 135 i ncrease appeti te? D i abetes type 2

60percent semen i s f ormed by? Secreti on of semi nal vesi cl es

7 ketosteroi ds Adrenogeni tal syndrome

A D H acts on whi ch part of ki dney? D i stal convul ated tubul e and col l ecti ng duct
Physio
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A speech di sorder devel ops af ter head i nj ury pati ent started f eel i ng di f f i cul ty i n
utteri ng words. H i s speech became l i mi ted to a f ew words. T here i s most l i kel y Broca's area
damage to?

AD H i nj ecti on f or correcti on Central D I

Acne f ormati on i n gi rl i s brought about by Adrenal androgens

1.D i f f erenti ati on and devel opment of secondary sex organs:


Leydi g cel l s of testes sec teatosterone at 7th to 9th wks of gestati on > ++wol f i an
Acti ons of testosterone duri ng f etal l i f e? duct > i nternal geni tal i a i n mal e
2. H el ps descend of testes f rom abd cavi ty i nto scrotum duri ng l ast 2 to 3 months
of pregs
Physio
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Adrenal medul l a secretes M ore epi nephri ne and l ess N orepi nephri ne

Adrenocorti cal secreti on of al dosterone i s greatl y i ncreased wi th I ncrease potassi um concentrati on i n extracel l ul ar f l ui d

Af ter head i nj ury pati ent devel ops speech def ect there he can understand words
but f eel s di f f i cul ty i n a utteri ng the words speech i s l i mi ted to a f ew words the Broca's area
pati ent i s havi ng damage to

Al dosterone secreti on i s greatl y sti mul ated by? I ncreased potassi um i on concentrati on i n extracel l ul ar f l ui d
Physio
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Al kal i ne secreti ons i n ej acul atory f l ui d by Prostate

Amount of CSF 500ml

An i ncrease i n the permeabi l i ty of cel l s of col l ecti ng tubul e to water i s due to? I ncrease i n producti on of AD H

Brai n can suppress i nput of pai n si gnal s to nervous system by acti vati ng a pai n
Anal gesi a system?
control system cal l ed the anal gesi a system
Physio
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Angul ar accel erati on i s detected by Semi ci rcul ar canal s

Lesi on of hi ppocampus and medi al temporal l obe wi l l cause i nabi l i ty to


Anterograde amnesi a establ i sh new l ong term memory of the type of i nf ormati on that are the basi s of
I ntel l i gence

Anti i nf l ammatory acti on of corti sol i s mai nl y due to Stabi l i z ati on of cel l ul ar l ysosomal membrane

Anti di ureti c hormone secreti on i s sti mul ated by? I ncrease osmol ari ty of body f l ui ds
Physio
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Apraxi a H and ski l l s movement l oss

Aqueous humour has ref racti ve i ndex of 1.34

- destructi on of sensory nerve suppl y


- l oss of tone i n bl adder
Atoni c bl adder i s characteri z ed by
- f i l l i ng of bl adder to to i ts capaci ty
- overf l ow i nconti nence

Babi nski si gn? Bi g toe dorsi f l exi on


Physio
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Beta adrenergi c Cardi o accel erati on

Bi g hands and f eet i n 30 year ol d Acromegal y

Brai n waves i n non RE M sl eep Beta waves

Brai nwave i n a chi l d when sol vi ng probl ems Beta waves


Physio
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Brodmann area of taste 43

Brodmann's area f or taste and gustati on? 3 and 4

CSF secreti on i nvol ves Acti ve transport of sodi um i ons

CSS f ormed i n Choroi d pl exus


Physio
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Resul ts f rom wi despread destructi on of that porti on of the substanti a ni gra the
Cause of Parki nson's di sease (pars compacta) that sends dopami ne secreti ng nerve f i bres to the caudate nucl eus
and putamen

Cause of a toni c bl adder Sensory l oss

Cause of dwarf i sm I nsuf f i ci ent growth hormone produced by the anteri or pi tui tary

Cause of presbyopi a? Protei n denaturati on


Physio
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1. Autoi mmuni ty > Long Acti ng T hyroi d Sti mul ator LAT S, an anti body >bi nds at the
Causes of H yperthyroi di sm? same receptors on thyroi d cel l membrane as T SH > i nc sec of T 3 and T 4.
2. Local i z ed adenoma i n thyroi d gl and > i nc sec of T 3 and T 4.

Cel l s i n the acti on potenti al l ayer of reti na Gangl i on cel l s

Cel l s of ki dney that are chemoreceptors receptors that respond to changes i n


M acul a densa cel l s
sol ute content of a f i l trate?

Contracti on i n both eyes when l i ght i s shown i n one eye


> c a u s e
Consensual l i ght ref l ex
some of the f i bres f rom pretectal nucl eus of one si de cross to the opposi te si de
and end on the opposi te edi nger westphal nucl eus
Physio
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Peri stal si s i n smal l i ntesti ne i s control l ed by f ol l owi ng nervous and hormonal


f actors :
-stretchi ng of duodenal wal l
Control of Propul si ve movements of smal l i ntesti nes?
-gastroenteri c ref l ex
-gastri n, i nsul i n, cck, moti l i n amd serotoni n enhances moti l i ty
-secreti n and gl ucagon i nhi bi ts moti l i ty

Corti sol decreases? Bl ood l ymphocyte count

Couri er i s characteri z ed by danci ng f l i cki ng movements i nvol vi ng hand and f ace i t


Corpus stri atum
i s due to the l esi on of ?

D ef ecati on ref l ex? Parasympatheti c ref l ex


Physio
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D el ta waves i n sl eep? Stage 4

D escendi ng l i mb of l oop of henl e contai ns? F l ui d that becones more concentrated as i t moves down i nto medul l a

D etecti on of hori z ontal accel erati on M acul a of utri cl e

D etermi nati on of the di recti on f rom whi ch the sound comes i s the f uncti on of Audi tory cortex
Physio
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D i f f erence between gl omerul us and other capi l l ari es of body? I ts drai ned by an ef f erent arteri ol e

D i sease caused by i nadequate secreti on of AD H by pi tui tary gl and wi th


D i abetes i nspi dus
symptoms of pol y urea?

-l evodopa/carbi dopa
-L-D eprenyl
D rugs used to treat Parki nson's?
-transpl anted f etal dopami ne cel l s
-by destroyi ng part of the f eedback ci rcui tary

D uri ng devel opment of a hi gh grade f ever wi th chi l l s and ri gors there i s Shi veri ng
Physio
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D uri ng f etal l i f e the devel opment of brai n i s promoted mai nl y by T hyroi d hormones

D utranope Green col our bl i ndness

D ysdi adochoki nesi a I nabi l i ty to perf orm Rapi d al ternati ng movements

E f f ect of AD H on extracel l ul ar osmol ari ty I ncreases


Physio
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-depressi on
E f f ect of H yperthyroi di sm on Brai n? -dec concentrati on
-general l ack of i nterest

-dec heart rate


E f f ect of H yperthyroi di sm on H eart? -i nc/dec bl ood pressure
-dec cardi ac output

-consti pati on
E f f ect of H yperthyroi di sm on I ntesti nes?
-dec GI acti vi ty

-i nc LD L
E f f ect of H yperthyroi di sm on Li ver? -i nc chol estrol
-el evated tri gl yceri des
Physio
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-dec f uncti on
E f f ect of H yperthyroi di sm on ki dneys?
-f l ui d retenti on and edema

-dec f erti l i ty
E f f ect of H yperthyroi di sm on reproducti ve system -menstrual abnormal i ti es
-may harm devel opment of i nf ant

E f f ect of al dosterone on sodi um reabsorpti on I ncreases sodi um reabsorpti on f rom di stal part of renal tubul es

1. M obi l i z es ami no aci ds f rom extra hepati c ti ssues eg muscl es.


2. I nc ami no aci d conc i n bl ood.
E f f ect of corti sol on protei n metabol i sm? 3. I nc transport of ami no aci ds i nto hepati c cel l s f or:
-i nc protei n synthesi s
-i nc gl uconeogenesi s
Physio
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E f f ect of dopami ne on prol acti n secreti on D ecreases prol acti n secreti on

Au t o no mi c c o nt ro l : i nc GI T acti vi ty
-crani al porti on by vagus nerve
-sacral porti on by 2nd, 3rd and 4th pel vi c spl anchni c nerve
-postgangl i oni c neurons are l ocated i n myenteri c and submucosal pl exus.
E f f ect of parasympatheti c sti mul ati on on GI T ?
F u nc t i o ns :
>i nc peri stal si s and tone
>rel axes sphi ncters
>i nc di gesti ve secreti ons

E f f ect of parasympatheti c sti mul ati on on pupi l Constructi on of pupi l

-I nhi bi ts GI T acti vi ty
-f i bres ori gi nate i n spi nal cord between segments t5 to L2
-some f i bres enter sympatheti c chai ns and then pass to cel i ac gangl i on a myenteri c
gangl i on
M ost of the post gangl i oni c neurones are i n thi s gangl i on
E f f ect of sympatheti c sti mul ati on on gi t - i nnervates al l the GI T securi ty.
-secrete epi nephri ne and norepi nephri ne
F u nc t i o ns
> decrease peri stal si s and tone
> contracts sphi ncters
>decrease di gesti ve secreti on
Physio
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I t causes motor aphasi a. T he person i s capabl e of deci di ng what he want to say


E f f ects of l esi on i n Broca's area
but cannot make the vocal system emi t the words

Pancreas secretes 2 hormones:


1. I ns u l i n (beta cel l s) : promotes gl ucose entry i n many cel l s and i n thi s way
E ndocri ne f uncti on of pancreas? promotes carb metabol i sm
2. G l u c a g o n (al pha cel l s) : i nc synthesi s and rel ease of gl ucose f rom l i ver i nto
body f l ui ds

E ngorgement i n erecti on occurs i n Corpora cavernosa

Prol acti n
Oxytoci n
E numerate hormones that take part i n l actati on
estrogen
progesterone
Physio
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E pi thel i um f ormi ng uri nary bl adder? T ransi ti onal epi thel i um

E xcreti on of di l ute uri ne requi res? I mpermeabi l i ty of col l ecti ng tubul e to water

> i t i s associ ated wi th consci ousness or at l east awareness and i s dependent on


the hi ppocampus and other parts of the medi al temporal l obes of brai n f or i ts
E xpl i ci t or D ecl arati ve M emory? retenti on
>events and F acts ,memory of surroundi ngs, ti me rel ati onshi p, cause meani ng of
experi ence

E ye f ocused i n f ront of reti na? M yopi a


Physio
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F actor i ncreasi ng gastri c moti l i ty M oti l i n

F ast conducti ng pai n f i bre A Al pha f i bre

F ast pai n i s transmi tted by whi ch tract? D orsal col umn

-buf f al o torso
-moon f ace
-mascul i ni z i ng ef f ects
- i nc bl ood gl ucose l evel
-i nc bl ood corti sol l evel
-i nc uri nary sec of 17 hydroxysteroi ds
-verti go
-acne
F eatures of Cushi ngs Syndrome?
-bl urry vi si on
-f emal e bal di ng
-water retenti on
-menstrual abnormal i ti es
-purpl e stri ae
-thi n ski n and brui si ng
-poor wound heal i ng
-hi rsuti sm
-severe depressi on
-cogni ti ve di f f i cul ti es
Physio
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> l oss of sensory nerve f i bres


> di stended atoni c bl adder wal l
F eatures of atoni c bl adder?
> overf l ow dri bbl i ng
> tabes dorsal i s

1.D ysmetri a and ataxi a


2. past poi nti ng
3. D ysdi adochoki nesi a
4. D ysarthi a
F eatures of cerebel l ar di sease?
5. I ntenti on tumor
6. Cerebel l ar nystagmus
7. Astheni a
8. H ypotoni a

> upsi de down representati on of body parts


> i ni ti ate vol untary movements
F eatures of pri mary motor area?
> contai ns a granul ar type of cerebral cortex
> brodmann's area 4 i s present i n i t

> 30% of i ts f i bres ari se f rom pri mary motor area


> 30% of i ts f i bres ari se f rom pre motor and suppl ementary motor area
F eatures of pyrami dal tract?
> i t control s vol untary f i ne ski l l s movements speci al l y of di stal parts of l i mb
> most of i ts f i bres crossover to f orm medul l ary motor decussati on
Physio
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F etal Ki dneys don't have to work very hard because? Pl acenta al l ows the mothers uri nary system to cl ear the waste f rom f etal bl ood

F i bres of D CM L system decussate i n M edul l a obl ongata

F i l trati on f racti on? Rati on of gl omerul ar f i l trate rate GF R to renal pl asma f l ow RPF

1. Gl omerul ar endothel i um
F i l trati on membrane i ncl udes? 2. Podocytes
3. Basement membrane
Physio
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F i nd touch and two poi nt di scri mi nati on i s transmi tted by D cml system

E R and gol gi apparatus of thyroi d f ol l i cul ar cel l s f orm and secrete a gl ycoprotei n
F ormati on and secreti on of thyrogl obul i n on synthesi s of thyroi d hormones? cal l ed thyrogl obul i n i nto f ol l i cl es, contai ni ng 70 tyrosi ne ami no aci d resi dues.
T 3 and T 4 are f ormed as parr of thyrogl obul i n

F ovea of eye H i ghest vi sual acui ty

- mai ntai ns h o me o s t a s i s by control l ong tj e composi ti on, vol ume and pressure of
bl ood
F uncti on of Uri nary Sysyem -regul ates b l o o d g l u c o s e l e ve l s
-produces h o rmo ne s
-mai ntai ns bl ood o s mo l a ri t y
Physio
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F uncti on of attenuati on ref l ex? Protects the i nner ear f rom the damage by very l oud sounds

F uncti on of j uxtagl omerul ar apparatus? Regul ate BP and rate of bl ood f i l trati on by ki dneys

F uncti on of l oop of henl e? F orms l arge vol ume of very di l ute uri ne a smal l vol ume of very concentrated uri ne

F uncti on of muscl es spi ndl es? Regul ate l ength of


Physio
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F uncti on of progesterone on breasts Al veol o l obul ar devel opment

M ai ntai ns uteri ne l i ni ng
F uncti on of the pl acental estrogen
Sti mul ates mammary gl ands

T hey of f er
1.nutri ti on
2.support
3.spermatogenesi s
F uncti ons of sertol i cel l s
4.spermi ogenesi s
5.mul l eri an i nhi bi tory f actor
6.estradi ol
7.i nhi bi n

1. Acts as the mai n sensory rel ay centre


2. H as a rol e i n the control of motor acti vi ty
F uncti ons of thal amus?
3. Past of reti cul ar acti vati ng system
4. Part of l i mbi c system
Physio
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F unctoon of angi otensi n l l Constri ct areteri ol es and i nc bl ood pressure

Gastri n i s rel eased f rom? Pyl ori c gl and of stomach

Gl omerul ar f i l trati on rate i s i ncreased by H ypotensi on

Gl omerul ar f i l trati on rate i s i ncreased wi th decreased? Pl asma col l oi d osmoti c pressure


Physio
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Gl uconeogenesi s i s promoted by Gl ucagon

Gl ucose reabsorpti on occurs at? Proxi mal tubul e

Gl ucose reabsorpti on occurs at? Proxi mal tubul e

Growth hormone decreases Protei n catabol i sm


Physio
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Growth retarded mental i ty normal Pi tui tary dwarf

T ri l ayered:
M ucosa
H i stol ogy of ureters?
M uscul ari s
Adventi ti a

H ormone decreased i n menopause Oestrogen

H ormone i ncreased i n f i rst tri mester? H cG


Physio
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H ormone produci ng growth of al veol i l obul es and secretory changes i n the breast
Progesterone
is

H ormone rel eased f rom z ona gl omerul osa Al dosterone

H ormone rel eased f rom z ona gl omerul osa? Al dosterone

H ormone responsi bl e f or f acul tati ve water reabsorpti on? AD H


Physio
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- dopami ne
- epi nephri ne
H ormones deri ved f rom tyrosi ne
- norepi nephri ne
- thyroxi n and T 3

1.testosterone
2.F SH
H ormones whi ch control sperm f ormati on? 3.LH
4.GH
5.estradi ol

H ow does al cohol act as di ureti c? I nhi bi ts rel ease of AD H

I ncreased H + I on concentrati on i n metabol i c aci dosi s > sti mul ates respi ratory
H ow i s metabol i c aci dosi s compensated centre i n medul l a > i ncrease rate of Pul monary venti l ati on > excess CO2bl own of f
>H + i on conc dec to normal
Physio
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1. I odi ne trappi ng(i odi de pump)


2. F ormati on and aecreti on of thyrogl obul i n
H ow thyroi d hormones are synthesi z ed?
3. Oxi dati on of i odi de
4. I odi nati on of tyrosi ne (organi f i cati on of tyrosi ne)

H ypercal cemi a and hypophosphatemi a Pth

- addi son's di sease


- di arrhoea
H ypernatremi a i s present i n
- overdose of di ureti cs
- vomi ti ng

H yperopi a cause Weak l ens system


Physio
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I f T m f or a parti cul ar ami no aci d i s 120 mi l l i gram per 100ml and the
concentrati on of that ami no aci d i n the bl ood i s 230 mi l l i gram per hundred ml ,the Wi l l appear i n uri ne
ami no aci d?

I f a man dri nks 3 gl asses of water there i s i nhi bi ti on of secreti on of A d h

I f ovum i s not f erti l i z ed, menstruati on occurs. Why? Reducti on i n estrogens and progesterone

I f the cl earance val ue of gl ucose i s z ero what does i t mean? N ormal l y al l gl ucose i s reabsorbed
Physio
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I mpedance M atchi ng by whi chbone F ootpl ate of stapes

I mpedance M atchi ng? F ootpl ate of stapes

D oes not i nvol ve awareness and i ts retenti on does not usual l y i nvol ve processi ng i n
the hi ppocampus
I mpl i ci t or non decl arati ve memory? >such as al l the ski l l s devel oped f or hi tti ng a tenni s bal l i ncl udi ng automati c
memory to si ght the bal l and cal cul ate the rel ati onshi p and speed of the bal l to
the racket

I mportant hormone regul ator's of el ectrol yte reabsorpti on and secreti on? Angi otensi n l l and Al dosterone
Physio
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I n I mpedance M atchi ng rol e of stapes F orce of movement of stapes i s i ncreased

I n a pati ent havi ng ri ght si ded hemi secti on of spi nal cord on the contral ateral
Pai n
si de bel ow the hemi secti on there i s l oss of ?

I n ascendi ng Li mb of l oop of henl e? T he thi ck segment moves i ons out i nto i ntersti ti al spaces f or reabsorpti on

I n body F l ui ds phosphate buf f er i s qual i tati vel y more powerf ul than bi carbonate
pKa val ue 6.8
buf f er because i t has
Physio
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I n chi l dren when eyes are f ocused on an obj ect the ref racti ve power of l ens i s
14 di opters
i ncreased by

I n conducti ve deaf ness ef f ect on the af f ected ear Webberz test i s l ateral i z ed

I n metabol i c al kal osi s there i s i ncreased Pl asma bi carbonate concentrati on

I n metabol i c al kal osi s there i s i ncreased? Pl asma bi carbonate concentrati on


Physio
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I n nerve deaf ness of ri ght ear? Weber's test i s l ateral i z ed on the l ef t si de

I n pati ents of thyrotoxi cosi s or Graves di sease there i s decrease pl asma l evel of ? T SH

I n pregnancy there i s i nhi bi ti on of secreti on of ? Anteri or pi tui tary gonadotropi ns

I n sensory aphasi a there i s damage to Werni cke's area


Physio
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I n the bl ood gl ucocorti coi d decrease the number of Lymphocytes

I nabi l i ty to see the other si de? Opti c tract compressi on

I nf arct of i nternal capsul e resul ts i n Contral ateral spasti c chroni c paral ysi s

I nsul i n i ncreases Protei n synthesi s


Physio
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I ntracel l ul ar water amount 28 l i tre water

Serum f ree T 3 and t4 l evel s > hi gh


I nvesti gati ons f or H yperthyroi di sm?
T SH l evel s > l ow

Acti ve transport of i odi de f rom E CF i nto thyroi d f ol l i cul ar cel l s and then i nto
I odi ne trappi ng i n synthesi s of thyroi d hormones?
f ol l i cl es

Regul ati ng rate of f i l trate f ormati on


Juxtagl omerul ar apparatus i s responsi bl e f or?
Control l i ng systemati c bl ood pressure
Physio
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Ketoaci dosi s i s f ound i n? Uncontrol l ed di abetes mel l i tus

Ketone bodi es are f ormed i n excess when there i s def i ci ency of I nsul i n

Ki dneys devel op f rom? Urogeni tal ri dges

Labour i s brought by? F etal ACT H


Physio
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Lef t homonymous hemi anopi a i s due to Ri ght opti c tract

Lesi on of ri ght opti c tract Lef t homonymous hemi anopi a

Levi l orai n dwarf i sm i s caused by l ack of ? Somatomedi an c

T he pri mary motor cortex l i es i n the f i rst conversati on of the f rontal l obes i nteri or
to the central sul cus. i t begi ns l i teral l y i n the syl vi an f i ssure, spreads repeatedl y
Locati on of pri mary motor cortex
to the upper most porti on of brai n, and then takes deep i nto the l ongi tudi nal
f i ssure
Physio
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Loss of recent memory occurs when there i s l esi on of H i ppocampus

M acul a densa cel l s respond to? Changes i n sol ute content of f i l trate

M acul a densa i s part of ? 1st part of di stal tubul e

M agnet ref l ex Supporti ng ref l ex


Physio
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M ai n f orce of f i l trati on Gl omerul ar hydrostati c pressure

M axi mum producti on of sperm? Adol escence

M echani sm of water re absorpti on by renal tubul es i s? Osmosi s

M essenger system f or ol f actory messenger Camp


Physio
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M i d col l i cul ar secti on of mi dbrai n D ecerberate ri gi di ty

M i ni mum separabl e di stance f or two poi nts tacti l e di scri mi nati on i s on? T i ps of f i ngers

M i xi ng M ovement i n smal l i ntesti ne Segmentati on

M ost el ectrol yte re absorpti on by renal tubul es i s? H ormonal l y control l ed i n di stal tubul e segments
Physio
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M ost of ref racti on i n eye occurs at Anteri or surf ace of cornea

M ost of water reabsorpti on through renal tubul es i s by Osmosi s

M ovements i n i ntesti ne Segmentati on and constructi on

M ovements i n ureters? Ureters are capabl e of peri stal si s l i ke GI T


Physio
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M uscl e l ength organ M uscl es spi ndl e

N atural compounds f or measuri ng GF R i n the body Creati ni ne

N ormal pl asma cal ci um Level 9.8 to 11.5mg/dl

N ot a method by whi ch the cel l s of renal tubul es can rai se bl ood PH ? By secreti ng sodi um i ons
Physio
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N ot i n cerebel l ar l esi on Sensory l oss

Obl i gatory uri ne? 500ml

Li ver
I ntesti nes
Reproducti ve
Organs af f ected by hyperthyroi di sm?
Brai n
H eart
Ki dneys

Removal of el ectron. I odi de I - i s oxi di z ed to l 2 i n thyroi d f ol l i cl es. T hi s process


Oxi dati on of I odi de i n synthesi s of thyroi d hormones?
i s accel erated by peroxi dase and hydrogen peroxi de.
Physio
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PT H f uncti on on bone cel l s Osteocl asts acti vi ty

Pai n rel easi ng **** E nkaphl i n

Pal pi tati ons,


l oss of wei ght despi te i nc appeti te
I ntol erance to heat
Pul se rate 110/mi n H yperthyroi di sm (toxi c goi ter, thyrotoxi cosi s, graves)
Promi nent eyes
Swel l i ng on ant si de of neck
D i agnosi s?

Pancreati c enz yme Chol ecystoki ni n


Physio
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Parathyroi d hormone decreases E xcreti on of cal ci um i n uri ne

Parathyroi d hormone i ncreases? Renal tubul ar reabsorpti on of cal ci um

Pari etal cel l s secrete? H CL and i ntri nsi c f actor

Parki nson's di sease i s due to i mbal ance of neurotransmi tters i n basal gangl i a
Acetyl chol i ne and dopami ne
these neurotransmi tters are
Physio
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Part damaged i n parki nsoni sm Substanti a ni gra

- granul ar cel l s
Parts of j uxtagl omerul ar apparatus? - macul a densa
- mesangi al cel l s

Parturati on i s brought about by? Oxytoci n and prostagl andi ns?

-H ypertensi on causes general i z ed edema due to sal t and water retenti on.
-D ec i n f uncti on of neurons >I nc i n urea and other protei n ni trogens such as
creati ni ne whi ch are the end products of protei n metabol i sm must be remi ved f rom
body, causes uremi a > symptoms of uremi a: nausea, vomi ti ng, mental deteri orati on,
Pathophysi ol ogy of chroni c renal f ai l ure? conf usi on
-Aci d accumul ati on i n body f l ui ds> budf eri ng power used up > bl ood pH f al l s
and pati ent wi l l comatose> death i f pH f al l s bel ow 6.8
(body f l ui ds can normal l y buf f er 500 to 1000 mi l l i mol es of aci d and phosphate
compounds can buf f er addi ti onal f ew thousand mi l l omol es of aci d)
Physio
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Pathway of l i ght ref l ex does not i nvol ve Vi sual cortex

Pati ent wi th cerebel l ar di sease i s not l i kel y to have? Stati c tremors

Pati ent wi th ri ght homonymous hemi anopi a i s l i kel y to have a l esi on i n? Lef t opti c tract

Percentage of f i l tered sodi um reabsorbed i n the proxi mal tubul e i s about? 65percent
Physio
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Permeabi l i ty of Urea i n i nner medul l ary col l ecti ng duct i s i ncreased by A d h

A) sti mul ates gl uconeogenesi s i n l i ver by metavl i z i ng ami no aci ds i n extrahepati c


ti ssues(muscl es) and i nc the enz ymes of gl uconeogenesi s.
Physi ol ogi cal acti on of corti sol on carb metabol i sm? B) dec gl ucose uti l i z ati on by cel l s by dec the oxi dati on of N AD H 2 requi red f or
gl ycol ysi s and bt dec the gl ucose transport i nto cel l s.
C) I mc bl ood gl ucose l evel by i nc gl uconeogenesi s and dec gl ucose uti l i z ati on.

Pi tch percepti on of sound havi ng f requency l ess than 2000 words i n the organ of
Vol l eys theory
corti i s due to

Pl asma bi carbonate i ncreases i n M etabol i c al kal osi s


Physio
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Post gangl i oni c sympatheti c chol i nergi c nerve f i bres suppl y Sweat gl ands

Post ovul atory phase of menstrual cycl e by whi ch hormone F SH

Post ovul atory phase of menstrual cycl e? F SH

Pregnancy on menstrual cycl e hormones H CG


Physio
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Premature ej acul ati on Sympatheti c l oss

Prol acti n f rom the anteri or pi tui tary causes? M i l k secreti on i n breast

- beta waves i n E E G
- acti ve dreami ng
RE M sl eep i s characteri z ed by
- D el ta waves i n E E G
- rapi d eye movement

> beta waves i n E E G


> dreams whi ch can be recal l ed
RE M sl eep i s characteri z ed by?
> i rregul ar respi rati on
> Rapi d movements of the eye
Physio
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Reabsorpti on of hi gh l evel s of gl ucose and ami no aci ds i nf i l trate i s


Secondary acti ve transport
accompl i shed by?

Reabsorpti on of sodi um and chl ori de i n di stal tubul es and col l ecti ng duct i s
Al dosterone
i ncreased by

Reabsorpti on of water i s? H ormonal control

Reason f or dec of ki dney f uncti on i n ol der adul ts? Ki dney atrophy


Physio
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- they l ack carri ers


Reasons why substances are ei ther not reabsorbed or are i n compl etel y reabsorbed
- they are not l i qui d sol ubl e
f rom the nephron?
- they are too l arge to pass through the f enestrati ons

Receptors f or thyroi d hormones are l ocated i n DNA

Receptors whi ch undergo sl ow adaptati on or are H ai r f ol l i cl e receptors

Ref racti ve power i n chi l d 14 di opter


Physio
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A) CRF a pepti de sec by post medi al basal hypothal amus > ACT H a pepti de sec
by ant pi tui tary gl and > corti sol sec by adrenal cortex.
B) D i f f erent stresses eg trauma i nf ecti on operati on > corti sol sec by adrenal
Regul ati on of Corti sol ? cortex.
C) Corti sol > negati ve f eedback i nhi bi ton of ACT H CRF .
D ) Ci rcadi an rhythm sec rates of CRF ACT H and corti sol : hi gh i n earl y morni ng,
l ow i n l ate eveni ng

Rel ease of human chori oni c gonadotropi n f rom pl acenta sti mul ates Leydi g cel l s of mal e testes

Renal bl ood f l ow? 1100ml /mi n

Bowman's capsul e
Renal corpuscl e i s made up of ?
Gl omerul us
Physio
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Reni n i s secreted by? JG cel l s

Renni n i s rel eased f rom JG cel l s

Reti nal cel l s i nvol ved i n l ateral i nhi bi ti on are H ori z ontal cel l s

Retrograde amnesi a I nabi l i ty to recal l memori es f rom the past


Physio
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Rol e of aqueous humour M ai ntai ns i ntraocul ar pressure behi nd l ens

Rol e of f atty ti ssue surroundi ng the ki dney? Stabi l i z es the posi ti on of ki dneys by hol di ng them i n normal posi ti on

Secreti on of growth hormone i s i ncreased by E xerci se

Semi ci rcul ar canal s can detect? Vel oci ty of angul ar accel erati on
Physio
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- crude touch
- pi n
Sensati ons carri ed by spi nothal ami c tract
- temperature
- ti ckl e

Sensory Associ ati on area l esi on ef f ect I nabi l i ty to recogni se opposi te si de of body

Sensory receptors whi ch respond to rotati on of head are present i n Cri sta ampul l ari s

Sensory receptors whi ch undergoes sl ow adaptati on? F ree nerve endi ngs
Physio
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Sequence f rom f ormati on of uri ne drop to i ts el i mi nati on f rom the body? N ephron > col l ecti ng duct > mi nor cal yx >maj or cal yx > ureter > urethra

Serum f sh l evel i ncreases when there i s a l ow l evel of Oestrogen

Si te of spermatogenesi s Semi ni f erous tubul es

Snel l en chart i s f o r Vi sual acui ty


Physio
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Sodi um bal ance i s regul ated mai nl y by the control of amounts of sodi um E xcreted i n uri ne

Sodi um concentrati on and osmol ari ty of extracel l ul ar f l ui d i s control l ed mai nl y


AD H
by?

Sodi um i s reabsorbed f rom the baso l ateral surf ace of Renal tubul ar epi thel i al
Sodi um hydrogen exchange
cel l s by

Spasti c paral ysi s? UM N


Physio
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Speci f i c Gravi ty or densi ty of uri ne? 1.001 to 1.035

Speech area? Brocas area

Stapedi us and tensor tympani rol e Attenuati on ref l ex

Stomach emptyi ng? CCK


Physio
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T emperature i s i ncreased by the hormone? Progesterone

T estosterone decreases Growth of hai r on scal p

T hal amus i s i nvol ved i n the control of Autonomi c nervous system

T he bi tter taste i s maxi mal l y percei ved on Back of tongue


Physio
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T he chi ef source pushi ng water and sol utes out of bl ood across f i l trati on
Gl omerul ar hydrostati c pressure(gl omerul ar bl ood pressure)
membrane i s?

T he ef f ect of sympatheti c sti mul ati on medi ated through beta-adrenergi c


Cardi oaccel erati on
receptors i s?

T he endogenous substance i n the human body whi ch can be used to measure


Creati ni ne
gl omerul ar f i l trati on rate by renal cl earance i s?

T he f actors f avouri ng f i l trate f ormati on at gl omerul us? Gl omerul ar hydrostati c pressure


Physio
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T he f ood contai ni ng and gl utamate gi ve the taste? Umami

T he greatest amount of H + secreted by proxi mal tubul e i s associ ated wi th E xcreti on of potassi um i on

T he growth hormone acti on on f atty aci ds I ncreases uti l i sati on of f atty aci ds f or energy

T he hormone acti ng on the target cel l s through the acti vati on of phosphol i pase C
Gonadotropi n rel easi ng hormone
i s?
Physio
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T he ki dneys are sti mul ated to produce Reni n by? A dec i n bl ood pressure

T he l i ght rays comi ng f rom di stant obj ects are f ocused i n f ront of the Reti na i n? M yopi a

- countercurrent mul ti pl i er mechani sm


- countercurrent exchanger mechani sm
T he mechani sm f or excreti on of concentrated uri ne i nvol ves?
- hyperosmol ari ty of renal medul l ary i ntersti ti um
- presence of anti di ureti c hormone

T he mechani sm that establ i shes the medul l ary osmoti c gradi ent depends mostl y
Loop of henl e
on permeabi l i ty properti es of ?
Physio
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T he pKa of aci d i n phosphate buf f er i s? 6.8

T he pari etal l ayer of gl omerul ar capsul e? Si mpl e squamous epi thel i um

T he part of renal tubul es i mpermeabl e to water i s T hi ck ascendi ng Li mb of l oop of henl e

T he permeabi l i ty f or urea i n i nner medul l ary col l ecti ng duct i s i ncreased by A D H


Physio
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- pri mary motor area


- premoter area
T he pyrami dal tract contai n f i bres f rom
- somati c sensory areas
- vi sual areas

T he ref l ex havi ng pol ysynapti c ref l ex arc i s I nverse stretch ref l ex

T he reti nal cel l s whi ch generate acti on potenti al al ong the opti c nerve f i bres are? Gangl i on

T he secretory changes i n uteri ne endometri um and i nhi bi ti on of uteri ne contracti on


Progesterone
i s the f uncti on of ?
Physio
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T he total ref racti ve power of eye i n di opters i s 59

T otal body water can be measured by usi ng Radi oacti ve? Water (tri ti um)

T otal quanti ty of gl omerul ar f i l trate f ormed per day i s 180 l i tres

T ubul ar reabsorpti on by acti ve mechani sm usual l y i nvol ves? M ovement agai nst an el ectri cal and or chemi cal gradi ent
Physio
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T wo poi nt di scri mi nati on i s del i vered by whi ch tract? D orsal col umn

T wo poi nt di scri mi nati on i s transmi tted by D orsal col umn sensati on

T ype of edema that devel ops i n hyperthyroi d pati ents? M yxedema

T ype of pai n transmi tted by dorsal col umn tract F ast pai n
Physio
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1. E xcretory
2. Regul atory
T ypea of f uncti ons of ki dney?
3. Syntheti c
4. E ndocri ne

N ucl ear bag f i bres


T ypes of i ntraf usal f i bres
nucl ear chai n f i bres

D ecl arati ve or expl i ci t


T ypes of memory?
N on decl arati ve or i mpl i ci t

Unmyel i nated f i bres T ype c


Physio
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Uri nary excreti on of vanl l yl mandel i c aci d i ncreases when there i s i ncrease
Catechol ami nes
secreti on of

Pel vi s of ki dney
To
Ureter
Uri ne passes through? To
Bl adder
To
Urethra

Val ue of GF R? 125ml /mi n or 180l i tre/day

Water f i l ter i nto renal tubul es i s maxi mal l y reabsorbed i n Proxi mal tubul e
Physio
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Water reabsorpti on does not occur i n? Ascendi ng l oop of henl e

Werni cke's area? T emporal l obe

1. I nc proteol ysi s of thyrogl obul i n that has al ready been stored i n the f ol l i cl es,
resul tong i n rel eaae of thyroi d hormones i n ci rcul ati ng bl ood and di mi ni shment of
the f ol l i cul ar substance i tsel f .
2. I nc acti vi ty of i odi de pump whi ch onc rate of i odi ne trappi ng i n gl andul ar
cel l s,sometomes i nc the rati o of i ntracel l ul ar to extracel l ul ar I conc i n gl andul ar
Wf f ect of T SH thyroi d gl and? substance to as much aa 8x normal .
3. I nc i odi nati on of tyrosi ne to f orm thyroi d hormones.
4. I nc si z e and sec acti vi ty of thyroi d cel l s.
5. I nc i n no of thyroi d cel l s and change f rom cuboi dal to col i mnar cel l s and much
i nf ol di ngs of thyroi d epi thel i em i nto f ol l i cl es.
H ence T SH i nc al l known sec f uncti ons of thyroi d gl andul ar cel l s

What acts as a tri gger f or i ni ti ati on of M i cturi ti on? Stretchi ng of bl adder wal l
Physio
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1.I ncreased pl asma col l oi d osmoti c pressure


2.I ncrease bowman's capsul e pressure
What are the decreasi ng f actors of GF R?
3.af f erent arteri ol ar
4. Sympathati c si mul ati on (because of af f erent arteri ol ar constri cti on)

1.Acts as a shock absorber


2.acts as a cushi on between sof t and del i cate brai n and ri gi d crani um
3.acts as a f l ui d buf f er
What are the f uncti ons of CSF
4.acts as a reservoi r to regul ate contents of crani um
5.medi um f or nutri ti onal exchange 6.removes metabol i tes
7.transports medi ci ne

T he are three systems f or regul ati on of aci d base bal ance:


What are the l i nes of D ef ence agai nst changes i n H posi ti ve I on concentrati on of -Aci d base buf f er system
body f l ui ds -Respi ratory system
-Renal system

What does pari etal cel l s secrete H CL and i ntri nsi c f actor
Physio
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T he short term memory, i f acti vated repeatedl y, wi l l i ni ti ate chemi cal physi cal
and Anatomi cal changes i n the synapses that are responsi bl e f or the l ong term type
of memory.
What i s consol i dati on of memory
>thi s process requi res 5 to 10 mi ns f or mi ni mal consol i dati on and 1 hr or more f or
stri ng consol i dati on.
> rehearsal enhances the transf erence of short term memory i nto l ong term memory

What i s the sal t l evel moni tori ng part of nephron? M acul a densa

What woul d happen i f capsul ar hydrostati c pressure were i ncreased was normal ? N et f i l trati on woul d decrease

When a baby cycl es mothers breast the hormone i nvol ved i n mi l k ej ecti on i s Oxytoci n
Physio
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Podocyte
Whi ch **** i s associ ated wi th the Renal Corpuscl e? F enestrated capi l l ary
E f f erent arteri ol e

Whi ch artery l i es on the boundary between cortex and medul l a of ki dney? Arcuate artery

Whi ch hormone causes stretch of cervi x Oxytoci n

Whi ch hormone i ncreases 2 days bef ore ovul ati on LH


Physio
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Whi ch hormone i ncreases extracel l ul ar osmol ari ty? AD H

- renal auto regul ati on


Whi ch i s a gl omerul ar f i l trati on rate control method? - neuronal regul ati on
- hormonal regul ati on

Whi ch i s not absorbed by proxi mal convul ated tubul e? Creati ni ne

Whi ch l esi on causes compl ete bl i ndness i n eye? Opti c nerve


Physio
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P i g me nt e d l a ye r as vi t A i s stored i n thi s l ayer.


Whi chl ayer of reti na becomes i mpai red i n nyctal opi a?
L a ye r o f ro d s as vi t A i s i nvol ved i n f ormati on of reti nal and rhodopsi n

>Posteri or spi nocerebel l ar f i bres recei ve muscl e j oi nt i nf ormati on f rom the muscl e
spi ndl es, tendon organs and j oi nt receptors of the trunk and l ower l i mbs.
-T hi s i nf ormati on regardi ng tensi on of muscl es and j oi nts i s used by the
cerebel l um i n the mai ntenance of posture
Why does a person wi th cerebel l ar di sease has di f f i cul ty i n mai ntai ni ng bal ance? >anteri or spi nocerebel l ar tract provi ded the same i nf ormati on f rom upper and l ower
Li mbs
>Cuneocerebel l ar tract provi de i nf ormati on of muscl e j oi nt
>i n cerebel l ar l esi on, the cerebel l um cannot comprehend thi s i nf ormati on and
resul ts i n l oss of bal ance

Wri thi ng i s caused by a l esi on i n Gl obus pal l i dus

i n metabol i c aci dosi s there i s decreased Pl asma bi carbonate concentrati on


Physio
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pl asma cl earance of phosphate i s brought about by PT H

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