Franzi Alyanna A.

Mugar BSN 4F - 09/16/22

DRUG STUDY

Name of Drug Dosage/Frequency/Timing/Route Mechanism of Indication Contraindication Adverse Effect Nursing

Action Responsibilities
Generic: Dosage: Interferes with cell- Moderate to severe Hypersensitivity to CNS: Lethargy, Assess:
Piperacillin/tazobactam 45mg wall replication of infections: penicillins; hallucinations, -Infections in
Frequency: susceptible piperacillin-resistant, neonates; anxiety, depression, temperature,
Brand: Q6H organisms; β-lactamase– carbapenem twitching, insomnia, stools, urine,
Dxpita Timing: tazobactam is a β- producing strains allergy headache, fever, sputum, wounds
12am, 12pm, 6am, 6pm lactamase inhibitor causing infections in dizziness, seizures, -I&O ratio; report
Classification: Route: IVTT that protects respiratory, skin, vertigo hematuria, oliguria
Func. class.: Antiinfective, broad piperacillin from urinary tract, bone, -CDAD: diarrhea,
spectrum enzymatic gonorrhea, CV: Cardiac toxicity, bloody stools,
Chem. class.: Extended-spectrum degradation pneumonia. edema fever, abdominal
penicillin, β-lactamase inhibitor cramps; bowel
GI: Nausea, vomiting, pattern
diarrhea; abdominal -Skin eruptions after
pain, constipation, administration
pancreatitis -Respiratory status:
rate, character,
GU: Oliguria,
wheezing,
proteinuria,
tightness in chest
hematuria, vaginitis,
-Anaphylaxis:
renal failure HEMA:
 wheezing,
Anemia, increased laryngeal edema,
bleeding time, bone rash, itching;
marrow depression, discontinue
product, have
INTEG: Rash, pruritus, emergency
exfoliative dermatitis equipment nearby

SYST: Serum sickness,

anaphylaxis, Stevens-
Johnson syndrome
Generic: Dosage: Inhibits Pulmonary edema; Hypersensitivity to CNS: Headache, Assess:
Furosemide 40mg reabsorption of edema with HF, Anuria fatigue, weakness, -MIO
Frequency: sodium and chloride hepatic disease, vertigo, paresthesias -Hypertension: B/P
Brand: BID at proximal and nephrotic syndrome, CV: Orthostatic -Hypokalemia:
Lasix Timing: distal tubule and in ascites, hypertension hypotension, chest postural
8am, 6pm the loop of Henle pain, ECG changes, hypotension,
Classification: Route: circulatory collapse fatigue,
Func. class.: Loop diuretic IVTT EENT: Loss of hearing, tachycardia, leg
Chem. class.: ear pain, tinnitus, cramps,
Sulfonamide derivative blurred vision -Rashes, temperature
ENDO: Hyperglycemia elevation daily
GI: Nausea, diarrhea, -Confusion, especially
dry mouth, vomiting, in geriatric
anorexia, cramps, oral, patients;
gastric irritations, -Hearing, including
 pancreatitis tinnitus and
GU: Polyuria, renal hearing loss,
failure, glycosuria, when giving high
bladder spasms doses for extended
HEMA: periods or rapid
Thrombocytopenia, infusion
agranulocytosis, -Rate, depth, rhythm
leukopenia, of respiration
neutropenia, anemia -Glucose in urine
SYST: Toxic epidermal -Serious rash: monitor
necrolysis, erythema , for skin rash often;
Stevens-Johnson Stevens-Johnson
syndrome syndrome, toxic
necrolysis,
erythema
multiform may
occur and are life
threatening
Generic: Dosage: Binds to Prevention of DVT Hypersensitivity to CNS: Fever, confusion, Assess:
Enoxaparin 0.4 cc antithrombin III (inpatient or this product, dizziness, headache -Bleeding: gums,
Frequency: inactivating factors outpatient), PE heparin, pork; GI: Nausea, vomiting, petechiae,
Brand: BID Xa/IIa, thereby (inpatient) in hip and active major constipation HEMA: ecchymosis, black
Clexane Timing: resulting in a higher knee replacement, bleeding, Hemorrhage from any tarry stools,
8am, 6pm ratio of anti–factor abdominal surgery at hemophilia, site, hematuria; notify
Classification: Route: Xa to IIa. risk for thrombosis; leukemia with INTEG: Ecchymosis, inj prescriber
Func. class.: SC unstable angina, bleeding, site hematoma, - Anaphylaxis,
Anticoagulant, acute MI, coronary thrombocytopenic alopecia, rash META: angioedema:
antithrombotic Chem. artery thrombosis. purpura, heparin- Hyperkalemia in renal monitor for rash,
class.: Low-molecular- induced failure swelling of face,
weight heparin (LMWH) thrombocytopenia MS: Osteoporosis lips, tongue,
SYST: Edema, dyspnea; stop
peripheral edema, product, initiate
angioedema, emergency
anaphylaxis procedures
-Neurologic status:
those with epidural
catheters are at
greater chance for
impairments
-Injection-site
reactions:
inflammation,
redness,
hematomas
Generic: Dosage: Blocks pain impulses Mild to moderate pain Hypersensitivity to CNS: Confusion, Asses:
Aspirin 80mg by blocking COX-1 or fever, including salicylates, seizures, headache, -Pain: character,
Frequency: in CNS, reduces rheumatoid arthritis tartrazine, intracranial location, intensity;
Brand: OD inflammation by (RA), osteoarthritis, bleeding disorders, hemorrhage ROM before and 1
Aspilet Timing: inhibition of thromboembolic vit K deficiency, CV: Tachycardia, hr after
8am prostaglandin disorders; TIAs, peptic ulcer, acute hypotension, administration -
Classification: Route: synthesis; rheumatic fever, post- bronchospasm, dysrhythmias EENT: Fever: temperature
Func. class.: Nonopioid NGT antipyretic action MI, prophylaxis of MI, increased Tinnitus, hearing loss before and 1 hr
analgesic, nonsteroidal results from ischemic stroke, intracranial ENDO: Hypoglycemia, after
antiinflammatory, vasodilation of angina, acute MI, pressure, hypokalemia administration
antipyretic, antiplatelet peripheral vessels; Kawasaki disease. intracranial GI: Nausea, vomiting, -Hepatotoxicity: dark
Chem. class.: Salicylate decreases platelet bleeding, nasal GI bleeding, urine, claycolored
aggregation polyps, urticaria pancreatitis, stools, yellowing of
hepatotoxicity HEMA: skin.
Thrombocytopenia,
leukopenia,
INTEG: Rash, urticaria,
bruising SYST:
anaphylaxis, laryngeal
edema, angioedema
Generic: Dosage: Suppresses gastric Gastroesophageal Hypersensitivity to CNS: Headache, Assess:
Pantoprazole 40mg secretion by reflux disease this product or insomnia, asthenia, -CDAD: bowel sounds;
Frequency: inhibiting (GERD), severe erosive benzimidazole fatigue, malaise, abdomen for pain,
Brand: ODAC hydrogen/potassiu esophagitis; insomnia, somnolence swelling; anorexia;
Pantoloc Timing: m ATPase enzyme maintenance of long- GI: Diarrhea, diarrhea with
6am system in gastric term pathologic abdominal pain, blood, mucus.
Classification: Route: parietal cell; hypersecretory flatulence, -Serious skin
Func. class.: Proton IVTT characterized as conditions. pancreatitis, weight reactions: toxic
pump inhibitor Chem. gastric acid pump changes epidermal
class.: Benzimidazole inhibitor because it INTEG: Rash META: necrolysis,
blocks the final step Hyperglycemia, weight exfoliative
of acid production gain/loss, dermatitis: fever,
hyponatremia, sore throat,
hypomagnesemia, fatigue, thin ulcers;
vitamin B12 deficiency lesions in the
MS: Myalgia mouth, lips
-Rhabdomyolysis,
myalgia: muscle
pain, swelling of
affected muscles
Teach patient/family:
-To report severe
diarrhea; black, tarry
stools; abdominal
pain; product may
have to be
discontinued; do not
treat diarrhea with
OTC products without
approval of provider
(CDAD)