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Dr. Vijay Marakala, MBBS, MD.

Assistant professor
BIOCHEMISTRY
SIMS & RC
Cell
Introduction
membrane

Subcellular Membrane
organelles Transport
Structural
and
functional
unit of life
Major components

Cell membrane

Cytoplasm with organelles

Nucleus
Nucleus

Endoplasmic Reticulum

Animal Cell

Mitochondria

Cell wall
Plant Cell
PROKARYOTES – NO WELL
DEFINED NUCLEUS
• Chemical composition

Lipids Proteins Carbohydrates

Phospholipids Integral
Glycoproteins
proteins
Glycolipids
Peripheral
Glycolipids
Cholestrol proteins
Phospholipids Glycolipids Cholesterol
Peripheral protein

Integral proteins
• Play a key role in cell-cell recognition
– ability of a cell to distinguish one cell from
another
• antigens
– important in organ &
tissue development
– basis for rejection of
foreign cells by
immune system
Defect in Cystic fibrosis
transmembrane
regulator (CFTR) protein
Cystic
Fibrosis
A Cl transporter
Describe the
Describe the Describe the
Fluid mosaic
composition functions of
model of
of Cell plasma
Cell
membrane. membrane.
membrane.

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