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FUNCTION
DNA
TRANSCRIPTION
REVERSE TRANSCRIPTION
RNA TRANSLATION
PROTEIN
RNA REPLICATION
www.tokresource.org
RIBOSOMES
http://hyperphysics.phy-astr.gsu.edu
http://ridge.icu.ac.jp/biobk/BioBookCELL2.html
RIBOSOMES
Ø Can be found in both prokaryotes and eukaryotes
Ø Eukaryotic ribosomes are slightly larger than
prokaryotic ones
Ø Structurally consist of a small and larger subunit
Ø Biochemically consist of ribosomal RNA (rRNA) and
some 50 structural proteins
Ø Free ribosomes or as a cluster on the endoplasmic
reticulum
Ø Catalyze the synthesis of protein
ENDOPLASMIC RETICULUM
http://micro.magnet.fsu.edu
ENDOPLASMIC RETICULUM
Ø Smooth and rough ER
Ø Forms the outer bilayer of the nuclear
envelope
Ø Protein processing and lipid biosynthesis
Ø Regulate the cytoplasmic Ca2+
concentration
Ø Very dynamic; continuous bidirectional
traffic between ER and Golgi apparatus
GOLGI APPARATUS
http://jc-
biology.blogspot.com/2011/02/st
ructure-and-functions-of-
organelles.html
PROTEIN TARGETING
http://bass.bio.uci.edu
http://www.fastbleep.com
MITOCHONDRIA
• Primary role: to produce
90% energy (ATP) via
oxidative
phosphorylation.
• Mitochondrial
dysfunction à defect on
oxidative
phosphorylation, usually
coincides with the
occurrence of excess
Reactive Oxygen Species
(ROS) production
àoxidative stress
MITOCHONDRIA
LYSOSOMES
http://micro.magnet.fsu.edu/cells/lysosomes/lysosomes.html
LYSOSOMES
http://www.biology4kids.com/files/cell_lysosome.html
http://bioserv.fiu.edu
PEROXISOMES
http://micro.magnet.fsu.edu/cells/peroxisomes/peroxisomes.html
Lysosome and Peroxisome
Campbell, Neil and Jane Reece, Lisa Urry et al. Biology, 8th ed.
Pearson Education. 2008.
CYTOSKELETON
Microfilaments
solid protein (actin) which is assembled at
one end and disassembled at the other end
maintain cell shape by resisting tension (pull)
used in cell division
muscle contraction
http://www2.le.ac.uk
tvesper.blogspot.com