Professional Documents
Culture Documents
Digestive System – consists of the digestive tract / gastrointestinal (GI) tract (oral cavity, pharynx,
esophagus, stomach, small & large intestines, & anus), plus the specific associated organs (salivary glands,
liver, & pancreas).
▪ Palate – roof of oral cavity that prevents foods from passing into nasal cavity during chewing &
swallowing; consists of hard palate (anterior) & soft palate (posterior)
o Uvula – posterior extension of soft palate
o Tonsils (Discussed already in Chapter 14. A fast recall can be done.)
▪ Salivary Glands – produce saliva & consist of three major pairs: (See figure 16.7)
o Parotid Glands – largest; located anterior to each ear where parotid ducts enter oral cavity
adjacent to the 2nd upper molars
o Submandibular Glands – felt as soft lump where submandibular ducts open into the oral
cavity on each side of the frenulum
o Sublingual Glands – smallest & primarily mucous secretions where each gland has 10- 12
small ducts opening onto the floor of oral cavity
Saliva – mixture of serous & mucous fluids that is secreted at rate of approximately 1L/day which is
regulated by ANS, primarily the parasympathetic nervous system; has many functions that include:
▪ helps keep the oral cavity moist
o Mucin – a proteoglycan from mucous secretion that gives a lubricating quality to the
secretions of glands
▪ contains enzymes that begin the process of digestion (See table 16.1)
o Salivary Amylase – breaks down starch
▪ prevents bacterial infections in mouth with a mildly antibacterial enzyme called lysozyme
▪ neutralize pH
Mastication / Chewing – begins the process of mechanical digestion, breaking down large particles into smaller
ones.
Pharynx – only oropharynx & laryngopharynx carry food to esophagus (Discussed in Chapter 15. Do a
recall.)
Esophagus – muscular tube (about 25 cm long) that passes from pharynx to stomach; contains vital
sphincters:
▪ Upper Esophageal Sphincter – located at upper ends that regulate the movement of food into
esophagus
▪ Lower Esophageal / Cardiac Sphincter - located at lower ends that regulate movement of food out
esophagus
Secretions of Stomach:
▪ Hydrochloric Acid – produce pH of about 2.0 (acidic) that kills microorganisms & activates the
pepsin
▪ Pepsin – active form of pepsinogen that breaks down protein
▪ Mucus – forms thick layer that lubricates & protects epithelial cells from damaging effects of acidic
chyme & pepsin; secretions can be stimulated by stomach irritation
▪ Intrinsic Factor – binds with vitamin B12 to be readily absorbed in small intestine
Phases of Regulation of Stomach Secretions: (See figure 16.11 & table 16.2)
Both involve nervous (CNS reflexes integrated within medulla oblongata & enteric plexus) and hormonal
mechanism.
1. Cephalic Phase – “get started”; stomach secretions are increased in anticipation of incoming food
2. Gastric Phase – “go for it”; greatest volume of gastric secretion occurs due to presence of food in
stomach
3. Intestinal Phase – “slow down”; inhibits gastric acid secretions as the acidic chyme enters into
duodenum
Hormones Functions
Gastrin enters blood & carried back to stomach; stimulates additional secretory activity
Histamine enters blood to stimulate gastric gland secretory activity; most potent stimulator of HCl secretion
Secretin released from duodenum in response to low pH; inhibits gastric secretions
Cholecystokinin activated by fatty acids & peptides in duodenum; inhibits gastric secretions
You will answer and rationalize this by yourself. This will be recorded as your quiz. One (1) point will be given
to the correct answer and another one (1) point for the correct ratio. Superimpositions or erasures in your
answer/ratio is not allowed. You are given 20 minutes for this activity.
Multiple Choice
1. Which one of the following represents the correct order through which food passes in the digestive tract?
a. mouth, pharynx, esophagus, stomach, large intestine, small intestine
b. mouth, esophagus, pharynx, stomach, small intestine, large intestine
c. pharynx, mouth, esophagus, stomach, large intestine, small intestine
d. mouth, pharynx, esophagus, stomach, small intestine, large intestine
e. mouth, pharynx, esophagus, small intestine, stomach, large intestine
ANSWER: D
RATIO: In the mouth, saliva acts to start breaking down carbohydrates with the help of the enzyme amylase. It then passes to the
pharynx down to the tube called esophagus controlled by muscles that helps food to travel into the stomach. The stomach coats the
Food with a mixture of acid and digestive enzymes down to the small intestine and in the large intestine.
3. Which of the following phases of swallowing involves the epiglottis covering the opening of the larynx?
a. Voluntary phase
b. Esophageal phase
c. Pharyngeal phase
d. None of these are correct
ANSWER: C
RATIO: The tongue closes the oropharynx during the pharyngeal phase. The nasopharynx is sealed off by the soft palate and proximal
pharyngeal wall. The laryngeal aperture is closed up by the vocal cords and arytenoids, and the epiglottis swings down to cover the
laryngeal vestibule. These activities isolate the pharyngeal cavity from the airway.
6. Which of the following hormones does not inhibit gastric gland secretions?
a. secretin
b. gastrin
c. gastric inhibitory peptide
d. cholecystokinin
ANSWER: B
RATIO: Gastrin is found in the stomach and promotes the secretion of and hydrochloric acid by the gastric glands. The arrival of food
in the stomach stimulates the production of gastrin. The secretion is stifled when the pH is too low.
7. Which of the following does not occur during the gastric phase of gastric secretion?
a. Gastrin begins to be secreted by the lower part of the stomach.
b. Hydrochloric acid and pepsin secretion are stimulated in the upper and middle parts of the
stomach.
c. Peptides stimulate the secretion of gastrin.
d. Tactile sensation of food in the mouth sends nervous impulses to the medulla oblongata.
e. All of the choices are correct
ANSWER: A, B, D
RATIO: Options A, B and D are not the activities that will occur during the gastric phase of gastric secretion. Only Option C
or the peptides stimulate the secretion of gastrin will occur.
8. The medulla oblongata controls gastric secretion both by the parasympathetic branch of the nervous system
and the endocrine system.
a. The statement is true.
b. The statement is false.
ANSWER: B
RATIO: The medulla oblongata is a nervous system structure only and does not have endocrine function.
9. The anterior chisel-shaped teeth that are adapted for cutting are called:
a. incisors
b. canines
c. premolars
d. molars
e. wisdom teeth
ANSWER: A
RATIO: Incisors are teeth found in the front of the upper and lower jaws that are used to scrape or break food into smaller pieces.
LESSON WRAP-UP
You will now mark (encircle) the session you have finished today in the tracker below. This is simply a visual to help
you
track how much work you have accomplished and how much work there is left to do. You
are done with the session! Let’s track your progress.
This activity is an effective way for you to practice and clarify the learnings. With every review test, you can see
how much content you have already learned. You have to answer the set of review questions posted below. Use the
space provided in writing your answer. After completing the answers, immediately check their work against the
provided correct answer from your Main Lesson. Correct your own answers using a different color of pen to see the
differences. To make this activity worthy, make sure to follow the instructions accordingly. Enjoy!
3. The upper, expanded part of the stomach lateral to the cardiac region is called the .
Answer: Fundus
4. Large wrinkle-like folds in the stomach lining, present when the stomach is empty, that allow for
expansion when the stomach is filling are called .
Answer: Rugae
6. This is the hormone responsible for promoting the release of pepsinogens, mucus, & HCl acid in the
stomach.
Answer: Gastrin