Unit 1 P Biotechnology Carewell Pharma

Page 1 of 27
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UNIT- I
Dein Bloteeluuooay a 20tl i buet imlunduuion

ut appü catHon.
Au.& i a huamih -ot Süma. that uses ung. Oganisn
a
Cbsolagical Sousce) as a oawmadeuial to peLodiuL neo
peLoduut
rm
OR
st Cam be Simply
deined as 1e Suiene tuat ove
L ha. Hesuuologie 9neauisqed Hot ttu. paLoduueion,
manutLattoiuhg aud uaistration D biplogicol
dougs
Somu
Je Heom biojeehDlogt uas used
ha to H iut fime by
lP
Ka neuim 14/9,
+te wa» tungasuan. Cnginew ao dsuúbeo as
fattus Ot loioieco2d
el
Aue
A to im-
to BiotethuoloA wa%
using Aimpy a pLOCM
eebuslo t0 conot neu. otngicof
fm a se pLtD det mataial
ew
Phaamutical oiotenuslangy-
buauh d Suuu Rsed
Mecdi cine
ar
Rab let
Buanh
Coups u
Ree biojeshotoay study ulatedl to
C
medswe heai
a ue hioteeluolg4- Study iojech, dt
7elakesl o Imdusy
Scanned with Camšcaniner
www.carewellpharma.in
Visit & Download Free Handwritten Notes
Page 2 of 27
3 y ello -Nuutonal BT
Gen, Aqy ullweal BT

bnuy-fou enviuon meu-al puDteLH m
a
6 BL Nasúna hioehuduzy
rm
BuDun -Denent douy
jtives oh oleausolags-
Jo foduu new plcouatetica! Cduigm &
ha
PuDou dsun)
Jo PLDdLUL Sajea,
PLnd ehtetive emoe.
mone. Shabe
duugs Sabl
lP
3 J0 manu.ACLLCUe
dbugs moje
cheaply Ceuonucal)
mone aky
aiy
4) 0 pLodu anliioHc.
el
ew
3t maúny LaO pLoduution of Aullbioie

Vaceina, tuudpultid PRLO
ten,koxmOnas,
itam
atuman qeu tiseaput
ar
43Automajed bio-Cjeenivg foa-sea.piueli c.

ageut
) JmpaLDUad paunduiti on, Of Vit B2.
C
5) Laugc Scoua prLpduuion o hutose o

imepesive. oma O
auos.
Scanned With Camscanner
Page 3 of 27
Punduuiom d lbib-pesdes iotest&yis
PLoduufon ot nsgeie plaut & auimals
pLodution of p&oto-Syatutétcrll ethttiue plauet
a
4) iubhiduasftad bad pecoduuhon
nsatn
uuman o
rm
nhouos
tD)
CenoitueePy, MDLDloual autihhoiC
eC
ha
Deme ETAma ioteehplogy sije.
nDte O ma. immboizaäon. Y
a datailed
1
lP
Cnym a t
iDLalalyrü tout u
Lapab|a of
mediaig man hiplngíta qeation
cnd conveouion
O element ivds oHLe
inteLndiate p.cuodeiet
So om to and
tto tinal pLLodunek
el
OR
Eyma. Mojeeduplsgy -s meamu

ew
modihiad en us nuth
help o motecakuology
A0 we cam SLFtug
wsdladey
ar
ADetasled nok on E Lmubolisatitp

is deind LEigyrs
as tus, pLocES ho MOveM
Reslsting Öt Coninlna /iitng

C
Suppot ov
eTTe moleulo to a 30uid
sh. Subs|ta pane
is paned
Convettd to Pdud
Scanned With CamScanner
Page 4 of 27
a
rm
micauu ymolailse
ha
Edm
lP
paojtetom.. Lom olegesclaion
CnhaMLeo)
peLoduu is not Lowfami|ed nstt. f€u eyynie
el
PLodel
Sepasece4N om ea ma omt
ew
ar
C
Page 5 of 27
Detaied moe om metod Enym

Srobtzaion)
E m
a
inndiGzation
rm
physica ehunica
Aolbouption - Lovaleut biydiug
-Entsapmet
ncapSulattm ha COSS Uinl!
n
lP
Ahs0pti on t the pluoLess ok
bindina pusica
Ot fu Yma on-t
SuueLc
el
oCanrvnmaau
ew
Adbouphion
Arbsopt
Sn uws poteAA enyyme
ar
moleule
adhene tbid) o the S uafdle
oCautamafriy u the help ot
C
Weal renathon SuchasS

fortes
Vandn wall Dntes, eletooS fate
Page 6 of 27
foHLe, hydsusplaic bond Ou kyduogty

bod e4:C
Adnanilnga eisceducdlage
a
imple e eononical lowAua LLea
c
rm
oindig-
Cam e
Oautuit
eLycA, c0q9 atah
emaed weau tpecs
ha
Enduapmemd
n us PLLo , En7yma ane held
lP
ensapped ttin Su faol e
Jels o tbsOR
n
el
M. ane +apped imeida. ttte

Ca u
e mas
ew
atti ce ya
matsi
ar
the sie ot the

Seained
Pore is Such enTme js
P6odut
nitOle HSusfto4e
C
molecule passsough
Scanned with CamScanner
Page 7 of 27
watt nsothle
Fon s a -Po yaiGmiaaSiad e-fe
Othesape oF enttaymeut
a
Some
)ENne 'mlusion a fbe
rm
- Cellaoge
)Enma Imclusion m mícsoLapcule
ha
Eyme_ ane ensapped nsida
micoCapsule matsi
lP
3)EnCapsu tatiom
us
3m Hpe ob entsa-pmeel, m
osch e enyme moleue asne
el
Negulauh fatte p m aLAD US

ew
med tm S Ch utie enclosd

1 Sem penmE alo|e membtanO
Sho me.mbtana mast he poumOu
ar
poidal hon lo i in
C
Page 8 of 27
poe
:
a
() covalert onding
rm
n +is merhodl, tue en me moleule
adhae matri
ha
by Fomin Covalent bond
The Funciona 9Toup tat ma

lP
aue pau in bindinnq CndngG
6ouP coobon asoup, hydror

hydroi
sop
el
phe nolie ttsol 96OUp

ew
covaluu- bond
ZZZIZIZ/LAnmei
Aduantag- Diccaclaulay
ar
-Cuoug) m t6ULA
fonte. bfw ehz me & me MaY
is SD Stsonnq
Oe
C
Cavi Cause (os oO

that no leaka4e
enama
E-cetlulose
Page 9 of 27
0 linun-Sn tus metod,

CsosS- Ung aae O9LTNEAbetween
eM CSoUd 9tuppovt
nDeCSoud
a
neausred).
rm
sed poly funtiona 2eageut Cuh
as alutatde.de diazoberdie,
e
ha
whsh aeaet wtu enyfme
C
molee a foTm +us
Cimuiua.
lP
(w Enme
Pol tutoua
el
0aaeMt
ew
Aduata9e
ar
M mo Stoovg oDndi
tühy & able CPttenup)-
C
Siple e Cosh ethceliv
Scanned with Camscanner
Page 10 of 27
DisodWantege-
mCLy CavSe Some Cuaa ty
a
de natunaKon
rm
guo fsomezas
PeesvM anidaA
A dsanaption
ha Eurapmod
E
lP
Cauie
el
}shilisato
ew
ntapsculafoy
ar
CDS Gullfua.
Covaau
C
bondn
Scanned with CamScannër
Page 11 of 27
Appkscotlion
-Ld tn tl PRLadlsoion uH biofic Cpeusln)
CeplaloSpooi eC steseidy
a
Aorcel Amylase Cimm dhiyed) )-
rm
used n the Pood O quDK
Shareh
penstun a Cose Used m psduch
Se
ha
SuudtuAC peusu
lP
Used M. analuytieCal
appcatjom
estimatHon
oiochouscal O
Se veral
el
COmpounls
ew
ar
C
Scanned with Camscanner
Page 12 of 27
Deti ioseu07 wsije ir patijplo wouliuy &
A io seusO4, U an aualtical deuste Coinaiuing an
a
iTnbiUtd hiplogita) maycuiale u, antiliofc ef <)
rm
PLOduuL
peuital duemdtaf , eledsical Sigual +Aat Cam
be measUOed
ORK
ha
L ana Htuose anautica deuse edeh asu
sed to clauGe olagttal uspouse l a
elettiea nal
lP
BiosemgdAUs aa alo sed jo:4 deteung ttuL cone
oy Susamua ckundta&otas bhalncal paLaanial
el
BiosesOL COurfs of maim pauH-() BioreLap tO

9Foaunduen.
ew
Eletiical Eleutuous BOse0

leduo chewsca .Bioteus0
ar
3) Optica biose@
4)oseawimauc hioseuso
C
5)PHo eleii Seng07

)Piooetesdase bioSeuso
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Page 13 of 27
Piuspke -
Raed on te pinuwple o na
teLudukion
WOLdug- ewuy' hioseulOt lompu
a
hologt L conupouAmt uat a +te Seuuon
rm
An eleclous compoNOM taa dateT o*ecs
gmal
Cos-lior)-
ha
)Bioement/Bio LeALpttaneuaos
TuMS dLLoy
3) Arupbtie
4) PLDLeKON
lP
5 Ddspka Lust output
pi yen PLD AMOP
Ay Drploy
el
Atuabyte
Tadun
bloelemu sla umt.
ew
Aymalte-34 woce ton

atompoMa, uose,
.
Bua 9liuuo UsOa dougCoL has
mas be
he meaAud
measud
e4 C
Blocjememt- Ahis
elonut um wlith Qualo boue.
a
ar
Eg use, MSuLaugawm,
Ouganelles.
Suanibdun- t a deuihe, tuo LOmuLLti enLt
Om ok OLUm fO CUuDtece enly
C
osum.
Euhau. l 8gral
Scanned
-.
with Camscanner
Page 14 of 27
LLDAS-aualiyte :ltue Sinal o. thovmd a ou-tpud
Dirplaa
tSllotts flte Dulpeld
a
Stow aauuoueUY woLlles
rm
Aualyte +Boluo.gitn matesmal
Bound aualyfe
Brolegtca
9tspote
ha
By trauteleten
lP
Eewne nesfpoue Mgua
Elauue Chy aupoyi)

el
Tom otpu+| Cby psocexsOn)

ew
1Output>deploy LL
Hppicoclion
ar
1) Pood imdusij - uscol to deleet at

paitageus in joo
Eyucilit. hlascuso ouu.
daie itduley
C
Maditalcal fiekd- Gluuu

laioseusaythe, dablis
ets tdu l icgrua.siscd
Jwuwnuitu dace ftta fcuupteenkeane
Page 15 of 27
PPaAaau kit DNA iosens08
DuL distovu Ea duuua auaiyis- E ma
bastd
i o SesOL CO be ap plied in +ta plauaLuLle ca
imdusy tOA moitoing clumital
a
pauamul
m u punduh om pauauiin
rm
EnvEnuiLonmedal mowdoring BOSemsox haua wwde
Ppicadm to mnsjemonct efinaion
CoulLuSl o watua
/A0i & ai contamnan
ha
|5) tuuose monlo.bug
) Sreeuug ot ASSeaM
lP
) veeubuast aqusuutmuak applEaaK on
s) cisc aalytis
el
QExploint metas ob pLoduton of

1-Aaag 2 Coulalae PenuSuare
ew
F
AMukas- Anuylase a mpoul-oM. lugouuolan: en
enyg
he h have. bee.n nusdely sed iuu Ma dsacles -
o
ar
3 tp a- oAmualuyh
b-B hmaluyne
C- ualyse.
I'nduion k-
C
metinds
a Submengd tmeulahon $N
CSSP
soli Stt nttin
Page 16 of 27
Submeugud mentation CSMP)

SHE eploys
Sue a
nee tlouting liquid tttastte. sulbsjsaluy
ma mold'sscs and buot.
a
a Jhe puodu4 Yictdlad tm jmweutati on iSccmeleo
rm
b Heeumemtatim buoth
3) 3hahementaion
ltehine Swtab] bo
uLDUgai Sm Such c
uiga moiguus buceia tuat. ucqun
tOueuk ouCuin
9-sout.
ha
) Jlu niLod cusd ba Ht« Cu4oaLion oF
Sccoudasuy meabouiu I&al
ALLLd-a he
scd in
iuis toum
lP
Aduaula j
Jt ia uo. meHnc wtuueh atow -ta uubyati
O5 qenial,
mod d ougumim
el
tudu ssf
Sue SHtsucitton D
emedim pusihic
ew
PLoe o tuend p.euodeett cc oe

easi dona
conu
ar
Ot PTDCeM poaety
Gu Hep H aenefom,
NOISUn, Can be olon Convi entH
C
Page 17 of 27
otL Slals oumentelion (SSP)
SSf S mutLod use_d Go muLohuy
wuih tarine les - mois/ule ConeM:
uin arowth
a
rm
Jhe SoGd Sttbseot Subsrade commonly
in ttus,metuod a
-sa
ha
bagak2
Papa pulp:
euaiog
Jhiu
lP
was R mastiad
Cc be ecA
7eeled used as
Substs ade i Hus mattuod
SSF
el
SNS COA mply

equposb, Riglus PALDdu
ew
naion,
)Catalyu- Coutan au
pLoduLLo byH a CLeoie SceOLLgusw
ar
2 uumal Vegtake. celu.

CLM
euHto ulLiel catale
C
tLe osOnsONmaßn o ydungem p.eoide
Page 18 of 27
Calalane t cotaua fet ís

4o duet
buete
a
Pusupote
rm
) 1deutificaHm o
9aom popjius &
LaM megetfua, Deeg.austu.
S1
a peimau, Hest wed m tl dithownHafm
Or tepualocod tanaud Sisea-ptoco
ha
Ao im dKeuHaHg ao a obliqa ti
anaeneid bauuta
Puoteduro
lP
Plaua a mau amout of batal
Colo CI to ay hu) on a claoa glas
ide
el
Aeld
)Add OLo toa dop
3 hydsogen
penoU do
ew
3) Posue Raptol bubble formatie

RElt
Negeiua No buhlole toRMatfm
ar
C
Page 19 of 27
peniu inase- Tis Can be de

broady olasjied into 2 pooLasAey
upstaaunaMg puOt
a
na Rees to tue
rm
PeLOLLMe befone mput tothe feamente
encom pass a
leady
teehunlg tCuct
to ttte. CyuttaSis
O Psoduct
Imcduda,
ha
tue. exptoLeation, developmet
D LLOd dction
DOwn.Stzjea n pgoceniu
lP
Reeus. to DaLOCLMU
-
dono to puib t Output oh tte

enmentca unHj it 1eathes. fo tLa
el
dlesnned psodut
Ftow chau)
ew
Medium o pLodusiom
Hea s1eliation
ar
Pementalloy
C
Seed coltue
Page 20 of 27
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***
Remmoval O biomass
Adding of solveut
a
rm
eenbisual etsa tiop
entsauo
Fuid boed ha
duiug
lP
SOaae
el
dohination
Mediwm
ew
fo pud- Cabon s0unu

Co Steep uD1 guuse.
Hea Stessigaiem mediwn s
ar
-
Sfese
OS Lally
siougt a hodiua tbe On 3teo yed
C
wttt FtLe fejmeutn
.
Scanned with CamScañner
Page 21 of 27
fenmendation 4+ is done ma fe.d- batc

modo. as qlunoge mus not be addod
m wg amount ah heging
tta Of
a
sowh Hemup- shoutd he 30-9c
rm
wti le PH-
Ptm (1.02)
ha
RPm 200
Seed C n 7lu add seed

y
lP
C U, is deueloped in las
addHam 9 Of pelin Spotes
mto a oel medsm & Wen
el
f i soon tote aCcepteble

iU be moculated
ew
Qmoun
nto HCLn ermente
emoval ok omay ary
ar
fi tersoation ecee a
o Se parafHom
C
ttis poit
tsSaDvi ed oe mdve
io aM fsomtt cutune
Page 22 of 27
Soh as tuugus
-POHaTy vacwm Lte is uwled
a
Adsun Solvem
rm
n dd) to dissolue tta pemity
Psesemt in ttu eak, sowemt
addad
CeMtifuge ha
etsadior
lP
Is done to Separsate ttu So
Fsom COmponeu
Tulbulas bou is
el
ed
Etrautto)
ew
penitl dsotoe iml Soluent

CLUdeAO
etraLtonto bfain bette)
ar
P tu peuGUn psaduaos
C
Page 23 of 27
Fluld bed dsun Puug is nuesay
to nemo ve ay semaiusng otsfuUg
a
psesen ntle powdAnEd peusllM
rm
Stosage- Stosd m conaluo
tuept im detad euuiH on meu
ha
lP
PLDin enginuingsut uote,
3 a metod o chaugiua
to a chieve
a psofein
Seapene dasied
el
2Lsuult, Such as a
chanog m
ew
Substa te speAict. o sjnito

Stahii h o ttio femp gaui
ar
SoLvent *
aud0 /entreamas
Ot pt
C
Page 24 of 27
pLOfein egis +ta Coneption

PLDd o bnatueal PDpePtalo
oug modi ticohem
a
lem Ob
aLniu
rm
aLd SeaeMLA Hat
tound n natus
Stuais n
ha
Of
PLLofeim
Buud o use o e tombi not

lP
DN leaualo to cawag aui uo
geoueLe
el
Ol etive-
Ceoute a Speslan
ew
enypne fo
Catalay Pood o hiq
va
Ot 9pehi c ebeui cl
ar
PoL0dAhon enYHme
in Jag
qLantitiu
C
PLodse0a rolegtta Compo ond

ne tlutie PepAde e
Page 25 of 27
Applicodog -
a) Envi omeutal applicotion-

emtc metuooly fou clusdrutna. o6
a
mitOtnq ¢ms , elininae Fua enuiyonmetal
rm
Potuuion
peuoleum hioeining.
ha
)MedJcal appücato.n-
CamLon R0acdmant-
Roolio mnb-fuoraP
lP
elauno - loitsleeuolusgy.
d) Redo pLOteln h eu mo
el
BioBlopolmAn puod on
ew
Gentic Emainesng
Deuganw'Sss
oces of ChoLMgng C
ar
genenc Mateva to prodiee a

new Usetu esut
C
Page 26 of 27
'g Ceecr:fe.ed Cy)
a
rm
-eotOCENILUSErVe
A
ac{cri uy
ha
CLLdpey
lP
5) 3u. 9Cu is 1n.sestcd inulo
plasmd
el
ftu
6) Jhe etiCallo ataed

ew
plasmiel is mševted ato a

btuteum
ar
ppi cation-
Malliu medine
C
matuia plauts J0sct

sease
Page 27 of 27
a
rm
ow Cells te tarl -in - OLLga SEae
ha
4**
an envistopig
lP
Spidi ot
emVAiayom houom tu 00Tmn
el
pLoun odjument b pp
ew
te CoO duattd rulaq euOISIS

ar

C

Unit 1 P Biotechnology Carewell Pharma

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Unit 1 P Biotechnology Carewell Pharma

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Page 1 of 27

Carewell Pharma - A Family of Learning

Dein Bloteeluuooay a 20tl i buet imlunduuion

Gen, Aqy ullweal BT

3t maúny LaO pLoduution of Aullbioie

43Automajed bio-Cjeenivg foa-sea.piueli c.

5) Laugc Scoua prLpduuion o hutose o

Eyma. Mojeeduplsgy -s meamu

ADetasled nok on E Lmubolisatitp

Reslsting Öt Coninlna /iitng

Detaied moe om metod Enym

Weal renathon SuchasS

foHLe, hydsusplaic bond Ou kyduogty

M. ane +apped imeida. ttte

the sie ot the

Scanned with CamScanner

Negulauh fatte p m aLAD US

med tm S Ch utie enclosd

Scanned with CamScanner

The Funciona 9Toup tat ma

6ouP coobon asoup, hydror

phe nolie ttsol 96OUp

Cavi Cause (os oO

0 linun-Sn tus metod,

Siple e Cosh ethceliv

Scanned with Camscanner

Scanned with CamScannër

Scanned with Camscanner

Deti ioseu07 wsije ir patijplo wouliuy &

A io seusO4, U an aualtical deuste Coinaiuing an

BiosesOL COurfs of maim pauH-() BioreLap tO

Eletiical Eleutuous BOse0

5)PHo eleii Seng07

Scanned with CamScanneer

Aymalte-34 woce ton

LLDAS-aualiyte :ltue Sinal o. thovmd a ou-tpud

Elauue Chy aupoyi)

Tom otpu+| Cby psocexsOn)

1) Pood imdusij - uscol to deleet at

Maditalcal fiekd- Gluuu

Scanned with CamScanner

QExploint metas ob pLoduton of

Submeugud mentation CSMP)

PLoe o tuend p.euodeett cc oe

Scanned with CamScanner

SNS COA mply

2 uumal Vegtake. celu.

tLe osOnsONmaßn o ydungem p.eoide

Scanned with CamScanneer

Calalane t cotaua fet ís

3) Posue Raptol bubble formatie

Scanned with CamScanner

peniu inase- Tis Can be de

dono to puib t Output oh tte

Scanned with CamScanner

fo pud- Cabon s0unu

wttt FtLe fejmeutn

fenmendation 4+ is done ma fe.d- batc

Seed C n 7lu add seed

f i soon tote aCcepteble

penitl dsotoe iml Soluent

Scanned with CamScanner

Fluld bed dsun Puug is nuesay

to nemo ve ay semaiusng otsfuUg