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Integumentary system - consists of the skin, its accessory structures such as hair and sweat
glands, and the subcutaneous tissue below the skin.
Skin - is made of several different tissue types and is considered an organ.
Keratinocytes - a cell of the epidermis that produces keratin, is formed in the basal epidermal
layer above the dermis.
Melanocytes - A type of pigment cell that, in particular, produce melanin, and occurs in the
epidermal layer of the skin, in the uveal layer of the eye, the inner ear, the meninges, the heart,
and the bones.
Merkel cells - also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped
mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.
Langerhans cells - are tissue-resident dendritic cells of the skin, and contain organelles called
Birbeck granules. They are present in all layers of the epidermis and are most prominent in the
stratum spinosum.
Exocrine gland- glands that secrete substances onto an epithelial surface by way of a duct.
sebum – a yellowish, oily substance secreted by the aptly named sebaceous glands that are
found on nearly every surface of the body
Arterioles are small arteries, and the smooth muscle in their walls permits them to constrict
(close) or dilate (open). This is important in the maintenance of body temperature.
Collagen - the most abundant protein in your body. It is the major component of connective
tissues that make up several body parts.
2. Dermis (the inner) - s is made of an irregular type of fibrous connective tissue, irregular meaning
that the fibers are not parallel, but run in all directions. Fibroblasts produce both collagen and
elastin fibers.
Integumentary System
Skin Derivatives/Appendages
2. hairs
3. nails
- bacterial damage
- UV radiation (sunlight)
4. Synthesize vitamin D.
1. epidermis
2. dermis
5 layers
1. Stratum basale
2. Stratum spinosum
3. Stratum granulosum
4. Stratum lucidum
5. Stratum corneum
Types of Skin Cells in the Epidermis
Types of Melanin
MELANOCYTES
Dermis – a strong stretchy envelope that helps to hold the body together.
2 Regions:
1. papillary layer
2. Reticular layer
Papillary Layer
have house pain receptors (free-nerve endings) and touch receptors (meissner’s corpuscles)
Reticular Layer
Contains blood vessels, sweat and oil glands, and deep pressure receptors (pacinian corpuscles)
Has elastic fibers (gives skin its elasticity when we are young)
Cutaneous Glands
- all exocrine glands that release their secretions to the skin surface via ducts.
Types
Sebaceous Gland (oil gland) - secretes a mixture of oil substances and fragmented cells that serve
as: 1) a lubricant and makes the skin soft and moist; and 2) prevents the hair from becoming brittle.
Three regions:
3. cuticle – heavily keratinized, provides strength, helps keep the inner hair layers
tightly compacted.
Three Regions:
1. free edge
2. body
3. root
Integumentary System
Integumentary system - consists of the skin, its accessory structures such as hair and sweat
glands, and the subcutaneous tissue below the skin.
Skin - is made of several different tissue types and is considered an organ.
Keratinocytes - a cell of the epidermis that produces keratin, is formed in the basal epidermal
layer above the dermis.
Melanocytes - A type of pigment cell that, in particular, produce melanin, and occurs in the
epidermal layer of the skin, in the uveal layer of the eye, the inner ear, the meninges, the heart,
and the bones.
Merkel cells - also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped
mechanoreceptors essential for light touch sensation and found in the skin of vertebrates.
Langerhans cells - are tissue-resident dendritic cells of the skin, and contain organelles called
Birbeck granules. They are present in all layers of the epidermis and are most prominent in the
stratum spinosum.
Exocrine gland- glands that secrete substances onto an epithelial surface by way of a duct.
sebum – a yellowish, oily substance secreted by the aptly named sebaceous glands that are
found on nearly every surface of the body
Arterioles are small arteries, and the smooth muscle in their walls permits them to constrict
(close) or dilate (open). This is important in the maintenance of body temperature.
Collagen - the most abundant protein in your body. It is the major component of connective
tissues that make up several body parts.
4. Dermis (the inner) - s is made of an irregular type of fibrous connective tissue, irregular meaning
that the fibers are not parallel, but run in all directions. Fibroblasts produce both collagen and
elastin fibers.
Skin Derivatives/Appendages
2. hairs
3. nails
- bacterial damage
- UV radiation (sunlight)
4. Synthesize vitamin D.
1. epidermis
2. dermis
5 layers
6. Stratum basale
7. Stratum spinosum
8. Stratum granulosum
9. Stratum lucidum
Types of Melanin
MELANOCYTES
Dermis – a strong stretchy envelope that helps to hold the body together.
2 Regions:
1. papillary layer
2. Reticular layer
Papillary Layer
have house pain receptors (free-nerve endings) and touch receptors (meissner’s corpuscles)
Reticular Layer
Contains blood vessels, sweat and oil glands, and deep pressure receptors (pacinian corpuscles)
Has elastic fibers (gives skin its elasticity when we are young)
Cutaneous Glands
- all exocrine glands that release their secretions to the skin surface via ducts.
Types
Sebaceous Gland (oil gland) - secretes a mixture of oil substances and fragmented cells that serve
as: 1) a lubricant and makes the skin soft and moist; and 2) prevents the hair from becoming brittle.
• Two Divisions
3. cuticle – heavily keratinized, provides strength, helps keep the inner hair layers
tightly compacted.
THE STRUCTURE OF A NAIL
Three Regions:
1. free edge
2. body
3. root