ACTIVITY SHEET IN SCIENCE (SPECIALIZED SUBJECT-STEM)

QUARTER / DOMAIN
WEEK & DAY LC CODE
GRADE
NO.
LEVEL
STEM_BIO11/12 -
2nd QUARTER/ GENERAL
WEEK 8 IIa-j-1
GRADE 12 BIOLOGY I
DAY 1

Name : ________________________________________ Grade & Section: ________________

TOPIC: ATP-ADP Cycle
LEARNING COMPETENCY: Explain coupled reaction processes and describe the role of ATP in energy
coupling and transfer.

Activity No. 19
ATP-ADP Cycle

I. OBJECTIVES

1. Describe the structure of ATP.

2. Explain the phases of the ATP-ADP cycle.

II. LEARNING OVERVIEW

Cells require constant supply of energy and use energy-rich molecule, Adenosine Triphosphate
(ATP), to perform nearly all of its activities. This explains why ATP is tagged as the energy currency of
the cell.

In addition, each ATP is made up of a sugar ribose, a nitrogen-containing base adenine, and a chain
of three phosphate groups. The energy is released when the bond between the second and third phosphate
is broken by addition of a water molecule in the process called hydrolysis, a molecule of inorganic
phosphate leaves the ATP, which then becomes Adenosine diphosphate or ADP.

The repetitive breakdown and regeneration of ATP is known as the ATP-ADP cycle. In this activity,
you will look into the structure of ATP and trace the phases of ATP-ADP cycle.

III. A. MATERIALS:

pen and paper

B. REFERENCES

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 Rea, Maria Angelica D. et. al. (2017) General Biology I. Rex Book Store, Inc. pp. 160-162
https://www.khanacademy.org/science/biology/energy-and-enzymes/atp-
IV. PROCEDURE

A. The Structure of Adenosine Triphosphate (ATP)

1. Use the color code below and shade the components of ATP accordingly.
Components of ATP Color
Adenine blue
Ribose red
Phosphate Group yellow
2. Label the parts accurately.
3. Determine the area that represents high energy bond and encircle using red ink.

3 2 1

1 2 3

Figure 26. Structure of Adenosine Triphosphate

B. ATP Decomposition: ATP ADP

1. Use the color code below and shade the components of energy molecule.
Components of Energy Molecule Color
Adenine blue
Ribose red
First two Phosphate group yellow
Lone Phosphate group violet
Energy Released green
2. Label the parts accurately.
3. Determine the area that makes up one molecule of ADP and encircle using red ink

GY
N ER ED!
E AS
LE
RE

Figure 27. ATP Decomposition

C: ATP Synthesis: ADP ATP

1. Use the color code below and shade the components of energy molecule.

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 Components of Energy Molecule Color
Adenine blue
Ribose red
First two Phosphate group yellow
Lone Phosphate group violet
Energy Absorbed orange
2. Label the parts accurately.
3. Determine the area that makes up one molecule of ATP and encircle using red ink.

ENERGY Absorbed

Figure 28. ATP Synthesis

D. Fill-in the blanks to complete the narration about ATP. Use the keywords in the box below.

eukaryotic bacteria phosphate ATP organisms

nutrients rechargeable ADP energy ADP
ATP low Peso cycle
Animalia reattach ADP Mitochondria

The ATP-ADP (1)____________is one of the most important processes among living things.
It occurs in the powerhouse organelle called (2) _____________ present in (3)_____________cells.
ATP is the primary (4)____________molecules for all (5)____________. In other words, everything
alive depends on (6)____________for energy, from the simplest single-celled organism,
(7)____________to the most complex organism in the Kingdom (8)____________.

Think of ATP as a (9)____________ battery, while its sister molecules, (10)____________ is the
same battery but (11)____________ in charge due to its missing P or (12)____________ group.

There is a need for a sufficient supply of energy from (13)____________ obtained from the
food we eat. Third phosphate will(14)_____________ to (15)____________ and make source of
energy available to the body. We can compare it to (16) ____________ currency of the Philippines .
If you have U.S. dollar, it has value, but local businesses and stores won’t accept that method of

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 payment. You need to first take the foreign currency to a bank (17)(____________) to exchange it for
Philippine Peso (18) (____________).

V. ANALYSIS

Q1. What happen when the third P is removed from ATP?

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Q2. How ATP stores energy?
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Q3. Why regeneration of ATP is important in cells?

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Q4. How the process of dehydration and hydrolysis take place in ATP-ADP Cycle?
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VI. GENERALIZATION

Describe the phases of ATP-ADP Cycle?

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VII. APPLICATION
While you are in a vacation in Bohol, one summer night, you join in a group firefly watching
tour by a boat in Abatan River, where you witness diverse fireflies are glowing briefly in the dark.
Make an inference if producing this light requires energy? If so, where might the energy come from?

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VIII. ENRICHMENT ACTIVITY

1. Cite and explain at least five (5) cell activities/processes that require the use of ATP?
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2. What are the enzymes needed for ATP-ADP Cycle to take place? Explain each role in the
process?
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