DRUG STUDY

NAME AND CLASSIFICATION DOSAGE, MECHANISM OF ADVERSE REACTION INDICATION NURSING

CLASSIFICATION OF FREQUENCY, ROUTE, ACTION AND SIDE EFFECT AND RESPONSIBILITIES
DRUG TIMING CONTRAINDICATION

ADVERSE REACTION: INDICATION:

GENERIC NAME: Pharmacologic class - DOSAGE: 25mg - It increase the - Observe 10 rights of
mineralocorticoid amounts of sodium and CNS: ataxia, confusion, - edema drug administration.
Spironolactone receptor antagonist. water to be excreted, drowsiness, headache, - essential hypertension - Monitor signs of allergic
while potassium is lethargy - diuretic-induced reactions including
Therapeutic class - FREQUENCY: OD retained. Aldactone acts GI: cramping, diarrhea, hypokalemia pulmonary symptoms and
potassium-sparing both as diuretic and as gastric bleeding, gastritis, - diagnosis of primary skin reactions.
diuretic an anti-hypertensive ulceration, vomiting hyperaldosteronism - Monitor signs of fluid,
BRAND NAME: drug. It may be given Hematologic: - to manage primary electrolyte, or acid-base
ROUTE: Oral alone or with other agranulocytosis hyperaldosteronism imbalances.
Aldactone diuretic agents which act Metabolic: hyperkalemia, - hirsutism - Assess dizziness that
more proximally in the Skin: hirsutism - heart failure might affect other
renal tubule. Other: angioedema, - to decrease risk of functional activities.
TIMING: 6pm anaphylaxis metrorhagia - Assess blood pressure
periodically and compare
SIDE EFFECT: CONTRAINDICATION: to normal values to help
document anti-
- allergic reactions - anuria,acute or hypertensive effects.
- dehydration progressive renal - Advise patients taking an
- high potassium level insufficiency,rapidly aldactone antagonist to
- kidney injury deteriorating renal avoid salt substitutes,
- low blood pressure function, or hyperkalemia nonsteroidal anti-
- low sodium level -taking amiloride or inflammatory drugs, and
triamterence foods high in potassium to
concomitantly reduce the risk of
-use cautiously in hyperkalemia.
patients with fluid or -Monitor serum
electrolyte imbalances, potassium, blood urea
impaired kidney function, nitrogen , creatinine, and
or hepatic disease. creatinine clearance level.