Microbiology for the Healthcare

Professional 2nd Edition VanMeter Test

Bank
Visit to Download in Full: https://testbankdeal.com/download/microbiology-for-the-heal
thcare-professional-2nd-edition-vanmeter-test-bank/
Chapter 10: Pharmacology
VanMeter: Microbiology for the Healthcare Professional, 2nd Edition

MULTIPLE CHOICE

1. The branch of pharmacology that addresses drug amounts at various sites in the body after
drug administration is called
a. pharmacodynamics.
b. pharmacokinetics.
c. pharmacotherapeutics.
d. pharmacy.
ANS: B REF: p. 202

2. The generic name of a drug refers to its __________ name.

a. trade
b. proprietary
c. chemical
d. nonproprietary
ANS: D REF: p. 203

3. The most rapid rate of drug absorption is achieved by __________ administration.

a. on the skin
b. intravenous
c. intramuscular
d. sublingual
ANS: B REF: p. 204

4. The decrease in blood clotting by heparin occurs at which general site of action?
a. Cellular
b. Extracellular
c. Neuromuscular
d. Intracellular
ANS: B REF: p. 205

5. Which of the following is a phase I reaction in biotransformation?

a. Oxidation
b. Conjugation
c. Acetylation
d. Glucuronidation
ANS: A REF: p. 206

6. All of the following are ways the kidney are used for urine formation and drug clearance
except
a. Filtration
b. Tubular secretion
c. Tubular filtration
 d. Tubular reabsorption
ANS: C REF: p. 207

7. The time response measures all of the following except

a. ED50
b. Peak effect time
c. Onset of response
d. Threshold level
ANS: A REF: p. 208

8. When drug receptors are maximally activated it is referred to as the

a. threshold level.
b. peak effect.
c. cessation effect.
d. latency time.
ANS: B REF: p. 208

9. A subacute toxic effect occurs when the adverse drug effect occurs
a. after 5 minutes of exposure.
b. after 24 hours of exposure.
c. after repeated exposure for days.
d. over months to years of exposure.
ANS: C REF: p. 209

10. The specific antidote to botulinum toxin is

a. sodium bicarbonate.
b. antitoxin.
c. pralidoxime.
d. naloxone.
ANS: B REF: p. 209

11. The term used to indicate the extent to which a drug reaches its site of action is
a. bioactivity.
b. bioavailability.
c. bioremediation.
d. biostasis.
ANS: B REF: p. 205

12. Drugs needed for diseases with fewer than 200,000 patients, and that fail to receive attention
for development because of cost and need, are called
a. secondary drugs.
b. minor drugs.
c. orphan drugs.
d. specialty drugs.
ANS: C REF: p. 211
 13. The discipline addressing issues associated with the choice and application of drugs to be used
for disease prevention, treatment, and/or diagnosis is
a. pharmacotherapeutics.
b. toxicology.
c. pharmacokinetics.
d. pharmacy.
ANS: A REF: p. 202

14. Drugs are excreted from the body primarily via the
a. lungs.
b. kidneys.
c. small intestines.
d. spleen.
ANS: B REF: p. 206

15. A mercury-containing compound used as a preservative in vaccines is

a. analgesic.
b. EDTA.
c. codeine.
d. thimerosal.
ANS: D REF: p. 210

COMPLETION

1. The body’s metabolism of drugs is called __________.

ANS: biotransformation

REF: p. 205

2. The study of the body’s response to poisons and their harmful effect is referred to as
__________.

ANS: toxicology

REF: p. 209

3. Drug administration, absorption, distribution, and clearance are collectively called

__________.

ANS: pharmacokinetics

REF: p. 204

4. ED50 is a measure of the __________ response.

ANS: dose

REF: p. 207
 5. The federal agency that approves the use of a specific drug is the __________.

ANS: FDA

REF: p. 211

6. The three general sites of drug action are __________, __________, and __________.

ANS:
extracellular, cellular, intracellular
extracellular, intracellular, cellular
cellular, extracellular, intracellular
cellular, intracellular, extracellular
intracellular, cellular, extracellular
intracellular, extracellular, cellular

REF: p. 205

7. The __________ effect is the combined action of intestinal and hepatic drug-metabolizing
enzymes that affects a drug’s bioavailability.

ANS: first-pass

REF: p. 208

8. A __________ name is a nonproprietary single name usually related to the drug’s relationship
to a therapeutic class.

ANS: generic

REF: p. 203

9. Drugs and substances with a high probability for abuse with no therapeutic use and a lack of
safety controls are classified as Schedule __________.

ANS: I

REF: p. 211

10. The __________ is the ratio between a drug dose causing undesirable effects and the dose
that causes the desired effects.

ANS: therapeutic index

REF: p. 207

MATCHING

Match the description below with the correct item from this list.
a. Morphine
 b. Administered into the subarachnoid space
c. Diazepam
d. Administered into muscles
e. Aspirin
f. Administered sublingually
g. L-Dopa
h. LSD
1. Prodrug
2. Schedule II controlled substance
3. Intrathecally
4. Schedule I controlled substance
5. Schedule IV controlled substance

1. ANS: G REF: p. 207

2. ANS: A REF: p. 211
3. ANS: B REF: p. 204
4. ANS: H REF: p. 211
5. ANS: C REF: p. 211