Practical Pharmacology for the Surgical

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Chapter 07 Pharmacokinetics
1. Pharmacokinetics is the term used to describe the
a. methods of drug administration
b. process for obtianing FDA approval for a drug
c. way a drug interacts with the body
d. way the body processes a drug
ANSWER: d
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

2. What is the correct order of the pharmacokinetic processes, from first to last?
a. absorption, metabolism, distribution, excretion
b. distribution, absorption, metabolism, excretion
c. absorption, distribution, metabolism, excretion
d. metabolism, absorption, distribution, excretion
ANSWER: c
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

3. The process of freeing of a drug from its administration form is called

a. excretion
b. liberation
c. absorption
d. distribution
ANSWER: b
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

4. Most drugs requiring liberation are administered

a. subcutaneously
b. intravenously
c. topically
d. enterally
ANSWER: d
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

5. If a medication has an extended-release system, it means that the drug will be

a. liberated over a prolonged period
b. liberated immediately
c. taken into the circulatory system by the arteries
d. taken into the circulatory system by the veins
ANSWER: a
POINTS: 1

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Chapter 07 Pharmacokinetics

REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

6. Absorption occurs when the drug is

a. delivered to the target cells
b. eliminated from the body
c. taken into the circulatory system
d. broken down in the body
ANSWER: c
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Absorption.

7. Most drugs enter the circulatory system by a process called

a. active transport
b. passive transport
c. pinocytosis
d. bioavailability
ANSWER: b
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Absorption.

8. The term _____ describes the amount of drug that enters the circulatory system and is available to the target tissue cells.
a. pinocytosis
b. bioavailability
c. catabolism
d. biotransformation
ANSWER: b
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Absorption.

9. The term distribution is used to describe

a. the chemical changes the drug undergoes as it is broken down
b. freeing of the drug from its administration form
c. the elimination of the drug from the body
d. delivery of the drug to the target cells
ANSWER: d
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Distribution.

10. The term _____ refers to the chemical changes that a drug substance undergoes as it is being broken down within the
body in preparation for excretion.
a. distribution
b. absorption
c. metabolism
d. liberation
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Chapter 07 Pharmacokinetics

ANSWER: c
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Metabolism.

11. If the half-life of a drug is four hours, it means that after four hours
a. only half of the concentration of the drug will remain in the blood
b. the body will have fully processed the drug, which will be ready for excretion
c. the body will start to experience the effects of the drug
d. only half of the drug will have entered the circulatory system
ANSWER: a
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Metabolism.

12. What happens when a drug is excreted?

a. It is delivered to the target cells.
b. It is freed from its administration form.
c. It is removed from the body.
d. It is absorbed into the circulatory system.
ANSWER: c
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Excretion.

13. Most drugs are excreted in the

a. urine
b. feces
c. sweat
d. saliva
ANSWER: a
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics, Excretion.

14. Pregnancy commonly causes the

a. absorption of a drug to speed up
b. distribution of a drug to slow down
c. metabolism of a drug to speed up
d. excretion of a drug to slow down
ANSWER: b
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

15. The distribution of a drug may not be possible if

a. it is administered in liquid form
b. the patient is elderly

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Chapter 07 Pharmacokinetics

c. comorbid conditions are present

d. there are no transporters available
ANSWER: d
POINTS: 1
REFERENCES: Core Curriculum under Terminology, Pharmacokinetics.

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