Azathioprine (Imuran) is used to treat rheumatoid arthritis and prevent renal transplant rejection. It inhibits DNA and RNA synthesis and purine synthesis. The dosage is based on body weight and must be determined by a doctor, usually starting at 3 to 5 mg per kg per day. Contraindications include hypersensitivity, pregnancy, breastfeeding, unknown TPMT status, malignancy, and infection. Nursing implications include monitoring blood counts regularly due to risk of hematologic effects.
Azathioprine (Imuran) is used to treat rheumatoid arthritis and prevent renal transplant rejection. It inhibits DNA and RNA synthesis and purine synthesis. The dosage is based on body weight and must be determined by a doctor, usually starting at 3 to 5 mg per kg per day. Contraindications include hypersensitivity, pregnancy, breastfeeding, unknown TPMT status, malignancy, and infection. Nursing implications include monitoring blood counts regularly due to risk of hematologic effects.
Azathioprine (Imuran) is used to treat rheumatoid arthritis and prevent renal transplant rejection. It inhibits DNA and RNA synthesis and purine synthesis. The dosage is based on body weight and must be determined by a doctor, usually starting at 3 to 5 mg per kg per day. Contraindications include hypersensitivity, pregnancy, breastfeeding, unknown TPMT status, malignancy, and infection. Nursing implications include monitoring blood counts regularly due to risk of hematologic effects.
(BRAND NAME (BASED ON CONTRAINDICATION THE SHAPE OF IMPLICATIONS/
NAME) DOCTOR’S THE RESPONSIBILITY ORDER) MEDICATION CARD APPLICABLE AND THE COLOR OF THE MEDICATION TO BE USED Imuran Azathioprine For oral dosage General Indications- - History: Allergy to form (tablets): Azathioprine is indicated azathioprine; to treat rheumatoid arthritis rheumatoid arthritis Adults— Dose and prevent renal patients previously is based on treated with transplant rejection. body weight and alkylating agents; must be pregnancy or male determined by Action partners of women your doctor. At Description: Azathioprine trying to become first, 3 to 5 is an imidazolyl derivative pregnant; lactation. milligrams (mg) of mercaptopurine which - Physical: T; skin per kilogram inhibits RNA and DNA color, lesions; liver (kg) of body synthesis, and antagonises evaluation, bowel weight per day purine synthesis. It sounds; LFTs, renal given as a single interferes w/ cellular function tests, dose on the day metabolism by inhibiting CBCsevere is of the thromboembolism. coenzyme functioning and transplant, or sometimes 1 to formation; may also inhibit 3 days before mitosis. the transplant. Your doctor may adjust your dose as needed. Contraindication: Interventions:
- Hypersensitivity. - Give drug IV if oral
Children—Use administration is - Pregnancy or plan and dose must not possible; switch be determined for pregnancy: to oral route as soon by your doctor. Contraception as possible. recommended. ... Administer in - Breastfeeding as 6- divided daily doses MP was present in or with food if GI breast-milk of upset occurs. women who take - Monitor blood azathioprine. counts regularly; - Unknown TPMT severe hematologic status or deficient effects may require the discontinuation TPMT activity due of therapy; to the high risk of increases risk of myelosuppression. neoplasia. - Known malignancy. - Clinically active infection.
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