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  • Coagulant and Anticoagulant Med Chem

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    Rushikesh Dhage
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    Vitamin K is a fat soluble vitamin that acts as a cofactor for blood clotting factors like prothrombin. It exists in different forms, with phylloquinone (K1) being the major dietary form and menaquinones (K2) being produced by bacteria. Vitamin K antagonists like warfarin work by interfering with the vitamin K cycle and inhibiting the regeneration of vitamin K from its oxidized form, leading to reduced clotting factor production.

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    Vitamin K is a fat soluble vitamin that acts as a cofactor for blood clotting factors like prothrombin. It exists in different forms, with phylloquinone (K1) being the major dietary form and menaquinones (K2) being produced by bacteria. Vitamin K antagonists like warfarin work by interfering with the vitamin K cycle and inhibiting the regeneration of vitamin K from its oxidized form, leading to reduced clotting factor production.

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    © All Rights Reserved
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    8 views5 pages

    Coagulant and Anticoagulant Med Chem

    Uploaded by

    Rushikesh Dhage
    Vitamin K is a fat soluble vitamin that acts as a cofactor for blood clotting factors like prothrombin. It exists in different forms, with phylloquinone (K1) being the major dietary form and menaquinones (K2) being produced by bacteria. Vitamin K antagonists like warfarin work by interfering with the vitamin K cycle and inhibiting the regeneration of vitamin K from its oxidized form, leading to reduced clotting factor production.

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    of 5

    COAGU(ANTS

    Cogqulan
    that causy coagutaton og blol
    ac indicaten h ae mooohoyt
    Condition
    ClasiFicaion:
    Nitamin k
    h : phyBona dinc

    fat Soluble s menadiou ,Acota


    menadne
    b) waR SOwbe enaiore
    Sodiur) btspte

    MOA
    " víBomi n k isis GOqurotd
    eoqutd Foo Syes
    a cloting.factoo T,

    Car bo|ohon 0chn


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    (I, YI, , )
    ut4 K
    scucocd
    Foon) (oRicdisecl Forsm)
    liSe
    " Dbstouctive Jaundio

    Poolonged fntimicroobtal terscapy


    Ovesdoag op orsa Aste Arti coagudot
    mlobsophon Syrdoone
    Anisindi
    ne EX.
    Devahve 3-1ndanedi
    Coe )
    CHa-0-CHg CH-
    Warsfa
    ni E
    Dervoive! Coumamn
    Closnticaton
    Clot
    te fnot
    but Form
    Clot tedusole do They
    not
    oocl. o
    bl ability
    techoose ceaqulan co
    Anti
    ANTICOAGU
    (ANIS
    2)Miscteeey Clopidol
    Kas MOA

    anticocgulcns proluce
    Coith Cyele
    hey inteact coth koeocuch
    enyme
    ho+
    SO that Vit ko doe
    eQcyo back to Vit IC
    These coill Iedel to deehy
    Hy evet Fosmot
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    WasFain
    Syntheis

    AG0 o-t-cng
    coOCHs
    Acicicotion

    Ben 2aacotoe
    (cH= CH COCh, )

    CH,cOCH3

    wasfaoin depleb n kHa by


    in hibthny
    eniyne
    Thu i4 leaco to t Fos mohey

    Ue9 bsed f poophylan!


    ~ahon cu fo h embol's
    tera Absi

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