Palhophyiology,

Homeostasis BP204T
L-2
Dr. Parjanya Shukla
Introductn, Rsgulaten, uth feadback, oypthgs Dr. N. P. Srgh ClaseS

Homeostsis i Hocneobtsis

Homeo + (Stasis
Sameness
» Homeostasis is dofned as a cymaonie sate of balone.
r eqilibmum in the internal envisonmnt of body.
’ Hhe Composihn of intmal envionnent is tightly
Cortolla Ainconstant state is called HomeDssis.
) eig- Hhe balonce of wter, elactoolytes Qcid-base Contat.
» Homeobtasis io des cobad as abi lity of body to control
A uate intemal condihns in sesponse to choryes
in exteynal envionnent.

> this is dlone by vains physiological pocesses

> Homeostabis neons Unchongin4 but achlly it dlescias
a dynamic, ever-chonging stuaten kept within nomm
imits
’ factoss msponsibla dor chomges in intumal eniomant
which re Cominuously malntains i-
D boater eleatyte Goncartaton
pt of Bodly ftuids (Tcf A&CE)
) Blood alycose levels.
 9 Oxygen Carbem dioxicla laves in blooed
tsues. Dr. Parjanya Shukla
9 Teonpeyatue af body Dr. N. P. Slngh Claoes
6) Blood pressue , Uie aud avels et:
Regulation, t Homeastasis"
’he porper Jumchonimg of body calla daperds
Pegudatem componi hen of the intersital uid
Intrstial Hid is oftn calel the intonal nvimant
» Homeostsis in body may disturbed due to changeo in
extnal evioonnt ilca hent in duwner or lack of
Oxygen duing tw0- ia un.
t abo disturbad due to chonges in ntmal envimnent
lilce incaase in B-P deeeaae in blood gucose
’ or aho istoed bystrss
psychological
ete
strses lia vooak
prsue, 2motonal By Dr fororya kr. Shakela
enelocrin Anrvs erse orrk together
YsoMeMas imdapendenty to gulate contole clstrr
-bances wasains homostvis
work
Nervws system by
Endocine syn by ’Seeetin of Hovons Csmils
>Both Meons ot gulatm, oork touys the same end,
usually trauyh 'a nagatie Josd back sysm.
 Feelback Systam' Afodback. syhom is
2ielk yes to a ies of Dr. Parjarya Shukla
eves in Lwhich the condi on of bocdy Dr. N. P. Singh ClusEs
chongeo , Ayaluatd, Monitord, evaluatel

> Any dactor uohich changs a conhollad Condiion is

known as a stimulus.

> feelback sytn incule 3 compomernts

) Recaptos Aspecial stuctue in body that monitor
chonges in a Contolleel condihm dnd
input to a Carol Cantr
b) ontl entr A Contol Canr les byain) sts the
value of Mintimia Canditons
t evaluates the input yeeived Jooon
outpu CoMmards ohen thy ae nudedlaphrss
Agenesatas

teetors cutput
Amy ogon or becy stmetue chich secived
toM the lonto! canter Aplwe
ponse
> Hiis tet althrs the controllad condihep,

(Stmulus Tes or es in Contled Conditen Acivedes

B, Dr ogorya kr- Shaukla Reaptovs)
outpu Combol
(entey Înput
HomeostMs
Maltinns. Pig Feaclbaek Systhm
 fed bock Ayotam is ane of too type ! Dr. Parjanga Shukla
&
1 Negative feedback yoten (machyison)! Dr. M. P. Singh Cla8seS

In which the efetor Simuus

spons Vso ¡¡ mgefes (egDes in Heastate, blond
the effect af oginal shimulus Volume, oY blood vessels
Mauntining Homeostupis is Comsti chen
callocd ragatve Jeed bok Tes in blod pressine

f hermones, kasgulatin ol |Chessue SensitvR ols'n

bloed luwse ete blood vesses).
Lrpu
Nes in efectors output Cortol catr
Bleodl esuoe |ertBv dilasono (Boain)
Blood vissalo

2-Posi hve jeelback aypm(Mechmis)!

’ In ohjch theector esponse. Shmuus
insases r sengthers the
fet af orgnal stmuw Jorcing the baby to endx
Moutaing the homuostusis iokla
Positve deedback syhe
» hample: Novmal chilalbirth
B, Dr loryomya kr. Shy la) Recaptors
Blond cotng in ingury, Munstal eyde Stech sensibie heyvecall
in Cerrvix)
Shancee Imput
|Sheching at utein
Control Cantr
Covix Musce) Brain)
jgtocinSahon