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5) What is the name of the molecule that results from the removal of two phosphates from ATP?
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A) adenosine diphosphate (ADP)
B) adenosine monophosphate (AMP)
C) nicotinamide adenine dinucleotide (NAD)
D) flavin adenine dinucleotide (FAD)
Answer: B
Diff: 1
Skill: Remembering
Section: Why Is Metabolism Essential to Life?
Learning Outcome: 7.1
8) Which of the following may help bind the different parts of an enzyme together to speed up a
metabolic reaction?
A) calorimeter
B) lactate
C) ketone
D) cofactor
Answer: D
Diff: 2
Skill: Understanding
Section: What Chemical Reactions Are Fundamental to Metabolism?
Learning Outcome: 7.2
9) Adenosine triphosphate (ATP) can be synthesized from adenosine monophosphate (AMP) and
adenosine diphosphate (ADP) through the process of
A) phosphorylation.
B) dephosphorylation.
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C) hydrolysis.
D) deamination.
Answer: A
Diff: 1
Skill: Remembering
Section: What Chemical Reactions Are Fundamental to Metabolism?
Learning Outcome: 7.2
16) The oxidation-reduction reactions that produce energy require which of the following
coenzymes?
A) vitamin C
B) B-vitamins
C) minerals
D) fat-soluble vitamins
Answer: B
Diff: 2
Skill: Understanding
Section: What Chemical Reactions Are Fundamental to Metabolism?
Learning Outcome: 7.2
17) What are the three end products of the oxidation-reduction reactions involved in
metabolism?
A) glucose, pyruvate, and adenosine diphosphate (ADP)
B) sucrose, lactate, and adenosine monophosphate (AMP)
C) acetyl CoA, nitrogen, and flavin adenine dinucleotide (FAD)
D) water, carbon dioxide, and ATP
Answer: D
Diff: 1
Skill: Remembering
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Section: What Chemical Reactions Are Fundamental to Metabolism?
Learning Outcome: 7.2
20) The final stage of glucose oxidation, which is carried out in the inner membranes of the
mitochondria, involves which series of reactions?
A) oxidation-reduction
B) tricarboxylic acid (TCA) cycle
C) electron transport chain
D) beta-oxidation
Answer: C
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
21) The final stage of glucose oxidation, oxidative phosphorylation, ultimately yields
A) carbon dioxide.
B) hydrogen and carbon.
C) ATP and water.
D) glucose.
Answer: C
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
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22) The first step of glycolysis is
A) deamination of glucose.
B) dephosphorylation of glucose.
C) phosphorylation of glucose.
D) condensation of glucose to lactate.
Answer: C
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
26) Which of the following cells rely on anaerobic metabolism for adenosine triphosphate (ATP)
production?
A) liver cells
B) epidermal cells
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C) red blood cells
D) neurons
Answer: C
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
27) How many ATP are produced in anaerobic glycolysis from one pyruvate molecule?
A) 0
B) 1
C) 2
D) 3
Answer: A
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
29) Which molecule is common to the metabolism of carbohydrates, fatty acids, amino acids,
and alcohol?
A) phosphofructokinase
B) hexokinase
C) carnitine
D) acetyl CoA
Answer: D
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
30) The tricarboxylic acid (TCA) cycle is a continuous loop of how many metabolic reactions?
A) 4
B) 8
C) 11
D) 21
Answer: B
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Diff: 1
Skill: Remembering
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
31) At the beginning of the tricarboxylic acid (TCA) cycle, oxaloacetate is converted into which
of the following molecules?
A) pyruvate
B) citrate
C) ATP
D) carbon dioxide
Answer: B
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
32) Which of the following metabolic pathways occurs in the cytosol of the cell?
A) glycolysis
B) TCA
C) electron transport chain
D) beta-oxidation
Answer: A
Diff: 1
Skill: Remembering
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
34) Which of the following enzymes facilitates the release of fatty acids into the blood?
A) hormone-sensitive lipase
B) hexokinase
C) pepsin
D) peptidase
Answer: A
Diff: 1
Skill: Remembering
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Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
35) Which of the following situations will result in a buildup of ketones in the blood?
A) low carbohydrate availability
B) low levels of acetyl CoA due to increased fat mobilization
C) excess of tricarboxyl acid (TCA)-cycle intermediates
D) high-carbohydrate diet
Answer: A
Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
38) In order to be used to produce energy for the body, protein—unlike carbohydrates and
lipids—must first be stripped of
A) carbon.
B) nitrogen.
C) hydrogen.
D) oxygen.
Answer: B
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted from Proteins?
Learning Outcome: 7.5
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39) Dirk is a bodybuilder. His daily intakes of carbohydrate and fat meet his body needs, but his
daily protein intake is about twice his body needs. Dirk’s excess protein intake is
A) being excreted from his body in urine in the form of urea.
B) being used for gluconeogenesis..
C) contributing to an increase in his body’s synthesis of muscle mass.
D) contributing to an increase in his body’s synthesis of fatty acids..
Answer: D
Diff: 3
Skill: Applying
Section: How Is Energy Extracted from Proteins?
Learning Outcome: 7.5
40) During protein catabolism, the body is protected against ammonia toxicity because the
A) blood transport protein albumin carries ammonia to the lungs, where it is exhaled.
B) blood transport protein albumin carries ammonia to working cells, which can catabolize it for
energy.
C) liver combines ammonia with carbon dioxide to form urea.
D) kidneys excrete ammonia from the bloodstream in urine.
Answer: C
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted from Proteins?
Learning Outcome: 7.5
42) For a person who chronically abuses alcohol, which alternative pathway becomes important
in metabolizing it?
A) microsomal ethanol oxidizing system (MEOS)
B) first pass
C) alcohol dehydrogenase
D) aldehyde dehydrogenase
Answer: A
Diff: 1
Skill: Remembering
Section: How Is Alcohol Metabolized?
Learning Outcome: 7.6
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43) What is the first step in the body's metabolism of alcohol in people with low to moderate
intakes?
A) Acetate is converted to acetyl CoA.
B) Alcohol dehydrogenase (ADH) produces acetaldehyde.
C) Aldehyde dehydrogenase produces acetate.
D) P450 enzymes produce acetyl CoA.
Answer: B
Diff: 4
Skill: Analyzing
Section: How Is Alcohol Metabolized?
Learning Outcome: 7.6
46) Evan is a well-nourished adult who weighs 70 kg (about 154 lb). How much energy reserve
would his body typically store in the form of glycogen?
A) 15 kg
B) 2 kg
C) .2 kg
D) .002 kg
Answer: C
Diff: 3
Skill: Applying
Section: How Is Energy Stored?
Learning Outcome: 7.7
47) Petra is an endurance athlete who has just completed the Boston Marathon. Which of the
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following foods would BEST help her replenish her glycogen stores?
A) fried chicken
B) whole-milk mozzarella
C) sirloin steak
D) spaghetti
Answer: D
Diff: 3
Skill: Applying
Section: How Is Energy Stored?
Learning Outcome: 7.7
48) When we eat more Calories than we need, the body responds by using
A) fat for energy and carbohydrates for storage as glycogen.
B) protein for energy and carbohydrates converted to body fat.
C) carbohydrates for energy and storing dietary fats as body fat.
D) ketones for energy and proteins converted to body fat.
Answer: C
Diff: 4
Skill: Analyzing
Section: How Is Energy Stored?
Learning Outcome: 7.7
50) As we sleep, the body maintains blood glucose levels by synthesizing glucose through
A) gluconeogenesis.
B) lipolysis.
C) proteolysis.
D) hydrolysis.
Answer: A
Diff: 2
Skill: Understanding
Section: How Are Key Nutrient Compounds Synthesized?
Learning Outcome: 7.8
51) Carbohydrates, ketogenic amino acids, and alcohol can be converted to body fat through the
process of
A) proteolysis.
B) lipogenesis.
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C) lipolysis.
D) liposuction.
Answer: B
Diff: 2
Skill: Understanding
Section: How Are Key Nutrient Compounds Synthesized?
Learning Outcome: 7.8
52) Which process plays a critical role in the synthesis of nonessential amino acids?
A) gluconeogenesis
B) transamination
C) ketosis
D) lipogenesis
Answer: B
Diff: 2
Skill: Understanding
Section: How Are Key Nutrient Compounds Synthesized?
Learning Outcome: 7.8
54) Which hormone secreted by the pancreas triggers the catabolism of glycogen?
A) glucagon
B) epinephrine
C) testosterone
D) cortisol
Answer: A
Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
55) The energy required to fight or to flee from an enemy is provided by catabolism of stored
energy prompted by which of the following hormones?
A) insulin
B) cholecystokinin (CCK)
C) ghrelin
D) cortisol
Answer: D
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Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
56) During exercise, which hormone stimulates the breakdown of stored energy?
A) insulin
B) glucagon
C) epinephrine
D) estrogen
Answer: C
Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
57) Persistent stress, coupled with a sedentary lifestyle, increases the risk for abdominal fat
accumulation and glucose intolerance because of the chronic secretion of which of the following
hormones?
A) insulin
B) glucagon
C) epinephrine
D) cortisol
Answer: D
Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
58) For people with type 2 diabetes, the cells’ ineffective response to insulin triggers
A) glycogen, triglyceride, and protein anabolism.
B) protein catabolism.
C) essential fatty acid catabolism.
D) glucose catabolism.
Answer: B
Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
59) Which metabolic pathway will predominate after eating a balanced meal?
A) lipolysis
B) gluconeogenesis
C) oxidative glycolysis
D) deamination
Answer: C
Diff: 3
Skill: Applying
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Section: How Do Feeding and Fasting Affect Metabolism?
Learning Outcome: 7.10
60) Juan ate a healthy, well-balanced meal three hours ago and is resting comfortably on the
couch. Which metabolic pathway is providing most of his ATP?
A) beta-oxidation
B) glycolysis
C) gluconeogenesis
D) lipogenesis
Answer: A
Diff: 3
Skill: Applying
Section: How Do Feeding and Fasting Affect Metabolism?
Learning Outcome: 7.10
61) After a meal has been consumed and its nutrients absorbed, what are the primary metabolic
processes occurring in the body?
A) anabolic
B) catabolic
C) gluconeogenic
D) ketonic
Answer: A
Diff: 2
Skill: Understanding
Section: How Do Feeding and Fasting Affect Metabolism?
Learning Outcome: 7.10
62) As an adverse effect of a prescription medication she was taking for acne, Violet experienced
such persistent nausea that she could not make herself eat anything for four days, after which her
physician switched her to a different medication. By the end of her fourth day of not eating, what
was Violet probably experiencing?
A) manic bursts of energy, high body temperature, and increased plasma ketone levels
B) fatigue, low body temperature, and increased plasma ketone levels
C) fatigue, fever, and an increased breakdown of glycogen stores
D) manic bursts of energy, low body temperature, and a decreased breakdown of glycogen stores
Answer: B
Diff: 3
Skill: Applying
Section: How Do Feeding and Fasting Affect Metabolism?
Learning Outcome: 7.10
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64) The process of making larger molecules from smaller ones is called anabolism.
Answer: TRUE
Diff: 1
Skill: Remembering
Section: Why Is Metabolism Essential to Life?
Learning Outcome: 7.1
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Learning Outcome: 7.3
73) Ultimately, a single 6-carbon molecule of glucose produces more ATP than a single 18-
carbon fatty acid chain.
Answer: FALSE
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
75) Amino acids produce more ATP than glucose or fatty acids can generate.
Answer: FALSE
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Proteins?
Learning Outcome: 7.5
79) The higher the intake of alcohol, the greater the activity of ethanol oxidizing enzymes.
Answer: TRUE
Diff: 2
Skill: Understanding
Section: How Is Alcohol Metabolized?
Learning Outcome: 7.6
81) The body can store an unlimited amount of excess glucose in the form of glycogen.
Answer: FALSE
Diff: 2
Skill: Understanding
Section: How Is Energy Stored?
Learning Outcome: 7.7
82) The total amount of glycogen stored in the muscle is nearly always 2 to 3 times greater than
the amount stored in the liver.
Answer: TRUE
Diff: 2
Skill: Understanding
Section: How Is Energy Stored?
Learning Outcome: 7.7
84) In most people with type 2 diabetes, the pancreas fails to make sufficient insulin.
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Answer: FALSE
Diff: 2
Skill: Understanding
Section: What Hormones Regulate Metabolism?
Learning Outcome: 7.9
86) Describe catabolism in relation to food intake, identifying digestive end products and the
ways in which the body uses them.
Answer: Answers will vary.
Diff: 2
Skill: Understanding
Section: Why Is Metabolism Essential to Life?
Learning Outcome: 7.1
87) Describe and define ATP. Why is it called the energy currency of the cell? Give specific
examples of the catabolic reactions that produce ATP.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: Why Is Metabolism Essential to Life?
Learning Outcome: 7.1
88) Distinguish between enzymes, cofactors, and coenzymes. Which is FAD? Glucokinase?
Zinc?
Answer: Answers will vary.
Diff: 2
Skill: Understanding
Section: What Chemical Reactions Are Fundamental to Metabolism?
Learning Outcome: 7.2
89) Explain the importance of nicotinamide adenine dinucleotide (NAD) and flavin adenine
dinucleotide (FAD) in oxidative metabolism.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Carbohydrates?
Learning Outcome: 7.3
90) Explain how a low-carbohydrate diet affects the rate of the TCA.
Answer: Answers will vary.
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Diff: 2
Skill: Understanding
Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
91) Explain why ketoacidosis is a significant risk in a person with type 1 diabetes who is unable
to obtain insulin.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
92) Explain why triglycerides are the most useful form of stored energy.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Fats?
Learning Outcome: 7.4
93) Distinguish between glucogenic and ketogenic amino acids, discussing the fate of their
carbon skeletons, and giving two examples of each.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: How Is Energy Extracted From Proteins?
Learning Outcome: 7.5
94) Discuss the two primary metabolic pathways for alcohol. Where are the primary sites of
alcohol metabolism? What effect do gender and age have on a person's ability to metabolize
alcohol? Why do some populations have difficulty metabolizing alcohol?
Answer: Answers will vary.
Diff: 5
Skill: Evaluating
Section: How Is Alcohol Metabolized?
Learning Outcome: 7.6
95) Describe the process by which the body synthesizes non-essential amino acids.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
Section: How Are Key Nutrient Compounds Synthesized?
Learning Outcome: 7.8
96) Discuss the metabolic shifts that occur during short-term and long-term fasting.
Answer: Answers will vary.
Diff: 4
Skill: Analyzing
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Section: How Do Feeding and Fasting Affect Metabolism?
Learning Outcome: 7.10
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Another random document with
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be allowed that such a confession as the following would be felt as
an irritant:
II
I do not wish to make a third with Pontius Pilate and Mr.
Chadband in raising the question, “What is Truth?” but merely to
suggest here that, as soon as ever you raise it over poetry or over
prose fiction, it becomes—as Aristotle did not miss to discover—
highly philosophical and ticklish. To begin at plumb bottom with your
mere matter-of-fact man, you will be asked to explain how in the
world there can be “truth” in “fiction,” the two being opponent and
mutually exclusive terms; and such a man will tell you that larkspurs
don’t listen, lilies don’t whisper, and no spray blossoms with pleasure
because a bird has clung to it; wherefore, what is the use of
pretending any such lies? Ascending a little higher in the scale of
creation, we come to another bottom, a false bottom, a Bully Bottom,
who enjoys make-believe, but feels it will never do “to bring in (God
shield us!) a lion among ladies.” Still ascending past much timber, we
emerge on the decks of argosies—
Like signiors and rich burghers on the flood,
portlily negligent of all this bottom-business on which they ride,
carrying piled canvas over the foam of perilous seas. In short, the
man who hasn’t it in his soul that there is a truth of emotion and a
truth of imagination just as solid for a keelson as any truth of fact,
merely does not know what literature is about. As Heine once said of
a fat opponent, “it is easier for a camel to enter the Kingdom of
Heaven than for that fellow to pass through the eye of a needle.”
Now Trollope, if we look at him in one way, and consider him as an
entirely honest Bottom, simply saw Micawber as a grotesque
creation and Victor Hugo as a writer extravagantly untrue to nature.
He merely could not understand what Hugo would be aiming at (say)
in Gastibelza or in the divine serenade:
Here Trollope asserts less than one-half of his true claim. He not
only carried all Barsetshire in his brain as a map, with every cross-
road, by-lane, and footpath noted—Trollope was great at cross-
roads, having as an official reorganised, simplified, and speeded-up
the postal service over a great part of rural England—but knew all
the country-houses, small or great, of that shire, with their families,
pedigrees, intermarriages, political interests, monetary anxieties, the
rise and fall of interdependent squires, parsons, tenants; how a
mortgage, for example, will influence a character, a bank-book set
going a matrimonial intrigue, a transferred bill operate on a man’s
sense of honour. You seem to see him moving about the Cathedral
Close in “very serviceable suit of black,” or passing the gates and
lodge of a grand house in old hunting-pink like a very wise solicitor
on a holiday: garrulous, to be sure, but to be trusted with any secret
—to be trusted most of all, perhaps, with that secret of a maiden’s
love which as yet she hardly dares to avow to herself. Here let us
listen to the late Frederic Harrison, who puts it exactly:
8
I should prefer to say that it grew.—Q.