TRANSCRIPTION, TRANSLATION AND MUTATION ACTIVITY

For each example:

a. Fill in the complimentary DNA strand
b. Fill in the correct mRNA bases by transcribing the bottom DNA code
c. Fill in the correct tRNA bases
d. Translate the mRNA codons to find the correct amino acids

Example 1. Assume TAC-CGT-AAT-ACT sequence in the DNA template strand

DNA Coding
Strand

DNA Template
Strand

mRNA
(codon strand)

tRNA
(anticodon codon)

Amino Acids

Example 2. The 7th base becomes G replacing A? (TAC-CGT-GAT-ACT)

DNA Coding
Strand

DNA Template
Strand

mRNA

tRNA
Amino Acids
Example 3. The 8th base becomes T replacing A? (TAC-CGT-ATT-ACT)

DNA Coding
Strand

DNA Template
Strand

mRNA

tRNA
Amino Acids

Example 4. The 7th base becomes C replacing A? (TAC-CGT-CAT-ACT)

DNA Coding
Strand

DNA Template
Strand

mRNA

tRNA
Amino Acids
Example 5. What if A is added in the 4th position? (TAC-ACG-TAA-TAC)

DNA Coding
Strand

DNA Template
Strand

mRNA

tRNA
Amino Acids

Example 6. How about removing G in the 5th position? (TAC-CTA-ATA-CTC)

DNA Coding
Strand

DNA Template
Strand

mRNA

tRNA
Amino Acids

What do you notice? What do you wonder?

-dmgermino’2023
CODON CHART