7.

Management options for solar urticaria include all of the following

except:

a. antihistamines

b. phototherapy

c. sunscreen

d. polypodium leucotome extract*

e. psoralen plus UVA phototherapy

16. Which T-cell subset is commonly found in Sezary syndrome?

a. CD4+/CD7+

b. CD8+/CD7-

C. CD4-/CD7+

d. CD4+/CD7- *

e. CD8+/CD7+

19. The main cytokine secreted by Th1 CD8+ effector T-cells is:

a. IL-1

b. IL-2

c.IFN-gamma *

d.IL-4

e. IL-5

21. This skin disease has been shown to be associated with reduced
Beta 2 defensin. The diagnosis is:

a. Atopic dermatitis*

b. Psoriasis
c. Lepromatous leprosy

d. Tuberculoid leprosy

e. Subacute cutaneous lupus erythematosus

22. Langerhans cell adhesion to keratinocytes is mediated by what

adhesion molecule?

a. E-cadherin*

b. N-cadherin

c. Desmoglein 3

d. P-cadherin

e.B7

33. Which of the following cytokines are secreted from keratinocytes?

a. IL-2

b.IL-3

c.IL-17

d.IL-22

e.IL-23*

36. The formation of granulation tissue depends on the presence of:

a. Neutrophils

b.Fibronectin *

C.Collagen type I

d.Platelets
 e.Collagen type IV

52. Which of the following dermal cells always express CD11c and
CD6?

a. Mononuclear phagocytic cells*

b. Fibroblasts

c. Mast cells

d. Erythrocytes

e. Glomus cells

e. Dermatomyositis

15- IgE is produced by

a- Helper T cells

b- Suppressor T cells

c- Mast cells

d- B cells

e- Esinophile cells

61. Which of the following disorders is primarily associated with a

monoclonal gammopathy of the IgA type?

a. Scleromyxedema

b. Scleredema

c. Necrobiotic xanthogranuloma

d. Schnitzler's syndrome

e. Pyoderma gangrenosusm*

7- which of the following is the most common physical Urticaria:-

a- Cholinergic
b- Dermatographism
c- Acquagenic
d- Pressure
e- Cold Urticaria

23. Proteins in the alternate complement pathway include:

f- a. Factor B
g- b.properdin
h- c. C3
i- d. Factor B and properdin
j- e .Factor B, properdin and C3*

18. Active immunizations is induced by the administration of all of

the following except

a- Bacterial products

b- toxoids*

c- Vaccines

d- Antitoxins

e- Attenuated pathogens

19. The radioimmunosorbent test (RIST) is a technique used to

measure

a- Cellular antigens

b- Both antigen and antibody activity

c- Allergins in food
 d- Specific IgE levels*

e- Total IgE concentration

32-Regarding cytokines all the following statements are true except:-

a)IL-4 stimulates B-lymphocyte proliferation.

b)IFN-alpha produced by macrophage.

c)TGF-beta stimulates wound healing.

d)TNF-alpha induces prostaglandin synthesis.

e)TNF-beta is elevated in UV radiation.

1. The immunologic effects of UVR include all of the following

except:
Alteration of Langerhans cell morphology a
Decrease in IL-1, IL-6, TNF-alpha b
Suppression of delayed-type hypersensitivity c
Alteration of lymphocyte population d
Alteration of Langerhans cell function e

27. In solar urticaria wheals may be brought on by:

UVA a
UVB b
UVC c
Visible light d
UVA, UVB and Visible light e
51. Which of the following cell types induce susceptibility to tumor
growth?
Suppressor T-cells a
NK cells b
Helper T-cells c
Mast cells d
Langerhans cells
e
 53. As a result of ultraviolet radiation:
There is mast cell degranulation and release of histamine a
Prostaglandins are increased b
Epidermal thickening occurs c
All of these answers are correct d
None of these answers are correct e

110. The following compound exerts immunosuppressive effects

in the skin following exposure to UV-radiation:
Cis-urocanic acid a
7-dehydrocholesterol b
IL-12 c
Delta aminolevulinic acid d
Amino-levulinic acid e