XENA MAXINE A, CASTRO

BSN 2 BLK 5

ENDO

EMFAGLIPOZIN ACTION/ INDICATON CONTRAINDICATION ADVERSE SIDE NURSING

PHARMACODYNAMICS EFFECT EFFECT CONSIDERATION
THERAPEUTIC Selective sodium- Empagliflozin is . Empagliflozin is -low blood -dehydration
CLASS: glucose transporter-2 a medication contraindicated for pressure -dizziness Before initiating
Antidiabetics (SGLT2) inhibitor used to severe renal (hypotension) - JARDIANCE,
improve impairment, GFR -increased lightheadedness assess volume
PHAMACOLOGIC SGLT2 is expressed in glycemic less than 30 thirst -weakness, status and renal
CLASS: the proximal renal control in type mL/min/1.73m^2, -frequent -yeast infection function
SGLT-2 inhibitors tubules and is 2 diabetes during pregnancy, urination -low blood sugar
responsible for the patients, end-stage renal -nausea -nausea In patients with
majority of the reduce the risk disease, dialysis, -vomiting -upper volume
AVAILABLE reabsorption of filtered of severe -weakness respiratory tract depletion,
FORM: glucose from the cardiovascular hypersensitivity -fatigue infection correct this
tablet tubular lumen; SGLT2 death in adults reactions, hepatic -shortness of -high cholesterol condition before
10mg inhibitors reduce with both type impairment, and breath -joint pain initiating
25mg glucose reabsorption 2 diabetes and Type 1 diabetes or -fruity breath -increased JARDIANCE
and lower the renal established diabetic odor urination
BRAND NAME: threshold for glucose, cardiovascular ketoacidosis. -confusion -urinary tract Monitor for signs
Glyxambi, thereby increasing disease, and -little or no infection and symptoms of
Jardiance, urinary glucose reduce the risk urination -thirst volume
Synjardy, Trijardy excretion of heart failure -swelling in -low blood depletion, and
and end-stage legs and ankles pressure renal function
Also reduces sodium kidney disease. -convulsions (hypotension). after initiating
reabsorption and It is not (seizures) therapy.
increases the delivery approved for -chest pain or
of sodium to the distal use in patients pressure
tubule; this may with type 1 -decreased
influence several diabetes. An urination
physiological functions, extended-
such as lowering both release -irregular
pre-and afterload of combination heartbeat
the heart and product -fever
downregulating containing -pain in the
sympathetic activity empagliflozin, lower sides of
metformin, and your back
linagliptin was -extreme
approved by tiredness
the FDA in -chills
January 2020. -cloudy, dark,
bloody or foul-
smelling urine
-frequent and
painful
urination
-pale skin
-shakiness
-anxiety
-sweating
-hunger
-irritability
-pain or
swelling in the
genital area
-itching and
irritation in the
genital area
-burning
sensation
during
intercourse
-vaginal pain
and soreness
 -vaginal
discharge, and
elevated levels
of LDL
cholesterol

REFFERENCES

https://www.ncbi.nlm.nih.gov/books/NBK532925/

https://go.drugbank.com/drugs/DB09038

https://reference.medscape.com/drug/jardiance-empagliflozin-999907#0