Lyceum of the Philippines University

College of Nursing

DRUG STUDY

Drug Name Classification Indication Contraindication Side Effects/Adverse Nursing Monitoring

and Mechanism Reaction Responsibilities Parameters
of Actions

Brand Name: - Calcium-channel - Severe - Transient fetal - Sweating - Monitoring vital - Blood pressure
blocker hypertension or heart rate signs closely, (continuously for IV
Cardene IV (dihydropyridine) or hypertensive decelerations and - Tiredness including blood infusion)
ion antagonist
emergencies neonatal pressure and fetal
indicated for the - Coldness
short-term (preeclampsia, hypotension and heart rate.
treatment of eclampsia) in acidosis (pH less - Little or no urine - heart rate, liver
hypertension when preventing maternal than 7.25) and kidney function
Generic Name: oral therapy is not and fetal - Pain and tenderness
- Assessing for
feasible or not complications such
Nicardipine IV desirable. - Loss of appetite signs of
as stroke, placental - Hypersensitivity to hypotension in
abruption, or fetal - infusion site for
(Nicardipine - Has nicardipine or other - Mood Changes both the mother
distress. extravasation
Hydrochloride) antihypertensive calcium-channel and fetus.
- Muscle pain or cramps
properties and is blockers.
effective in the
- Fast pounding, irregular
treatment of angina - uterine activity
Dosage: - Chronic and heartbeat
and coronary - Providing
spasms without gestational continuous fetal
Capsule showing cardio hypertension - Slurred speech
monitoring during
depressant effects. - Fluid intake and
- 20 mg - Hypotension administration. output
- produce relaxation
- 30 mg of coronary vascular - Pre term labor - Fetal distress
smooth muscle at associated with
drug levels that uterine contractions - Potential harm to fetus - Educating the - Maternal heart rate
cause little or no patient about the
Infusion Solution negative inotropic potential risk and
effect. benefits of
- 20 mg/200ml - Renal diseases - Signs of adverse
Nicardipine. reactions
- 40 mg/200ml
- Reporting any
adverse reactions
or changes in the - Maternal well-
Injectable Solution patient’s condition being
to the healthcare
- 2.5 mg/ml
provider promptly.

Route:

- thru IV infusion

(continuous infusion)

- Oral Intake

Frequency:

- q8hr

(conventional)
- q12hr

(extended – Release)