Understanding the Difference Between Systematic and Integrative Literature Review

Writing a literature review can be a daunting task, especially when you're faced with the challenge of
differentiating between systematic and integrative approaches. It requires thorough research, critical
analysis, and the ability to synthesize information from various sources. Many students and
researchers struggle with this aspect of academic writing, often finding themselves overwhelmed by
the sheer volume of literature available and unsure of how to structure their review effectively.

One of the main difficulties in writing a literature review is knowing where to start. With so much
information out there, it can be challenging to narrow down your focus and identify the most
relevant studies for your topic. Additionally, distinguishing between systematic and integrative
literature reviews requires a clear understanding of the differences between the two approaches.

A systematic literature review involves a methodical and comprehensive search of existing literature
on a particular topic. It aims to identify, evaluate, and synthesize all relevant studies using predefined
criteria and rigorous methodology. This type of review follows a structured approach, often including
specific steps such as defining research questions, conducting a thorough search of databases,
screening articles for inclusion, and assessing the quality of the included studies.

On the other hand, an integrative literature review focuses on synthesizing findings from a broad
range of sources to provide a comprehensive overview of a topic. Unlike systematic reviews,
integrative reviews do not adhere to strict inclusion criteria or predefined methodology. Instead, they
aim to explore diverse perspectives, theories, and approaches within the literature to develop a more
holistic understanding of the subject matter.

Both systematic and integrative literature reviews have their advantages and limitations, and the
choice between them depends on the research question, objectives, and scope of the review. While
systematic reviews are valued for their methodological rigor and ability to provide robust evidence,
integrative reviews offer flexibility and allow for a broader exploration of concepts and theories.

In conclusion, writing a literature review can be a challenging but rewarding endeavor. It requires
careful planning, critical thinking, and attention to detail. If you find yourself struggling with this
task, consider seeking assistance from professional academic writers. ⇒ StudyHub.vip ⇔ offers
expert guidance and support to help you navigate the complexities of literature review writing. With
our experienced team of writers, you can rest assured that your review will be meticulously crafted
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Although meta-analysis can increase the precision of a result, it is important to ensure that the
methods used for the reviews were valid and reliable. Consider the following issues before writing
the literature review: Clarify If your assignment is not specific about what form your literature
review should take, seek clarification from your professor by asking these questions: 1. Data
availability The data supporting the conclusions of this manuscript will be made available by the
corresponding authors on a reasonable request. One such tool that a novice nurse may employ is the
Peer Review of the Search Strategy (PRESS) checklist. North Am J Med Sci. 2011;4(1) World
Health Organization. Note: You must create a free account to search EvidenceAlerts. The retrieved
studies are then screened for eligibility using the inclusion and exclusion criteria (this is done by at
least two people working independently). This is called citation tracking and there are a number of
sources that can help you identify who has cited whom, particularly scholars from outside of your
discipline. The second most frequent site was lower limbs (femur or fibula or tibia), identified in 35
patients (33%), 23 males (65.7%) and 12 females (34.3%), in particular, proximal femur was involved
in 17 cases. Further research may consider other factors that may explain the source of high
heterogeneity among studies on HBV prevalence in China. Systematic reviews and meta-analyses
usually proceed according to the flowchart presented in Fig. 2. We explain each of the stages below.
Searching for grey literature for systematic reviews: challenges and benefits. An annotated
bibliography is a list of source references that has a short description (called an annotation ) for each
of the sources. A literature review is a survey of scholarly sources on a specific topic. Cornell
University Systematic Review Decision Tree This decision tree is designed to assist researchers in
choosing a review type. Eighty-five papers (65 papers in PubMed and 20 papers in Embase) were
retrieved. More Information: Comparing Integrative and Systematic Literature Reviews Almost half
of literature reviews submitted are integrative lit-erature reviews, whereas the other half are
composed of systematic literature reviews (12.5%), and others (e.g., structured literature reviews),
while the remaining (29%) did not use any particular review method. Many studies are registered
with an organization like PROSPERO ( ), and the registration number is recorded when reporting the
study, in order to share the protocol at the time of planning. For more about this topic, check out
Systematic Review VS Meta-Analysis article. Case of renin-producing Juxtaglomerular Tumor:
effect of ACE inhibitor or angiotensin II receptor antagonist. Clinical, surgical, and histological
features About the site of malignant degeneration, axial skeleton was involved in 57% of cases. The
Writing Center. University of North Carolina; Onwuegbuzie, Anthony J. Aveyard and Bradbury-
Jones (2019) suggested that integrative reviews exhibit similar characteristics to systematic reviews
and may therefore be regarded as rigorous. From January 2005 to July 2020, fifteen patients
diagnosed as JGCT by surgical pathology in Peking Union Medical College Hospital were collected.
A comparison of the performance of seven key bibliographic databases in identifying all relevant
systematic reviews of interventions for hypertension. Syst Rev. 2016;5(1):27. The National Library
of Medicine. Even if the median age is in line with medical literature, the present series highlighted
the presence of younger patient affected by secondary peripheral chondrosarcoma, particularly
because some of these cases are grade 2 SPC. Even when the data cannot be shown to be
homogeneous, a fixed-effect model can be used, ignoring the heterogeneity, and all the study results
can be presented individually, without combining them. The main reason is that the observational
studies may entail an increased risk of biases and high levels of heterogeneity. The risk of antenatal
parasitemia is 286 events per every 1,000 people. Factors associated to a worse course of the disease
were histological grade 2 and 3, and partial resection surgery.
The search should be documented as it occurs and changes noted and justified. If it is determined
that the different research outcomes cannot be combined, all the results and characteristics of the
individual studies are displayed in a table or in a descriptive form; this is referred to as a qualitative
review. For instance, the systematic review will include: Eligibility criteria for included research A
description of the systematic research search strategy An assessment of the validity of reviewed
research Interpretations of the results of research included in the review As you can see, contrary to
the general overview or summary of a topic, the systematic literature review includes much more
detail and work to compile than a standard literature review. The components of a literature review,
for example, are similar to any other research paper. As our understanding of evidence-based
medicine increases and its importance is better appreciated, the number of systematic reviews and
meta-analyses will keep increasing. Little guidance is available on how to write an integrative
literature review. Analysis on economic efficacy regarding previous strategies and current
recommendations for vaccination against hepatitis B virus in China. However, we strongly advise
against trying to pass AI-generated text off as your own work. Systematic reviews include
experimental studies, and many times only randomized controlled trials. Guidance Notes for
Registering A Systematic Review Protocol with PROSPERO OSF Registries Open Science
Framework (OSF) Registries is an open network of study registgrations and pre-registrations.
Understanding and Evaluating Systematic Reviews and Meta-analyses A systematic review is a
summary of existing evidence that answers a specific clinical question, contains a thorough,
unbiased search of the relevant literature, explicit criteria for assessing studies and structured
presentation of the results. This article discusses how to organize and write an integrative literature
review and cites examples of published integrative literature reviews. Because of this, when carried
out well, they provide reliable estimates about the effects of interventions so that conclusions are
defensible. This example shows a specific type of effect size: relative risk. A systematic review that
incorporates quantitative pooling of similar studies to produce an overall. Meta-Analysis, Systematic,
and Integrative Reviews: An Overview Highlights. Primary care physicians need evidence for both
clinical practice and for public health decision making. Socioeconomic inequality in hepatitis B
vaccination of rural adults in China. You can find critically-appraised individual articles in these
resources: EvidenceAlerts Quality articles from over 120 clinical journals are selected by research
staff and then rated for clinical relevance and interest by an international group of physicians. A
patient had a malignant transformation of calcaneal region OC and another patient at clavicle (Tables
2 and 3 ). The data is also analyzed for heterogeneity (variation within outcomes), and
generalizability (similarities between outcomes) within the individual studies, which facilitates more
effective clinical decision making. Download citation Received: 18 April 2023 Accepted: 05
February 2024 Published: 16 February 2024 DOI: Share this article Anyone you share the following
link with will be able to read this content: Sorry, a shareable link is not currently available for this
article. A meta-regression analysis is similar to a normal regression analysis, except that the
heterogeneity between studies is modeled. Filtered Resources: Critically-Appraised Topics Critically-
appraised individual articles Authors of critically-appraised individual articles evaluate and synopsize
individual research studies. Our objective is to use explicit, systematic, and transparent methods to
develop an evidence-based and agreement-based reporting guideline for overviews of reviews of
healthcare interventions (PRIOR, Preferred Reporting Items for Overviews of Reviews). Thus, a
systematic review is where you might find the most relevant, adequate, and current information
regarding a specific topic. Or several studies on the effects of a treatment might come to different
conclusions. This article discusses how to organize and write an integrative literature review and
cites examples of published integrative literature reviews. BMJ Glob Health. 2020;5(6). Zhang SX,
Dang RB, Zhang WD, Liang XF, Cui FQ. Independent-samples T test or Fisher’s exact test was used
to compare the differences between the two groups.
Types of literature reviews: summaries of relevant literature generally descriptive not necessarily any
analysis of the literature methodology of the literature search is not always given good for gaining
background knowledge of a subject without having to do all the searches and reading yourself.
Understanding and Evaluating Systematic Reviews and Meta-analyses A systematic review is a
summary of existing evidence that answers a specific clinical question, contains a thorough,
unbiased search of the relevant literature, explicit criteria for assessing studies and structured
presentation of the results. Federal government websites often end in.gov or.mil. Before sharing
sensitive information, make sure you’re on a federal government site. However, heterogeneity in the
subgroup analysis did not decrease substantially. The 7 steps for conducting a systematic review are
explained with an example. This page describes rapid reviews, including their limitations, alternate
names, and how they differ from traditional systematic reviews. Supplementary Information
Additional file 1.. Search Term Additional file 2: Table S1. When combining data for dichotomous
variables, the OR, risk ratio (RR), or risk difference (RD) can be used. The prevalence of hepatitis B
in Chinese general population from 2018 Systematic searches of literature from January 1, 2018 to
December 25, 2022 were conducted in four international databases (Medline, Web of Science,
Embase, Cochrane Database of Systematic Reviews) and three Chinese databases (CNKI, CBM, and
WanFang data).. We performed an updated systematic review and meta-analysis to identify new
studies. Reprints and permissions About this article Cite this article. Gnoli, M., Gambarotti, M.,
Righi, A. et al. Secondary peripheral chondrosarcoma in multiple osteochondromas: a retrospective
single-institution case series. Dynamic contrast-enhanced CT showed nine mild enhancement, and
two moderate enhancement in parenchymal phase. Systematic reviews are suitable for biomedical
and healthcare studies, but they can also be used in other areas that require an evaluation of a
specifically defined subject. It is therefore an approach for systematically combining pertinent
qualitative and quantitative study data from several included studies to establish a single conclusion
that has significant statistical power. They compare and contrast 14 review types, listing the strengths
and weaknesses of each review. Veronica Tanco Tellechea Leave a reply cancel reply. It is a
comprehensive, transparent search that can be replicated and reproduced by other researchers. When
combining data from continuous variables, the mean difference (MD) and standardized mean
difference (SMD) are used ( Table 2 ). Outcome in disease-free survival highlights that a worse
course of the disease was associated with histological grade 2 or 3, and partial resection surgery. The
Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this
article, unless otherwise stated in a credit line to the data. Because ultrasound and non-enhanced CT
can fail, contrast enhanced CT should be performed when a JGCT is suspected. This type of review
involves formulating research questions (broad or focused in scope) and then identifying and
synthesizing information related to the research questions. Scoping reviews serve to synthesize
evidence and assess the scope of literature on a topic. Another strategy is to scan the reference lists
of relevant studies. The overall aim and mission of the Primary Health Care Field is to promote the
quality, quantity, dissemination, accessibility, applicability, and impact of Cochrane systematic
reviews relevant to people who work in primary care and to ensure proper representation in the
interests of primary care clinicians and consumers in Cochrane reviews and review groups, and in
other entities. The patents indexed help find results of research not otherwise publicly available
because it has been done for commercial purposes. We searched MEDLINE, Google Scholar and the
Cochrane Library. When writing your review, keep in mind these issues. The bibliography or
reference section of sources you've already read, such as required readings in the course syllabus, are
also excellent entry points into your own research. If there’s no previous research, there’s nothing to
review. CINeMA: an approach for assessing confidence in the results of a network meta-analysis.
PLoS Med. 2020;17(4):e1003082.
Which principles constitute a user-centered agile software development approach? The preoperative
CT diagnosis was three reninoma, one renal cell carcinoma, and seven undetermined tumors. Log
scale is used to combine the data to estimate the weighting. Fig. 7. Codes and number of articles
related to the artifact-mediated communication principle. In the fourth stage, the ?nal sample passed
a ?rst categorization. J Bone Joint Surg Br. 2004.. Article PubMed Google Scholar Pacifici M. This
can be especially helpful for students or scholars getting into a new research area, or for directing an
entire community of scholars toward questions that have not yet been answered. In terms of quality
assessment, all the studies (100%) had a total quality of more than 4 points, 14 (56%) studies had a
total quality of 5 points, and one article (4%) had a total quality of more than 5 points (Additional
file 4: Table S3). Context: In the last decade, software development has been characterized by two
major approaches: agile. Mutation screening of EXT1 and EXT2 by denaturing high-performance
liquid chromatography, direct sequencing analysis, fluorescence in situ hybridization, and a new
multiplex ligation-dependent probe amplification probe set in patients with multiple
osteochondromas. Synthesize the main findings of your research Report Findings Report the results
using a statistical approach or in a narrative form. Little guidance is available on how to write an
integrative literature review. By Carol Hollier on 07-Jan-2020 12:42:03 For those not immersed in
systematic reviews, understanding the difference between a systematic review and a systematic
literature review can be confusing. It is very common for PhD theses to contain some element of
reviewing the literature around a particular topic. The use of established tools to structure the various
components of an integrative review increases robustness and readers’ confidence in the review
findings. Meta-analysis might prove to be a bad choice when the answer to the review question is
better with qualitative data. Quality Appraisal Tools for Integrative Reviews Critical Appraisal Skills
Programme (CASP) Checklists Appraisal checklists designed for use with Systematic Reviews,
Randomized Controlled Trials, Cohort Studies, Case Control Studies, Economic Evaluations,
Diagnostic Studies, Qualitative studies and Clinical Prediction Rule. Using the meta-synthesis
method, she has been able to detect mixed conceptions, homonyms, and the hierarchy of concepts
that should construct these two phenomena. In this article, we will look at the definition of a
systematic review, and understand how it is different from a meta-analysis. The risk of perinatal
hepatitis B virus transmission: hepatitis B e antigen (HBeAg) prevalence estimates for all world
regions. These tools include variations on the PICOTs template (PICOT, PICO, PIO), and the Spider
template. Within healthcare, systematic literature reviews initially gained traction and widespread
support because of their reproducibility and focus on arriving at evidence-based conclusions that
could influence practice and policy development ( Boell and Cecez-Kecmanovic, 2015 ). Defining
inclusion and exclusion criteria Information is included on the study design, patient characteristics,
publication status (published or unpublished), language used, and research period. Characteristics of
age groups of the studies included in the meta-analysis Additional file 4: Table S3. You can either
browse individual issues or use the search box in the upper-right corner. Systematic review and meta-
analysis are two terms that you might see used interchangeably. Explain - The synthesized results are
articulated and contextualized. In this presented review, there were 6 studies on rural prevalence and
5 studies on urban prevalence. The most common quantitative approach is a meta-analysis, which
allows you to combine results from multiple studies into a summary result.
Integrative reviews thus by involving both experimental ad theoretical studies are able to point out
research gaps and examine systematic issues. JBI EBP Database (formerly Joanna Briggs Institute
EBP Database) To find critically-appraised topics in JBI, click on Limits and then select Evidence
Summaries from the Publication Types box. The protocol of this systematic review was registered in
the International prospective register of systematic reviews (PROSPERO), National Institute for
Health research (Number: CRD42023396671). However, systematic reviews are quite complex and
can take months, if not years, to complete. This review objective is delineated in the review question
templates shown in Table 1. It provides detailed guidelines on how to complete each step of the
systematic review process. Asking the right question: specifying your study question.
Characterization and management of Juxtaglomerular Cell Tumor: analysis of 9 cases and literature
review. HIV risk behavior and HIV testing among rural and urban men who have sex with men in
Zhejiang Province, China: A respondent-driven sampling study. PLoS One. 2020;15(4):e0231026..
Wang Y, Liu H, Zhao M, Feldman MW, Williams AB. A summary is a recap of the important
information of the source, but a synthesis is a re-organization, or a reshuffling, of that information in
a way that informs how you are planning to investigate a research problem. Outcomes from a meta-
analysis may provide more precise information regarding the estimate of the effect of what is being
studied because it merges outcomes from multiple studies. Bias is a topic we will come to in a later
chapter, but for now you can think of bias as anything that systematically takes us away from the
“truth”. Use PRISMA-ScR, a 20-item checklist, for reporting scoping reviews. Clin Orthop Relat
Res. 2015.. Kivioja A, Ervasti H, Kinnunen J, Kaitila I, Wolf M, Bohling T. This information is often
presented graphically in a flow diagram like this one from Radeva-Petrova et al. ( 2014 ). Federal
government websites often end in.gov or.mil. Before sharing sensitive information, make sure you’re
on a federal government site. For instance, the intervention may work differently in different
contexts, and the included studies were gathered from all over the world. Write what is already
known about the topic and what do the sources that you have reviewed say. Codes related to the
parallel interwoven creation tracks principle. She had the main role in revising process for the final
draft. Research objective (s): Rephrase your research question as an objective. An integrative review
helps to develop a comprehensive understanding of the topic by synthesizing all forms of available
evidence (Dhollande et al., 2021). They allow healthcare professionals to use all available evidence
from both qualitative and quantitative research to provide a more holistic understanding of the topic,
which can then be applied to clinical practice. A hepatitis B seroprevalence survey in a 0-79-year-old
healthy population of Zhengzhou city in 2020. Systematic reviews are increasingly published in
orthopedic surgery, many answering the same clinical questions with different conclusions. In such a
case, it might not make sense to attempt to determine one overall meta effect size from a comparison
of the studies. J Med Genet. 2001.. Hecht JT, Hogue D, Wang Y, Blanton SH, Wagner M, Strong
LC, Raskind W, Hansen MF, Wells D. Evaluate - In this step, retrieved articles are screened and
sorted using the predetermined inclusion and exclusion criteria. Moreover, our results show that a
worse course of the disease is associated with higher histological grade. Values greater than 75% may
indicate that a change in the meta-analysis method (random vs fixed effects) is needed. February 15,
2024 Advanced Statistical Methods in Meta-analysis: Enhancing Accuracy, Reliability, and Insights
February 12, 2024 Inventions in Medical Therapeutics: There’s a World of Possibilities February 1,
2024.
Although an ILR aims to follow similar approaches to that of a systematic review, it allows for the
inclusion of both primary research studies, along with other documents (including opinions. Every
author or researcher is required to cohere to the given standards of reporting and conducting (META-
EVIDENCE BLOG, 2018). Systematic Reviews and Meta Analysis A systematic review may
include a meta-analysis. For example, a review that examines literature supporting or refuting an
argument, assumption, or philosophical problem related to the research problem will also need to
include writing supported by sources that establish the history of these arguments in the literature.
However, study selection via a systematic review is a precondition for performing a meta-analysis,
and it is important to clearly define the Population, Intervention, Comparison, Outcomes (PICO)
parameters that are central to evidence-based research. Contains the clinical portions of Harrison's
Principles of Internal Medicine. All authors read and approved the final manuscript. JBI maintains a
page with other materials for scoping reviewers. Write the review Thompson Writing Studio This link
opens in a new window Need to write a systematic review. This is the most common form of review
in the social sciences. Ethics declarations Ethics approval and consent to participate, consent for
publication. Federal government websites often end in.gov or.mil. Before sharing sensitive
information, make sure you’re on a federal government site. Some examples of the different methods
that you can use to gather data are given below. Our meta-analysis and previous meta-analysis
identified similar prevalence of HBV in both males and females. In order to test the presence or
absence of publication bias, first, a funnel plot can be used ( Fig. 5 ). Studies are plotted on a scatter
plot with effect size on the x-axis and precision or total sample size on the y-axis. Integrative
reviews allow for the incorporation of various approaches, including experimental and non-
experimental methods of review. Systematic Reviews and Meta Analysis PRISMA-P is a 17-item
checklist for elements considered essential in protocol for a systematic review or meta-analysis.
Screening, data extraction and quality assessment Articles were screened independently by the
primary reviewer and at least one secondary reviewer, with all conflicting decisions agreed up
between reviewers. This makes it possible to test whether the effect size calculated from several
studies is the same. This blog presents the three types of heterogeneity, considers the different types
of outcome data, and delves a little more into dealing with the variations. Case study An in-depth,
detailed examination of specific cases within a real-world context. Every aspect of a systematic
literature review, including the research protocols, which databases are used, and dates of each
search, must be transparent so that other researchers can be assured that the systematic literature
review is comprehensive and focused. Were the results effectively interpreted and reported. They
also collected data about possible sources of bias, such as how the study participants were
randomized into the control and treatment groups. MT contributed to data collection and draft of the
manuscript. Clarity on the types of reviews and associated methodologies can assist in evaluating the
science of. Doing Your Literature Review: Traditional and Systematic Techniques. Inclusion and
exclusion criteria allow the novice nursing researcher to reduce and refine the search parameters and
locate the specific data they seek. This is the explanation for updates made to the manual linked
below. PROSPERO: International prospective register of systematic reviews PROSPERO is an
international database of prospectively registered systematic reviews in health and social care,
welfare, public health, education, crime, justice, and international development, where there is a
health related outcome.
In medicine, clinical trial registries are another important type of gray literature. Not applicable.
Competing interests The authors declare that they have no competing interests. It allows you to
explore the key characteristics, meanings, and implications of the case. First, the heterogeneity of
meta-analysis was high. Most lit reviews use a basic introduction-body-conclusion structure; if your
lit review is part of a larger paper, the introduction and conclusion pieces may be just a few
sentences while you focus most of your attention on the body. A manual citation search of the
reference list of all sourced papers was also undertaken by a member of the research team. Gray
literature: Gray literature includes documents produced by governments, universities, and other
institutions that aren’t published by traditional publishers. The search terms, search strategies
(including database names, platforms, dates of search) and limits all need to be included in the
review. On the other hand, a theoretical study does not use experimental or empirical evidence,
rather it involves the use of interviews, observations, or a combination of theoretical data to develop
its findings. There are various types of literature reviews based largely on the type of literature
sourced ( Cronin et al. 2008 ). These include systematic literature reviews, traditional, narrative and
integrative literature reviews ( Snyder, 2019 ). Narrative synthesis combines the findings of multiple
studies using words. J Bone Jt Surg. 2013;95(11):377. Stroup DF, Berlin JA, Morton SC, Olkin I,
Williamson D, Rennie D, et al. The site most frequently affected by malignant degeneration was the
pelvis (46 patients, 44%) with higher incidence in male patients (32 males vs.14 females). The second
one was lower limbs (including femur, fibula, or tibia), identified in 35 patients. The quantitative
analysis of empirical evidence can use a meta-analysis as the statistical approach. Further Reading:
Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. The PRISMA statement for reporting
systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation
and elaboration. PLoS Med. 2009 Jul 21;6(7):e1000100. Skeletal Radiol. 2005.. Pring ME, Weber
KL, Unni KK, Sim FH. The age at diagnosis of SPC ranges from 13 to 63, with median age at
diagnosis of 34 years. For the Internet in American presidential politics project, one methodological
approach would be to look at cultural differences between the portrayal of American presidents on
American, British, and French websites. CT manifestations Of the 11 tumors detected by ultrasound,
non-contrast enhanced CT showed five low density, three isodensity, one slightly high density and
two mixed density. Factors associated to a worse course of the disease were histological grade 2 and
3, and partial resection surgery. Investigation on prevalence of HBsAg and HBsAb in population
aged 1 to 69 years in Jiangxi Province in 2020. Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C,
Moran J, et al. Prevent plagiarism. Run a free check. In writing up the case study, you need to bring
together all the relevant aspects to give as complete a picture as possible of the subject. Systematic
reviews Authors of a systematic review ask a specific clinical question, perform a comprehensive
literature review, eliminate the poorly done studies, and attempt to make practice recommendations
based on the well-done studies. Our series comprises also patients younger than 30 years, including,
7 teenager patients had low grade SPC, except one. When you think your search is nearly final,
gather 2-3 of your most relevant articles and test their reference lists against your search results.
Shapiro-wilk test was used to determine the normality of the data. OR cross organisation OR cross
organization OR cross organizational OR. You can find protocols that will guide you from both
Cochrane and the Equator Network, among other places, and if you are a beginner to the topic then
have a read of an overview about systematic reviews.