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OVARIES
- Produces hormones that influence
the development of the secondary
female sexual characteristics, and ovulation by regulating the
maturation of the egg cells and estrogen-progesterone level
ovulation
- Located in the pelvic area
ENDOCRINE SYSTEM DISORDER
Hormones
Estrogen Progesterone Hormonal Imbalance - Organs and
Hormones do not produce the right
amount of chemicals needed leading to
dysfunctions
THE ROLE OF HORMONES IN THE
OSTEOPOROSIS
FEMALE AND MALE
REPRODUCTIVE SYSTEM - Bone is brittle and porous because
of reduced mineral density
Possible cause: Parathyroid hormone
- The pituitary gland controls the
secretion
function of both the testes and
ovaries
GOITER
- The endocrine system helps the
- Abnormal enlargement of the
reproductive system to function
Thyroid gland
properly
Possible cause: Underproduction or
overproduction of thyroid hormones
MALE SYSTEM
(STEPS)
GIGANTISM
1) Pituitary Gland releases FSH and LH
- Abnormal increase in height
2) FSH enters the testes and stimulates
Possible cause: Too much secretion of
Sertoli Cells (responsible for nourishing
growth hormones
the sperm cells)
3) LH also enters the testes and stimulates
DWARFISM
Leydig Cells - interstitial cells (makes and
- Short stature condition (PANDAK)
releases testosterone)
Possible cause: Insufficient growth
hormone
Testosterone - develops the male
secondary sexual characteristics and
MODULE 2
stimulates the sperm production in the
THE FEMALE REPRODUCTIVE
testes
SYSTEM AND THE MENSTRUAL
CYCLE
FEMALE SYSTEM
1) Follicles in the ovary produces estrogen
(controls the growth and release of eggs THE MENSTRUAL CYCLE
from the ovary) ● A series of changes during which
2) Progesterone also prepares the uterus an egg matures and the uterus is
so that the fertilized egg can grow prepared for possible pregnancy
3) Progesterone also prevents muscle
● It entails a biological feedback
contraction of the uterus to protect the egg
system
from detaching
● It is influenced by the endocrine
4) Together the FSH and LH affects the
system
development of the follicles and maturation
● Its average cycle is 28 days
of the egg as well as the process of
● Can continue for about 40 years
● Stops temporarily during - Occurs mid-cycle (around 2 weeks
pregnancy and resumes after or so before menstruation)
giving birth
Menstruation is a sign that a girl is
capable of producing offspring (baby) STEPS
(1) The mature egg from the follicle travels
Gonads are reproductive or sex organs down the fallopian tube (oviduct) and into
(testes and ovary) the uterus
● At any time during the egg’s
journey, sperm can fertilize it
● If fertilization does occur during this
phase, the egg continues to the
uterus
● The egg dies within 6 to 24 hours if
not fertilized
LUTEAL PHASE
- Includes the day after ovulation to
the day before your next period.
- The hormonal changes of this
phase are associated with
Premenstrual Syndrome (pimples,
headaches, fatigue, dizziness,
mood changes, bloating, pain,
swelling of the breast, and food
cravings)
AVERAGE
Menstruation: 1 - 7th Day
STEPS
Follicular: 1 - 14th Day
(1) LH and FSH levels decrease
Ovulation: 14th Day (Mid-Cycle)
(2) If the egg isn’t fertilized, the corpus
Luteal Phase: 15th Day until next
luteum degenerates and estrogen levels
Menstruation
decrease
FOLLICULAR PHASE
- Starts on day 1 of menstruation and CORPUS LUTEUM (STEPS)
ends with ovulation (day 14) (1) The follicle releases the egg
(2) The empty follicle turns into a Corpus
STEPS Luteum
(1) The Anterior Pituitary/Brain sends FSH (3) The corpus luteum produces
to the ovaries progesterone
(2) The FSH signals the follicles to grow
and mature
● IN SHORT
(3) The follicles then produce estrogen
(4) Estrogen then stimulates the thickening
Anterior Pituitary
of the Endometrium (Uterine Lining) in the
uterus
A. Follicle Stimulating Hormone (FSH)
(5) Once estrogen peaks, it signals the
- Stimulates follicular growth in
brain to release LH
ovaries
(6) LH triggers ovulation
OVULATION PHASE
- Stimulates estrogen secretion from direction. In your body, there are fewer
developing follicles (small sac examples of positive feedback because
containing the egg) they tend to amplify processes rather than
B. Luteinizing Hormone (LH) maintain balance. An example is childbirth.
- Surge causes ovulation When a woman goes into labor, the baby's
- Results in the formation of a corpus head pressing on the cervix causes the
luteum release of a hormone called oxytocin,
- Triggers corpus luteum to secrete which makes the contractions stronger.
progesterone Stronger contractions then cause more
pressure on the cervix, leading to even
Ovaries more oxytocin release and stronger
contractions. This continues until the baby
A. Estrogen is born, and the cycle stops.
- Thickens endometrium
- Stimulates the pituitary gland to Feedback Loops are biological processes
release LH causing ovulation that maintain homeostasis or body
- Stops FSH being produced so that balance.
only one egg matures in a cycle
B. Progesterone Negative Feedback: Reduces the effect
- Thickens endometrium of a Stimulus
- Inhibits FSH and LH during Luteal Positive Feeback: Intensifies a response
Phase
Negative feedback affects the
UNDERSTANDING FEEDBACK production and release of hormones in
MECHANISM the menstrual cycle.
Positive Feedback
Let's imaTransfer RNA (tRNA) correctly
and keep blowing air into it. As you blow
more air in, the balloon gets bigger, and
you want to keep blowing more air because
it's fun! This is like a positive feedback
system - it keeps going in the same
MODULE 3
NERVOUS SYSTEM:
The Control System of the Body
NERVOUS SYSTEM
(1) Initial
DNA and RNA work together to produce
- Involves the complementary
proteins from genetic codes
pairing of codons in mRNA with
anticodons in tRNA (a process
Genetic Codes facilitated by the ribosome
- Are found in DNA or RNA - Where the ribosome sandwiches
- Made up of nucleotide bases in the mRNA between its small and
three large subunit to be translated
- The first codon will be “AUG” (start
codon), and consequently codes
3 TYPES OF RNA
for the amino acid methionine
Mutations
- Changes to a DNA sequence
Mutagens
- Agents that cause alteration in the
DNA and can lead to permanent
mutations in the DNA sequence
Duplication
2 TYPES OF MUTATIONS - Occurs when a part of a
chromosome is copied (duplicated)
too many times
Hereditary/Germline Mutation - Can result in extra copies of genetic
- Inherited from parents material from the duplicated
- Present in almost all the cells in segment
bodies because they were inherited
one that was supposed to
be produced
● Nonsense: results in the formation
of a stop codon due to the
substitution of one base
VESTIGIAL
- Anatomical features or parts that Lamarck believed that short-necked
are usually reduced or with little to giraffes strained their necks to reach
no function in some organisms. food from trees causing their necks to
become longer. The acquired long necks
DARWIN of these giraffes were then passed on to
- He believed that the group of their offspring.
animals on each island is adapted
to a different way of life. ● Theory of Acquired
Characteristics (Traits): changes
acquired during an organism's
lifetime can be passed down to the - Non-random mating means that
offspring. sexual selection is not merely
based by chance but on some
CHARLES DARWIN physical and behavioral
- On the Origins of Species by characteristics
Menas of Natural Selection (1859) - The gene pool in non-random
- Suggested the theory of natural mating rapidly shifts so it contains
selection after he voyaged to only the desired alleles
Galapagos island aboard the HMS
Beagle; he observed that finches
For example, white rabbits preferentially
have different beak structures for
mate with rabbits of their color. Also,
various food types
some tall women prefer tall men rather
than short men.
● Theory of Natural Selection:
According to Darwin, originally,
giraffes had varying neck lengths. SYNTHETIC THEORY (Neo-Darwinian
Natural selection favored the synthesis)
survival of long-necked giraffes - Combination of Darwin’s evolution
because it allows them to reach for and the Mendelian principle of
food on tall trees while genetics
short-necked giraffes were - describes the evolution of life in
eliminated because of their inability terms of genetic changes occurring
to reach higher vegetation when in the population that lead to the
low vegetation is scarce such as formation of new species.
grasses. This eliminated them from
the population of giraffes. MUTATION
- Any change in chromosomes or
genes
GENETICS BASIS OF EVOLUTION
THE HARDY-WEINBERG EQUILIBRIUM
POPULATION GENETICS - Deals with the distribution of alleles
- Deals with the hereditary factors within the population
affecting a population - States that in a stable population,
- Gene flow occurs whether a allele frequencies remain constant
foreign individual interbreeds with from generation to another if
an individual of another population several conditions are met
resulting in a recombination of - Population must have unchanging
genes for different traits, increasing gene pool frequencies
the variation
For example, during the colonization EVOLUTIONARY PATTERNS
period in the Philippines, the gene pool
of the population was altered because
NATURAL SELECTION
the Spanish, American, and Japanese
- Nature selects organisms that will
soldiers had children with Filipino
or will not survive based on their
women.
existing traits
- The survivors will pass on their
ALLELE FREQUENCIES favorable traits to their offspring.
- Represent the fraction or
percentage of the population
carrying the allele
GENETIC DRIFT ● Parapatric (para=beside,
- Defined as a change in the gene patric=place): species spread out
pool due to chance alone over large geographical areas but
- Certain traits in the population individuals only mate with those in
could be reduced or eliminated their geographical region. Also,
through some unpredictable different habitats influence the
disasters or accidents such as development of different species
earthquakes, floods, fires, and and are separated by differences in
diseases the same environment, instead of
- Happens when a small population being separated by a physical
breaks off from a larger population barrier.
and forms a new population; the ● Sympatric (sym=same,
newly founded population patric=place): ecological
becomes different from the differences or random genetic
population of origin because of the changes occur in a small
acquired traits from the founder population that reproduces and
evolves within the population of the
For example, a flood wiped out a parent population. The two species
population of organisms and large land evolve together without any
vertebrate animals. Even when the geographical isolation.
animals have good traits adapted to their
habitat, such natural calamities may PUNCTUATED EQUILIBRIUM
affect their survival. Therefore, the - Proposed by Niles Eldredge and
survival or death in the population has Stephen Jay Gould in 1972
nothing to do with the general structure - Suggested that population
or physiology of the organism. demonstrate rapid change when
there is a need to survive sudden or
abrupt environmental changes
SPECIATION
- A process within evolution that MICROEVOLUTION
results in the formation of new, and - Is a change in gene frequency that
distinct species that are occurs within a population in short
reproductively isolated from other periods
populations
- There is no gene flow COEVOLUTION
- The process wherein a species
● Allopatric (allo=other, adapts or evolve in tandem with
patric=place): occurs due to another species as they interact
geographical isolation and both with each other
species evolve separately. Different
development of each species was
An example is the prey-predator
based on the demands of their
relationship between a bat and a moth.
unique habitat or the genetic
When the moth evolves due to
characteristics of the group that
environmental pressures, the bat will
passed on to offspring.
also evolve because it has a dependent
● Peripartic (peri=near,
relationship with the moth as the moth’s
patric=place): geographical
predator.
barriers separate the species at the
periphery isolating the small
population.
● Mimicry: ability of an organism to
CONVERGENT EVOLUTION imitate and copycat another
- The evolution of morphological species in terms of sound,
similarities in an organism that are appearance, smell, behaviour or
not closely related because they location to protect itself. Also refers
have similarities in their habitats. to the resemblance of an animal
species to another species or to
natural objects
An example of this is a marsupial mouse
that looks like a placental mouse. ● Chemical Defense: include
substances utilized by prey which
are harmful to invading organisms
ADAPTIVE RADIATION ● Body coverings: cover the body
- The process by which the species and protect animals from external
diversifies rapidly into different factors
types of closely related species
with each type occupying a new BEHAVIORAL OR HOW ANIMALS
environment RESPOND TO ACT OR TO LIFE NEEDS:
could be instinctive or happen naturally
An example of this type of evolution is
that of Darwin’s finches on Galapagos ● Hibernation: when animals bare
Island. sleep as a response to cold
weather and survive the cold winter