DRUG NAME CLASSIFICATION AND INDICATION AND SIDE EFFECTS AND SPECIAL PRECAUTIONS NURSING CONSIDRATIONS

MECHANISM OF ACTIONS CONTRAINDICATION ADVERSE EFFECTS

GENERIC NAME: CLASSIFICATION: INDICATION:  Pain and tenderness in 1. Avoid unnecessary or 1. Follow the 10 rights of
Dacarbazine Antineoplastics Treatment of metastatic the injection site prolonged exposure medication.
malignant melanoma. It is  Nausea and Vomiting to the sunlight or 2. Assess for signs of hepatotoxicity
also indicated to Hodgkin’s  Loss of Appetite wear protective and hepatic necrosis.
BRAND NAME: MECHANISM OF ACTION: disease as a secondary line  Flu-like illness clothing, sunglasses, 3. Watch for signs of allergic
Dtic-Dome Dacarbazine is an therapy when used in  Skin rashes and sunscreen. reactions and anaphylaxis.
anti-cancer agent, which combination with other  Alopecia 2. Do not drink alcohol 4. Monitor signs of leukopena,
DOSAGE: acts by different antineoplastic agents.  Photosensitivity beverages. thrombocytopenia, or unusual
200mg/Vial mechanism. It inhibit the  Leukopenia 3. Avoid people with weakness and fatigue that might
DNA synthesis by acting as  Thrombocytopenia infection. be due to anemia.
ROUTE: a purine analog, action as CONTRAINDICATION:  Anemia 4. See Doctor 5. Assess signs of parasthesia in
IV an alkylating agent and Contraindicated to patients immediately if there is the face or elsewhere.
interaction with SH group. who are hypersensitive to unusual bleeding or 6. Monitor IV injection site for pain,
FREQUENCY: the drug. Patient with renal bruising. swelling, and tissue necrosis.
and/or hepatic insufficiency. 7. Causes photosensitivity; use care
if administering UV treatments.
Advise patient to avoid direct
sunlight and use sunscreens and
protective clothing.
8. Instruct patient to guard against
infection and to avoid crowds and
contact with persons with
contagious diseases.
9. Advise patient about the
likelihood of GI reactions such as
nausea, vomiting, diarrhea, and
loss of appetite. Instruct patient
to report severe or prolonged GI
problems.
10. Advise patient that hair loss and
other skin reactions are likely to
happen.

Shiehan Mae B. Forro BSN 4-D GROUP 2

 DRUG NAME CLASSIFICATION AND INDICATION AND SIDE EFFECTS AND SPECIAL PRECAUTIONS NURSING CONSIDRATIONS
MECHANISM OF ACTIONS CONTRAINDICATION ADVERSE EFFECTS
GENERIC NAME: CLASSIFICATION: INDICATION:  Nausea 1. Avoid unnecessary or 1. Follow the 10 rights of medication.
Irinotecan Antineoplastics For the treatment of  Vomiting prolonged exposure to the 2. Assess for signs of hepatotoxicity
metastatic colorectal cancer.  Weakness sunlight or wear protective and hepatic necrosis.
Also used in combination  Leukopenia clothing, sunglasses, and 3. Watch for signs of allergic reactions
BRAND NAME: MECHANISM OF ACTION: with cisplatin for the  Anemia sunscreen. and anaphylaxis.
Camptosar Irinotecan inhibits the treatment of extensive small  Alopecia 2. Do not drink alcohol 4. Monitor signs of leukopena,
action of topoisomerase I. cell lung cancer. Also used in  Poor appetite beverages. thrombocytopenia, or unusual
DOSAGE: Irinotecan prevents combination with fluorouracil  Fever 3. Avoid people with weakness and fatigue that might be
200mg/Vial religation of the DNA strand and leucovorin for the  Weightloss infection. due to anemia.
by binding to topoisomerase treatment of patients with  Constipation 4. See Doctor immediately 5. Assess signs of parasthesia in the
ROUTE: I-DNA complex. The metastatic adenocarcinoma  Shortness of breath if there is unusual bleeding face or elsewhere.
IV formation of this ternary of the pancreas after disease  Insomia or bruising. 6. Monitor IV injection site for pain,
complex interferes with the progression following  Cough swelling, and tissue necrosis.
FREQUENCY: moving replication fork, gemcitabine-based therapy.  Dehydration 7. Causes photosensitivity; use care if
which induces replication  Skin rash administering UV treatments. Advise
arrest and lethal CONTRAINDICATION:  Swelling of feet and patient to avoid direct sunlight and use
double-stranded breaks in Contraindicated to patients ankle sunscreens and protective clothing.
DNA. As a result, DNA who are hypersensitive to 8. Instruct patient to guard against
damage is not efficiently the drug. infection and to avoid crowds and
repaired and apoptosis contact with persons with contagious
(programmed cell death) diseases.
occurs. 9. Advise patient about the likelihood
of GI reactions such as nausea,
vomiting, diarrhea, and loss of
appetite. Instruct patient to report
severe or prolonged GI problems.
10. Advise patient that hair loss and
other skin reactions are likely to
happen.

Shiehan Mae B. Forro BSN 4-D GROUP 2

 DRUG NAME CLASSIFICATION AND INDICATION AND SIDE EFFECTS AND ADVERSE SPECIAL PRECAUTIONS NURSING CONSIDRATIONS
MECHANISM OF ACTIONS CONTRAINDICATION EFFECTS

GENERIC NAME: CLASSIFICATION: INDICATION: 1. Avoid unnecessary or 1. Follow the 10 rights of medication.
 Nausea,
Oxaliplatin Antineoplastics, Ankylating Oxaliplatin, in combination prolonged exposure to 2. Assess for signs of hepatotoxicity
with infusional fluorouracil  Vomiting, the sunlight or wear and hepatic necrosis.
MECHANISM OF ACTION: and leucovorin, is indicated protective clothing, 3. Watch for signs of allergic reactions
 Diarrhea,
BRAND NAME: Oxaliplatin is a platinum for the treatment of sunglasses, and and anaphylaxis.
Eloxatin derivative that functions as advanced colorectal cancer  Numbness, sunscreen. 4. Monitor signs of leukopena,
an alkylating agent. It forms and adjuvant treatment of 2. Do not drink alcohol thrombocytopenia, or unusual
DOSAGE: both inter- and intra-strand stage III colon cancer in  Tingling, beverages. weakness and fatigue that might be
200mg/Vial cross links in DNA, which patients who have  Burning pain, 3. Avoid people with due to anemia.
prevent DNA replication and undergone complete infection. 5. Assess signs of parasthesia in the
ROUTE: transcription, resulting in resection of the primary  Mouth sores 4. See Doctor face or elsewhere.
IV cell death. The exact tumor  Tiredness. immediately if there is 6. Monitor IV injection site for pain,
mechanism of action of unusual bleeding or swelling, and tissue necrosis.
FREQUENCY: oxaliplatin is not known, but CONTRAINDICATION:  Swelling of the face, lips, bruising. 7. Causes photosensitivity; use care if
it is believed to inhibit DNA Hypersensitivity to tongue, or throat, administering UV treatments. Advise
synthesis by forming oxaliplatin and other patient to avoid direct sunlight and use
interstrand and intrastrand platinum agents.  Shortness of breath, sunscreens and protective clothing.
cross-linking of DNA Myelosuppression,  Confusion, 8. Instruct patient to guard against
molecules. peripheral sensory infection and to avoid crowds and
neuropathy w/ functional  Sweating, contact with persons with contagious
impairment, congenital long  Itching, diseases.
QT prolongation. Severe 9. Advise patient about the likelihood
renal impairment Lactation.  Chest pain, of GI reactions such as nausea,
Concomitant use w/ live  Dry cough, vomiting, diarrhea, and loss of
vaccines. appetite. Instruct patient to report
 Pain, redness, swelling, severe or prolonged GI
or skin changes where problems.Advise patient that hair loss
and other skin reactions are likely to
the injection was happen.
given,feeling very thirsty
or hot,

Shiehan Mae B. Forro BSN 4-D GROUP 2

 ASSESSMENT NURSING DIAGNOSIS OUTCOME IDENTIFICATION NURSING INTERVENTIONS RATIONALE EVALUATION
SUBJECTIVE: Risk for Infection related to SHORT TERM INDEPENDENT: SHORT TERM
inadequate secondary After 4 hours of nursing 1. Check and monitor the patient’s 1. An increase in the patient’s After 4 hours of nursing
defenses, intervention the patient will be vital signs, especially the temperature may happen intervention the patient was
immunosuppression able to identify and participate temperature, and check the skin, because of various factors such able to identify and participate
secondary to chemotherapy. in interventions that will prevent genitourinary, and respiratory as chemotherapy side effects, in interventions that will
and decrease the risk of system of the patient. disease process, or infection. prevent and decrease the risk
infection. 2. Instruct and encourage the Identifying the infectious of infection.
patient, staff, and visitors about process enables appropriate
OBJECTIVE: RATIONALE: LONG TERM: good hand washing procedures and intervention to be given to the LONG TERM:
VITAL SIGNS: Infection is one of the most After 1 week of nursing emphasize proper personal hygiene. patient to avoid complications. After 1 week of nursing
T- 37.6 Common complications of intervention the patient will Limit and screen visitors that may 2. Handwashing will protect the intervention the patient is
BP- 120/90 chemotherapy. There is an remain free from infection and have an infection and place them in patient from different sources of remain free from infection and
O2SAT- 98% increased risk of infection in will be able to achieve timely reverse isolation if indicated. infection such as visitors and will be able to achieve timely
PR- 90 bpm clients with chemotherapy healing as appropriate. 3. Change the position of the staff who are experiencing an healing as appropriate.
RR - 18 cpm treatments due to patient frequently and always keep upper respiratory infection.
destruction the linen of the bed dry and Limiting a potential source of
of rapidly dividing wrinkle-free. infection is important to cancer
Hematopoietic cells, patients.
resulting DEPENDENT: 3. The repositioning will decrease
In immunosuppression. 4. Give medications such as pressure and irritation to the
antibiotics as indicated and as patient’s tissue and will prevent
prescribed by the physician. skin breakdown that potentiates
5. Change IV tubing the site for bacterial growth
according to your facility’s policy. 4. Medications may be used to
Use strict sterile treat infections and may be
technique and metal scalp vein given prophylactically in
needles (metal butterfly needle) immunocompromised patients.
when starting IV. 5. IV sites can harbor infection.
Additional measures to avoid
COLLABORATIVE: infection.
6. Check and monitor the patient’s 6. An increase in WBC or white
CBC result including the WBC and blood cell count indicates
granulocyte count and the platelet infection and inflammation.
as indicated. Monitoring the CBC will help in
preventing further infection and
complications.

Shiehan Mae B. Forro BSN 4-D GROUP 2

 ASSESSMENT NURSING DIAGNOSIS OUTCOME IDENTIFICATION NURSING INTERVENTIONS RATIONALE EVALUATION
SUBJECTIVE: Acute Pain SHORT TERM 1. Assess pain 1. Breast cancer can cause pain due to the SHORT TERM
“ masakit ang akon Related to chemotherapy After 4 hours of nursing appropriately. tumor(s) or from the cancer treatments. After 4 hours of nursing
dughan,: as verbalized by as evidenced by intervention Patient will The nurse can assess pain by asking the intervention Patient can
the patient. verbalization of pain verbalize pain is reduced or 2. Assess pain with vital patient their pain level on a 0-10 scale or verbalize pain is reduced
controlled signs. using a nonverbal pain scale if the patient or controlled
is unable to rate.
LONG TERM: 3. Examine the patient’s 2. Elevated blood pressure, tachycardia, LONG TERM:
After 1 week of nursing cultural norms regarding and tachypnea are often seen along with After 1 week of nursing
intervention the Patient will pain expression. complaints of pain. The nurse can assess if intervention the Patient
RATIONALE: demonstrate the ability to pain is controlled or not by assessing for can demonstrate the
OBJECTIVE: Infection is one of the most
Pain scale: 8/10 perform ADLs due to 4. Administer pain changes in vital signs. ability to perform ADLs
Common complications of improved comfort. medication as 3. Some cultures display pain openly, while due to improved comfort .
VITAL SIGNS: chemotherapy. There is an
U- 37.6 prescribed. others do not. The nurse can address this
increased risk of infection in
BP- 120/90 by assessing for pain often, using verbal
clients with chemotherapy
O2SAT- 98% treatments due to
5. Evaluate the and nonverbal pain scales, and remaining
PR- 90 bpm destruction effectiveness of pain understanding and nonjudgmental towards
RR - 18 cpm of rapidly dividing medication. the patient’s beliefs.
Hematopoietic cells, 4. Patients being treated for breast cancer
resulting 6. Educate patients about often require a combination of opioids and
In immunosuppression. side effects and NSAIDs along with antiemetics
treatment. for nausea caused by chemotherapy to
relieve pain and discomfort.
5. After pain medications are
administered, evaluate the effectiveness
regularly.
6. Inform the patient about what to expect
regarding side effects of chemotherapy,
radiation, and other treatments which are
often uncomfortable.
7. Educate and encourage patients to be
honest about their pain and communicate
regularly with their provider

Shiehan Mae B. Forro BSN 4-D GROUP 2