Histology - Laboratory

Exercise 5: Integumentary System

OBJECTIVES:
1. To analyze photomicrographs and histological pictures of the skin and its
appendages
2. To correlate histological changes of the skin with some diseases and disorders
3. To strengthen the values of responsibility and orderliness

GROUP # SCORE
PROGRAM & ITEMS 30
SECTION
Last Name, First Name Assigned Role Contribution/s

Instructions
 Complete the following tables by attaching the required photomicrographs/
 illustrating the corresponding tissues/structures
 Label the key structures
 Every member is required to upload the accomplished laboratory activity to
canvas

Structure:
The epidermis is the outermost of three skin layers, followed by the dermis and
hypodermis.
It's typically around 0.05 millimeters thick, varying slightly across different body
regions.
It lacks blood vessels and relies on the underlying dermis for nourishment and waste
removal.
The epidermis is composed of four to five distinct layers, each with specific functions:
o Stratum basale (basal layer): The deepest layer, where new skin cells are
continuously produced.
o Stratum spinosum (spinous layer): Cells start to differentiate and acquire more
structure.
o Stratum granulosum (granular layer): Keratin production begins, making the
cells tougher.
o Stratum lucidum (clear layer): Present only in thicker skin areas like palms and
soles, contains flattened, translucent cells.
o Stratum corneum (horny layer): The outermost layer, made of dead, flattened
keratinized cells, providing the skin's waterproof barrier.
Functions:
 Protection: The primary role of the epidermis is to shield your body from harmful
external elements like:
o Pathogens: Bacteria, viruses, and fungi.
o Physical damage: Cuts, scrapes, and UV radiation.
o Chemicals and irritants.
o Excessive water loss, maintaining hydration.
 Sensory perception: Nerve endings in the epidermis enable sensations like
touch, pressure, and pain.
 Vitamin D production: The epidermis helps synthesize vitamin D with sun
exposure, crucial for bone health.
 Skin tone: Melanin, produced by melanocytes in the epidermis, determines your skin
color and offers some protection from UV rays.
Epidermis
Total Magnification 100X
Reference Crumbie, Lorenzo. “Skin Histology.” Kenhub, 27 Oct. 2022,
www.kenhub.com/en/library/anatomy/histology-of-the-skin.
 Dermis
Total Magnification
Reference

Hair
Total Magnification
Reference
 Nail
Total Magnification
Reference

Sebaceous glands
Total Magnification
Reference
 Sudoriferous glands
Total Magnification
Reference

Tactile receptor/s
Total Magnification
Reference