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Development of the

Discovery of Cells
Alexis Abogado, Kyle Ilan, Rose Orbillo, Noelle Savilla, and Sheilla Tabigan
SIKAP
S Every member K The members
will apply these
P
researched
knowledge
about cells and
through
contributed on reporting and
making the sharing it to
presentation. you.

The Each and every


knowledge member will be
To understand
gained by the given a chance
the history of to present their
members will
cells be presented ideas about this
I discussion.
later.
A
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Cell Discovery Timeline
1595 1838
Zacharias Jansen credited with 1st Matthias Schleiden and Theodor
compound microscope. Schwann proposed the cell theory.

1840
1655 Albrecht von Roelliker realized
Robert Hooke described cells in that sperm cells and egg cells are
cork. also cells.

1674 1856
Anton van Leeuwenhoek Nathanael Pringsheim observed
discovered protozoa. He saw how a sperm cell penetrated an
bacteria 9 years later egg cell.

1833 1857
Robert Brown described the cell Albert von Kolliker described
nucleus in cells of the orchid. mitochondria.

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1858 1938
Rudolf Virchow expounds his Behrens used differential
famous conclusion: omnis cellula centrifugation to separate nuclei
e cellula, that is cells develop only from cytoplasm.
from existing cells.
1939
1879 Ernst Werner Siemens produced
Walther Flemming described the first commercial transmission
chromosome behavior during electron microscope.
mitosis.

1883 1952
Germ cells are haploid, George Otto Gey and coworkers
chromosome theory of heredity. established a continuous human
cell line.

1955
1898 Harry Eagle systematically
Camillo Golgi described the golgi
defined the nutritional needs of an
apparatus.
animal cell in culture.

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1957
Matt Maselson, Franklin Stahl and 1981
Jerome Vinograd developed density Transgenic mice and fruit flies are
gradient centrifugation in cesium produced. Mouse embryonic stem
chloride solutions foe separating cell line established.
nucleic acids.
1995
1965 Roger Tsien identifies mutant of
Kenneth Alfred Ham introduced a GFP with enhanced spectral
defined serum-free medium. properties.
Cambridge Instruments produced
the first commercial scanning
electron microscope.
1998
Mice are cloned from somatic
cells.
1976
Gordon Sato and colleagues
1999
publish papers showing that
Hamilton and David Baulcombe
different cell lines require
discover siRNA as part of post-
different mixtures of hormones
transcriptional gene silencing
and growth factors in serum-free
(PTGS) in plants.
media.

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