– Observed the world in tiny drop of water and explained with attractive drawings. • Robert Hooke – studies dead cells of bark of an Oak tree for the first time under microscope. • Cells show tiny organs - Organelles • The small photograph through microscope - Micrograph SIZE OF THE CELL • With the minimum size,a cell must be able to house enough DNA , protein molecules and internal structures to survive and reproduce. • At maximum, the size of the cell is influenced by its requirement for enough surface area to obtain adequate nutrition and oxygen and dispose off the waste. • A large cell has more surface area than a small cell, but less surface area Relative to their volume. The well developed – Eukaryotic cells • A eukaryotic cell comprise of many varied however, interconnected structures. • Such as Nucleus and the surrounding fluid - Cytoplasm. • The outermost protective coverings are Cell Wall or Plasma Membrane. • The small organs suspended in the cytoplasm are called as Organelles – Membranous organelles, making compartments performing different activities. • The chemical activities occurring in the cells – Cellular Metabolism. • The organelles forms their own membranes giving additional benefit of surface area. • This enhances formation of necessary proteins such as enzymes or hormones. • Cell Wall – Complex carbohydrate – Cellulose Freely permeable. • Plasma membrane – Fats / Lipids + proteins = Lipoproteins. Selectively permrable. Eukaryotic cell Size Comparison Nucleus – The controlling centre • A separate compartment – Nuclear envelope – Double membrane, perforated. • Contains a highly coiled up- Chromatin- genetic material – DNA ( De-oxyribose nucleic acid). • At the time of cell division , it greatly coils uo and dehydrates forming the countable Chromosomes. • Its own cytoplasm – Nucleoplasm • Nucleolus – A dark body inside is the production site for the protein factories of the cell ie Ribosomes. Endo-membrane system a) Endoplasmic reticulum The Endomembranous system has many cell organelles which are interconnected • ENDOPLASMIC RETICULUM : A network inside the cytoplasm of the cell. • In continuation with the nuclear envelope , rise of the reticulum is seen. • RER – Transportation of proteins prepared by the ribosomes. • SER – Transportation and storage of fats/lipids. Detoxification of body at regular basis and under heavy medication. Endo-membrane system b)Golgi bodies- The packaging & dispatching units Camillo Golgi –Golgi apparatus Endo-membrane system c )Lysosomes –Cleaners and helpers • Golgi apparatus produce many vesicles are released containing different proteins. • Some of them contains digestive enzymes and are called as “ Lysosomes”. – Lytic/ breaking down ; soma – body. • Lysosomes digests the cell debris, excess materials and organelles of the cell. • Hence are known as “ Demolition squad”. • When the cell is damaged or is about to die, lysosomes burst open to digest the whole cell. • Hence are alos known as “ Suicidal bags” of the cell. • The cytoskeleton is a network of filaments and tubules that extends throughout a cell, through the cytoplasm, which is all of the material within a cell except for the nucleus. • It is found in all cells, though the proteins that it is made of vary between organisms. a) Microfilaments : forms a three dimensional network supporting the cell’s shape. Ex. Muscle cells, Amoeba and amoeboid movement shown by some of the blood cells such as WBC. b) Intermediate filaments : Fibrous proteins ,ropelike, provides anchorage to certain organelles such as nucleus. c) Microtubules : Tubulin proteins, providing rigidity and shape to the cell . Also provides tracks for organelles to move within the cytoplasm. • Locomotary organs : • Flagella : - A long tail like organ found in the prokaryotic cells. In eukaryotes, human male reproductive cells, show flagella. • They also show small hair like organ such Pili ( singular Pilus). • Cilia :- small hairy organs covering the animals body surface or any organ inside an animal’s body on the organs for better absorption. CELL JUNCTIONS