Which of the following is FALSE with

respect to the class of biomolecules

known as lipids?

A. Lipids are hydrophobic.

B. Humans love the taste of lipids.
C. Cholesterol is a steroid, not a
lipid.
D. Lipids are essential in the human
diet.

Chapter 12
 Which of the following statements
regarding trans fat is false?
A. Trans fats occur naturally in milk and body fat of cows
and sheep.
B. Certain foods may contain 45% of their total fat
content as trans fat.
C. Trans fat raises LDL (“bad” cholesterol) levels in the
bloodstream, but does not lower HDL (“good”
cholesterol) levels.
D. The largest amount of trans fat consumed today is
created by the processed food industry as a side-
effect of partially hydrogenating unsaturated plant
fats (generally vegetable oils).

Chapter 12
Answer True (A) or False (B)
for the following statements.
• Fatty acids always contain an even number of
carbon atoms.

• Glycerophospholipids are amphiphilic molecules due

to the presence of a nonpolar phosphoryl head
group and a polar hydrocarbon tail.

• Polyunsaturated fatty acids have a lower melting

temperature than saturated fatty acids.

Chapter 12
 Arrange the following in order of the greatest to
least contribution to the ability of fatty acids to pack
together.

1. Short unsaturated tail

2. Short saturated tail
3. Long unsaturated tail
4. Long saturated tail

A. 1, 2, 3, 4
B. 3, 4, 1, 2
C. 4, 2, 3, 1
D. 2, 4, 1, 3

Chapter 12
Which of the following group of fatty
acids predominate in coconut oil?

A. C16 and C18 saturated.

B. C4 to C14 saturated.
C. C16 and C18 monounsaturated.
D. C14 to C18 polyunsaturated

Chapter 12
 Can a pure sample of cholesterol
form an artificial bilayer when mixed
with water?
A. Yes, as cholesterol is weakly amphiphilic.

B. Yes, as cholesterol is amphipathic and has

the correct shape for close packing.

C. No, as cholesterol is almost entirely

hydrophobic.

Chapter 12
 Why are glycerophospholipids capable of
spontaneously assembling into the bilayer structure
found in biological membranes but triacylglycerols are
not?
A. Glycerophospholipids are amphipathic and aggregate
into bilayers that can interact with water on both faces.
B. Triacylglycerols have three acyl chains that do not align
easily side-by-side to form a bilayer.
C. Triacylglycerols are not amphiphilic.
D. Both A and B are true.
E. All of the above are true.

Chapter 12
Which of the following statement(s) about the fatty
acid shown below is FALSE?

A. It is unsaturated.
B. It forms a bilayer when mixed with water.
C. It can be a component of glycerophospholipids but not
sphingolipids.
D. It is amphipathic.
E. Both B and C are false.
Chapter 12
In humans, the fatty acid composition of membrane
lipids in skin cells is different from the fatty acid
composition of membrane lipids in the internal organs,
because the internal organs function at a slightly higher
temperature. Which of the following differences in fatty
acid composition is most likely to be observed?

A. Skin cells show higher levels of 20:0 relative to 16:0

AND higher levels of 18:2 relative to 18:0.
B. Skin cells show higher levels of 20:0 relative to 16:0
AND lower levels of 18:2 relative to 18:0.
C. Skin cells show lower levels of 20:0 relative to 16:0
AND higher levels of 18:2 relative to 18:0.
D. Skin cells show lower levels of 20:0 relative to 16:0
AND lower levels of 18:2 relative to 18:0. Chapter 12
Which of the following statement(s) about the fatty
acid shown below is True?

A. It is saturated.
B. It forms a bilayer when mixed with water.
C. It is a component of membrane lipids.
D. It is amphiphilic.
E. Both C and D are True.

Chapter 12
Which of the following is NOT a general feature of
the lipid bilayer in biological membranes?

A. Integral membrane proteins penetrate or span the

lipid bilayer, interacting only with hydrophobic lipid
acyl chains.
B. The thickness of membrane bilayers varies
depending on the fatty acids incorporated in the
lipids.
C. The forces that stabilize the lipid bilayer are the
same forces that stabilize the tertiary structure of
proteins.
D. Peripheral membrane proteins associate non-
covalently with hydrophilic lipid head groups of the
bilayer.

Chapter 12
 Which of the following statements
CORRECTLY describes the molecule whose
structure is shown below?

CH3(CH2)15PO3- CH2CH2 N+(CH3)3

A. This molecule is a glycerophospholipid.

B. This molecule is likely to cross the membrane by
diffusion.
C. This molecule is amphiphilic.
D. None of the above statements are correct.

Chapter 12
A protein studied in the lab readily dissociates
from the cell plasma membrane. What type of
protein is this most likely to be?

A. An intrinsic membrane protein.

B. A peripheral membrane protein.
C. An ion channel protein.
D. A lipid-linked protein.

Chapter 12
 Which one of the following sequences of five amino
acids would most likely be located on the surface of
the transmembrane portion of an integral membrane
protein?

A. Tyr-Phe-Glu-Asn-Leu
B. Glu-Asn-Ser-Thr-Gln
C. Met-Phe-Pro-Ile-Leu
D. Val-Thr-Val-Glu-Val
E. Gly-Arg-Ser-Asp-Gln

Chapter 12
 Which of the structures shown below illustrate the
distinct structural features of porins?

A. A and C
B. A and D
C. B and D
D. B and C

Chapter 12
 The Following are Microscopic Images
of Lipoproteins all at the same degree of
magnification. Which shows VLDL?

A. A
B. B
C. C
D. D

Chapter 12
 Which image shows the lipoprotein
that contains most cholesterol (% dry
wt.)?

A. A
B. B
C. C
D. D

Chapter 12
Which image shows the lipoprotein
that transports fats from the liver to
other tissues?

A. A
B. B
C. C
D. D

Chapter 12