Ivabradine Classification: antianginal agent Drug Action: acting by selective and specific inhibition of the cardiac pacemaker; controls

the spontaneous diastolic depolarisation in the sinus node and regulates heart rate. The cardiac effects are specific to the sinus node with no effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarisation Indication/s: This medication is a cardiotonic agent, prescribed for angina pectoris. It helps to lower the heart rate Contraindication/s: Contraindicated in patients with severe heart disease, and hypersensitivity. It should not be administered along with calcium channel blockers. Adverse Reaction/s: Heart - Slow heart rate, palpitations, heart block, abnormal heart rhythm, difficulty in breathing and fainting. Central Nervous System - Headache, and dizziness. Eye - Blurred vision. Gastrointestinal - Nausea, vomiting and constipation. Blood -

Eosinophilia. Musculoskeletal - Muscle cramps and muscle weakness. Nursing Responsibilities: 1) Monitor BP and pulse before therapy, during dosage titration, and periodically throughout therapy. 2) Assess for signs of CHF (peripheral edema, crackles, dyspnea, weight gain, jugular venous distention). 3) Angina: Assess location, duration, intensity and precipitating factors of patient's anginal pain. 4) Hypertension: Check frequency of refills to monitor adherence. 5) Monitor serum potassium periodically. Hypokalemia increases the risk of arrhythmias and should be corrected.