-

Allopurinol

trade name (strength) indications/dose

max.dose/ special
population
Zyloric (100, 300 hyperuricemia/ gout:
800 mg/day;
mg); Zylic, Allopin, 200-300 mg OD (mind)
Alloric
200-300 mg bid (severe) Clcr < 60
200 mg OD,
50
mg Clcr
20 ml/min

S/E & ADRs

interactions

contraindication precautions

acute gout attack, N/V,

abnormal liver function
tests, hypersensitivity
reactions, rash, vasculitis,
SJS, blood toxicity

phenytoin,

azathioprine,
allopurinol
cyclophosphamide,
didanosine, mercaptopurine,
theophyline;
ACEIs, thiazide
diuretics
allopurinol

Tenomin (50, 100

mg); Prenolol

bradycardia, heart block,

hypotension, dizziness,
Reynaud s phenomenon,
bronchoconstriction, sexual
dysfunction

heart block
non-DHP CCB, digoxin;

beta-2 agonist

preg (C )

, ,
,

special information

100 mg OD
1-2

Atenolol

HTN: 25-50 mg OD
Angina pectoris: 50 mg
OD
Post MI: 100 mg OD or
50 mg bid 6-9 days

100 mg/day; Clcr

15-35 ml/min
50 mg OD,
Clcr <15 ml/min
50 mg

atenolol, preg (D )
sinus

bradycardia, asthma/COPD
heart block

;
DM
hypoglycemia

RxCU 71 /.

Amitriptyline

Tryptanol (25 mg); Depression: 50-150 mg 400 mg/day

Tripta, Triptyline OD hs
(10, 25, 50 mg)
Migraine prophylaxis:
10-400 mg/day
50 mg/day
2-3

orthostatic hypotension,
heart block; anticholinergic:
dry mount, constipation,
urinary retention, papitation,
blurred vision; CNS:
drowsiness, sedation,
fatigue, headache,
nightmare, confusion

amitriptyline CYP2D6
substrate
Amitirptyline,
MAO MI
inhibitor,

preg (C );

24

Amlodipine

Norvasc (5, 10 mg); Angina: 5-10 mg OD

Amlopine
HTN: 2.5-10 mg OD

10 mg/day

peripheral edema,
amlodipine CYP3A4

hypotension, reflex
substrate CYP1A2/ amlodipine
tachycardia, flushing,
3A4 inhibitor
dizziness, sexual dysfunction phenytoin, tacrolimus

preg (C );
2-3
reflex tachycardia
angina MI

Amoxycillin

Amoxil (500 mg,

125 mg/5ml, 250
mg/5ml); Siamox,
Ibiamox (250, 500
mg, 125 mg/5ml,
250 mg/5m)

3000 mg/day; Clcr

10-30 ml/min 250500 mg q 12 hr,
Clcr <10 ml/min
250-500 mg q 24 hr

confusion, anxiety,
dizziness, headache,
insomnia, seizure, blood
toxicity, hepatitis, jaundice,
cystaluria;
hypersensitivity reaction:
rash, anaphylaxis

preg (B );

pseudomembranous
colitis

pediatric infections: 2050 mg/kg/day q8-12 hr

pediatric otitis media:
80-90 mg/kg/day q12 hr
Adult infections: 250500 mg q 8 hr or 1000
mg q 12 hr

methotrexate
BCG vaccine,
typhoid vaccine,
mycophenolate
allopurinol probenecid

amoxicillin

amoxicillin

beta-lactams

RxCU 71 /.

Aspirin

Aspent (81, 300

mg); Aspilets
(chewable 80 mg),
cardiprin (100 mg)

analgesic/antipyretic: 5.4 g/day

325-650 mg q4-6 hr
anti-inflammation: 3.65.4 g/day pc divided tidqid
antiplatelet: 50-325
mg/day pc OD

N/V, GI disturbance, peptic

ulcers/bleeding, bleeding
tendencies, blood loss,
bronchoconstriction,
angioedema, anaphylaxis,
metabolic acidosis

;
enteric coated tablet
antacid,
calcium
2

aspirin
NSAIDs;
active
bleeding
disorders
major bleeding

preg (C/D); non-active

bleeding disorders,
,

(polyp)

aspirin NSAIDs

Azithromycin

Zithromax (250 mg,

200 mg/5 ml);
Azith, Azithro
Zmax (ER susp 2
g/60 ml)

pediatric infections: 500 mg/day

5-12 mg/kg/day OD ac 1500 mg/single dose
adult infections:
250-500 mg OD ac
Zmax 2 g single dose ac

diarrhea, N/V, abdominal

pain/discomfort, hepatitis,
abnormal liver function
tests, skin rash, pruritus

BCG vaccine,
typhoid vaccine

macrolides

preg (B );
Zmax " "
"

"
pseudomembranous
colitis

Bisacodyl

Dulcolax (5 mg
Laxative: 5-10 mg po po 30 mg/day;
Ectab; 5mg, 10 mg OD hs 5-10 mg
suppo 10 mg/day
suppositories)
suppo OD am
bowel evacuation: 1530 mg po OD

diarrhea, N/V, abdominal

pain/discomfort, cramping,
fluid/electrolyte imbalance,
hypokalemia

enteric coated tablet

antacid,
calcium
2 ;

preg (C ); rectal suppositories
bisacodyl,
;

cathatic colon

RxCU 71 /.

Calcium
carbonate

chalkcap (850, 1000 antacid: 600-1250 mg antacid: 7000

mg); calcap, caltab chew before swollow q mg/day
2-4 hr prn
hypocalcemia: 850 mg
po bid pc 1000 mg
po bid pc
osteoporosis: 1000-1500
mg/day po OD pc
phosphate binder: 6501000 mg tid with meal

headache,
hypophosphatemia,
hypercalcemia, constipation,
acid rebound, N/V,
flatulence

levothyroxine,
tetracyclines, beta-blockers,
quinolones, bisphosphonates,
ferrous salts; pH

enteric-coated

hypercalcemia,
renal calculi,
hypophosphate
mia

preg (A );

milk-alkali syndrome

;
phosphate binder

Cephalexin

Keflex (250 mg cap,

500 mg cap, 125
mg/5 ml); ibilex,
cephin

pediatric infections: 25100 mg/kg/day q 6-8 hr

adult infections: 2501000 mg q6 hr
adult uncomplicated
cystitis: 500 mg q 12 hr

pediatric & adult: 4

g/day; Clcr 10-50
ml/min: 500 mg q 812 hr, Clcr<10
ml/min: 250-500
mg q 12-24 hr

agitation, confusion,
dizziness, fatigue, headache,
angioedema, urticaria, rash,
SJS/TEN, anaphylaxis,
abdominal pain, N/V,
abnormal liver tests, blood
toxicity, interstitial nephritis

BCG vaccine,
typhoid vaccine; probenecid

cephalexin

penicillins
cephalosporins

anaphylaxis/urti
caria

preg (B );
penicillins
cephalosporins
IgE-mediated;
pseudomembranous
colitis

Cetirizine

Zyrtec (10 mg,

1mg/ml); Cettec

allergic rhinitis,
urticaria, other allergic
symptoms: 6-12 mo: 2.5
mg OD; 1-5yo: 2.5 mg
OD-bid; >5 yo 5-10 mg
OD

10 mg/day; Clcr 11- headache, somnolence,

30 ml/min,
insomnia, fatigue, N/V,
hemodialysis,
diarrhea
hepatic impairment
5 mg OD

10

CNS suppressants, cetirizine,
alcohol
hydroxyzine

preg (B );

11

RxCU 71 /.

Chlorpheniramin Pititon (4 mg);

e
various (2,4 mg, 2
mg/5 ml)

po 24 mg/day,
allergic rhinitis,
rhinorrhea, urticaria, IM/IV 40 mg/day
other allergic
symptoms: 2-6 yo: 0.35
mg/kg/day q 4-6 hr, 6-12
yo: 2 mg q 4-6 hr, >12
yo: 4 mg q 4-6 hr

drowsiness, secretion
thickened, headache,
fatigue, dizziness,
somnolence, excitement,
anticholinergics,
constipation, weakness

CNS suppressants,
alcohol;
MAOIs, anticholinergics

Chlorpromazine Chlopazine,
Chlorpromed (100,
200 mg); matcine,
pogetol (25, 50, 100
mg)

2 g/day;
psychoses:30-600

mg/day divided 1-4
doses;
intractable hiccups: 2550 mg tid-qid;
N/V: 10-25 mg q4-6 hr

postural hypotension,

tachycardia, QT change,
CNS suppressants,
dizziness, drowsiness, EPS alcohol;
symptoms, seizure, skin
pigmentation, lactation,
anticholinergics

CPM, preg (B ); narrow

angle glaucoma,
urinary retention

12

preg (C );
chlorpromazine,

phenothiazines,
severe CNS

depression,
coma

13

Ciprofloxacin

Ciprobay (250, 500 pediatric infections: 20mg); cifloxin

30 mg/kg/day po q12 hr
adult infections: 250750 mg po q12 hr
urethral gonococcal
infection: 500 mg as a
single dose

1500 mg/day; Clcr

30-50 ml/min: 250500 mg q 12 hr,
Clcr <30 ml/min:
250-500 mg q24 hr

dizziness, insomnia,
somnolence, fever, rash,
phototoxicity, N/V, GI
discomfort, abnormal liver
tests, blood toxicity,
tendonitis/rupture

ciprofloxacin CYP1A2
inhibitor
quinolones;
sulfonylureas, theophyllines, tizanidine
warfarin, tizanidine

preg (C );

14

RxCU 71 /.

Clarithromycin Klacid (250, 500

mg, 500 MR tab);
Claron, Clacina

pediatric infections: 7.5 pediatric: 500

mg/day; adult: 1000
mg/kg q12 hr
mg/day; Clcr <30
adult infections:
250-500 mg q12 hr ml/min: 50% of
500-1000 mg MRtab OD usual dose

headache, rash, abnormal

taste, N/V, GI discomfort,
abnormal liver tests, BUN
increased

strong inhibitor CYP3A4

vinca alkaloids,
cilostazol, colchicine, ergot
derivatives, fentanyl

macrolides;
ergot
derivatives,
pimozide,
cisapride,
colchicine

Clindamycin

Dalacin (150, 300

mg, acne sol 10
mg/ml); clindavid,
rosil, klindamycin

pediatric infections: 8- pediatric: po 40

20 mg/kg/day po divided mg/kg/day; adult:
po 1.8 g/day
3-4 doses
adult infections: 150450 mg po q 6-8 hr

Gi discomfort, N/V,
diarrhea,
pseudomembranous colitis,
vaginitis, rash, urticaria,
abnormal liver tests, blood
toxicity

clindamycin
neuromuscular blocking
agents BCG,
thyphoid vaccine

preg (B );
clindamycin C.difficile-associated
lincomycin diarrhea
pseudomembranous
colitis

Colchicine

colcrys (0.6 mg); flare treatment of gout: flare treatment: 6

colcine, goutichine 0.6 mg q 4-6 hr*
mg/day
prophylaxis: 0.6 mg 1-2
doses

GI discomfort, N/V,
cramping, diarrhea,
abnormal liver tests,
hepatitis, myopathy, CPK
increase, bone marrow
suppression, rash

CYP3A4 substrate

CYPinhibitor protease
inhibitors, macrolides, azole
antifungals


colchicine

colchicine;
renal/hepatic
impairment

CYP3A4

preg (C ); bone
marrow suppression
neuromuscular
toxicity

B12
macrocytic
anemia neuropathy

GI discomfort, N/V,
dizziness, drowsiness,
mydriasis, hallucination,
respiratory depression,
urinary retention,
constipation

preg (- );
MAOIs; dextromethorph
CPY2D6 inhibitor SSRIs an

15

16

preg (C );
myasthenia gravis,
coronary artery
diseases

17

Dextromethorpha romilar (15 mg, 7.5 cough suppression: 15- 120 mg/day
n
mg/5ml, 15
30 mg q 4-6 hr
mg/5ml); icolid

18

RxCU 71 /.

Diazepam

valium (2, 5, 10 mg) acute ethanol

60 mg/day
withdrawal: 5-10 mg q
6-8 hr
anxiety/ skeletal muscle
relaxant: 2-10 mg q 612 hr

amnesia, ataxia, confusion,

drowsiness, fatigue,
CNS suppressants,
paradoxical reactions, libido alcohol
changes, weakness

diazepam;
myasthenia
gravis, severe
respiratory
insufficiency

preg (D );

,
sleep apnea
syndrome, narrow
angle glaucoma

Diclofenac

voltaren (25, 50, 75, analgesic: 50 mg q8hr

100 mg); cataflam rheumatoid arthritis/
(25, 50 mg)
inflammation: 150-200
mg/day in 2-4 divided
dose

GI discomfort, N/V, PU,

bleeding, fluid retention,
edema, dizziness, headache,
hepatitis, abnormal liver
tests, Cr/BUN increased,
rash

NSAIDs;
active bleeding
disorders
major
bleeding

preg (C/D); non-active

bleeding disorders,
, nasal poly,
high risk
cardiovascular events

plain tablet
; SR tab
, enteric coated tablet
antacid,
calcium 2

Dicloxacillin

Dicloxilin (250, 500 pediatric infections <40 4000 mg/day

mg); dicloxcin,
kg: 12.5-100 mg/kg/day
diclox
divided q6hr
pediatric infections >40
kg: 125-250 mg q 6 hr
adult infections: 125500 mg q 6 hr

GI discomfort, N/V,
diarrhea, blood toxicity, PT
prolongation, bleeding,
hypersensitivity, rash,
interstitial nephritis

disulfiram probenecid
dicloxacillin; penicillins
dicloxacillin
warfarin

preg (B );

serious ADR
neuromuscular
hypersensitiviy,
electrolyte imbalance

;
1
2

19

analgesic: 150
mg/day,
inflammation: 200
mg/day

20

21

RxCU 71 /.

Digoxin

Lanoxin (250 mcg), Heart failure: 62.5-250

Lanoxin PG (62.5 mcg/day OD pc
mcg); grexin, toloxin atrial fibrillation: 125375 mcg/day OD pc

500 mcg/day; Clcr

10-50 ml/min
25-75%;
Clcr < 10 ml/min
10-25%

conduction abnormalities,
heart block, failure, shock,
dizziness, ataxia, N/V, GI
disconfort, yellow/blurred
vision, blood toxicity

potent CYP3A4 inhibitor

digoxin
;loop
diuretic thiazide
diuretics digoxin
toxicity

digoxin;
ventricular
fibrillaltion

preg (C );Digoxin

,

heart block,
hypocalcemia/
hypokalemia

drowsiness, secretion
thickened, headache,
fatigue, dizziness,
somnolence, excitement,
anticholinergics,
constipation, weakness, N/V

CNS suppressants,
alcohol;
MAOIs, anticholinergics

preg (B ); narrow
dimenhydrinate, angle glaucoma,
urinary retention
diphenhydramin
e , theophylline

S/E: bradycardia, heart

block, hypotension,
dizziness, drowsiness,
headache, insomnia, N/V,
constipation, nystagmus,
ataxia, folic depletion
ADRs: hypertrichosis,
gingival hyperplasia, blood
toxicity, hypersensitivity

phenytoin substrate
CYP2C9, 2C19
phynytoin
inducer 2B6, 2C8, 2C19,
3A4

22

Dimenhydrinate Dramamine (50

mg); denim

N/V, motion sickness, 400 mg/day

vertigo: 50-100 mg q 46 hr

Diphenylhydanto Dilantin (plain tab

in
50, ER cap 100
mg); ditoin

anticonvulsant loading
dose: 15-20 mg/kg
anticonvulsant
maintenance dose: 300
mg

23

loading dose: 2000

mg, maintenance
dose: 600 mg;

preg (D ); tube
fetal
feeding
hydantoin syndrome phenytoin
1-2

24

RxCU 71 /.

Domperidone
maleate

Motilium-M (10
mg); milax-m,
molax-m

Doxycycline

Vibracycline (100
mg); policycline

80 mg/day;
headache, migraine,
motility disorders,
N/V: 10-20 mg tid ac 15- xerostomia, abnormal liver
Scr > tests, EPS, galactorrhea
30 min
0.6 2

anticholinergics
domperidone

domperidone
anticholinergics

domperidone;
GI hemorrhage,
obstruction,
perforation,
pituitary tumor

preg (B/C );
domperidone

prolactin
galactorrhea,
gynecomastia,
amenorrhea,
impotence

motility disorders
15 ; N/V

photosensitivity, rash,
hyperpigmentation, GI
discomfort, N/V, tooth
discoloration (children),
hepatotoxicity, intracranial
hypertension

doxycycline
neuromuscular blocking
tetracycline;
agents BCG,
< 8
thyphoid vaccine;

preg (D );

30

hypotension, flushing,
tachycardia, hyperkalemia,
Scr increased, dry cough,
taste disturbance, urticaria,
angioedema

CYP3A4 inhibitor;
potassium
potassium sparing
diuretic aldosterone
antagonist

preg (C-1st trimester)/

(D-2nd,3rd trimester);
renal artery stenosis,
renal insufficiency

25

26

Enalapril

200 mg/day
pediatric (<45 kg)
infections: 2-5
mg/kg/day divided q 12
hr
adult infections: 100200 mg/day in 1-2
divided doses
Renitec (5,10,20
Heart failure: 2.5-20 80 mg/day
mg); enaril, anapril mg bid
HTN: 2.5-20 mg OD-bid

enalapril;

angioedema
ACEIs

27

RxCU 71 /.

Ethambutol

various (400, 500

mg)

TB: 15-25 mg/kg/day OD 2.5 g/day; Clcr <50

ml/min:
36-48

headache, dizziness, GI
disconfort, optic neuritis,
color blindness,
hepatotoxicity

Aluminium hydroxide

ethambutol

ethambutol;
optic nerve
disorders

preg (C ); optic

neuritis 3

Fluoxetine

Prosac (20 mg);

flulox, fluoxine

depression,
fibromyalgia, OCD,
PTSD: 20-80 mg/day
OD-bid
bulimia nervosa: 60
mg/day bid

insomnia, headache,
nervousness, abnormal
dream, libido decrease,
ejaculation abnormal, N/V,
anorexia, diarrhea

fluoxetine CYP2C9, 2D6

substrate CYP2D6
inhibitor
CNS drugs,
antipsychotics, NSAIDs,
warfarin

fluoxetine;
MAOIs,
pimozide,
thioridazine*

preg (C );

18-24 ;
serotonin syndrome
neuroleptic
malignant syndrome
triptan,
ergots, antipsychotics

Furosemide

lasix (40, 500 mg); edema, HF: 20-80 mg

various
q6-8 hr titrate to 600
mg/day
HT: 20-80 mg/day

edema, HF: 8 g/day; acute/ orthostatic

hypotension, dizziness,
oliguric state
vertigo, electrolyte
imbalance, ototoxicity,
photosensitivity, rash, blood
toxicity

aminoglycoside;
lithium

;
anuria

preg (C );

hypokalemia,
,
ototoxicity

28

80 mg/day;

compensated
cirrhosis without
ascites

29

14.00 .;
K+sparing diuretic
K+supplement

;

30

RxCU 71 /.

Glibenclamide

Daonil (5 mg);
various

type 2 DM: 2.5-20

mg/day OD-bid ac 30
min

20 mg/day; hypoglycemia, dizziness,

Clcr<50 headache, hypersensitivity
ml/min
rash, photosensitivity,
abnormal liver test, blood
toxicity

CYP2C9 inhibitor (fibric

derivatives, fluconazole,
quinolones, ranitidine)
glibenclamide

glibenclamide;
type1 DM,
DKA

preg (B/c );

sulfonamides;

hypoglycemia

30 ;


hypoglycemia

Glipizide

Minidiab (5 mg);
dipazide, glizide

type 2 DM: 2.5-15

mg/day OD

40 mg/day; edema, hypoglycemia,

Clcr<10 dizziness, headache,
ml/min
hypersensitivity rash,
photosensitivity, abnormal
liver test, blood toxicity

CYP2C9 inhibitor (fibric

derivatives, fluconazole,
quinolones, ranitidine)
glibenclamide

glibenclamide;
type1 DM,
DKA

preg (C );
sulfonamides;

hypoglycemia

30 ;


hypoglycemia

haloperidol

Haldol (5 mg);
halomed, haridol

psychosis: 0.5-5 mg po 30 mg/day

q 8-12 hr titrate up to 30
mg/day
rapid transquilization:
5-10 mg po q30-60 min

haloperidol substrate
inhibitor CYP2D6,
3A4
CNS drugs, colchicine,
ciprofloxacin, SSRIs

haloperidol;
Parkinson's
disease, coma

preg (C );
conduction
abnormality, QT
prolongation
neuroleptic malignant
syndrome

31

32

drowsiness, headache, EPS,

anticholinergic effects,
galactorrhea, gynecomastia,
sexual dysfunction,
hyperlipidemia,
hyperglycemia

33

RxCU 71 /.

Hydrochlorothiaz various (12.5, 25,

ide
50 mg)

orthostatic hypotension,
thiazide
edema: 25-100 mg/day 200 mg/day;
photosensitivity, rash,
sodium lithium
divided 1-2 doses
Clcr <40 ml/min hypokalemia, hyponatremia,
HT: 12.5-50 mg/day
hypercalcemia,
hyperuricemia, gout attack

thiazide
diuretics;
anuria, severe
renal
impairment

preg (B );

hypokalemia,
,
ototoxicity;
hyperuricemia
gout attack

14.00 .;
K+sparing diuretic
K+supplement

;

34

Hyoscine - N butylbromide

Buscopan (10 mg); GI crampimg, spasm, 80 mg/day

myspa, scopas
IBS, dyspepsia: 10-20
mg q6 hr

anticholinergic effects: dry

mouth, constipation,
tachycardia, urinary
retention, pupil dilatation,
blurred vision, photophobia,
dizziness

anticholinergics ;
domperidone

domperidone
anticholinergics

preg (B/C ); narrow

angle glaucoma,
urinary retention,
paralyitc ileus,
myasthenia gravis

Isoniazid

various (100 mg)

hepatitis, peripheral
neuropathy, rash, pellagra,
N/V, blood toxicity

CYP2C19, 2D6, 3A4

inhibitor
; alcohol
hepatotoxicity

preg (C );
-
;
pyridoxine 10-50
mg/day
neuropathy

35

36

TB: 5 mg/kg/day OD

300 mg/day

isoniazid,
active liver
disease

/
;

RxCU 71 /.

note & notices

secondary hyperuricemia chemotherapy 200-400 mg bid 3
2
active metabolite oxypurinol half-life

Tenomin 14 calenda pack (Sun, Mon, Tue, etc.)

RxCU 71 /.

amitriptyline chronic pain, post-herpetic neuralgia, IBS, post-traumatic stress disorder

time-above MIC bactericidal 3

8
infective endocarditis prophylaxis invasive American Heart
Association (AHA) 2 g 30-60 min

RxCU 71 /.

Corticosteroids ( acetazolamide) aspirin ;

Aspirin uric acid ; non-selective NSAIDs
aspirin aspirin NSAIDs 30 film-coated tablet
2 enteric-coated tablet; drug information
handbook adult dosage

azithromycin PMN cells macropharge

; azithromycin CYP3A4 inhibitor macrolides
; drug information handbook
indication-specific dosing ; immediate release capsule extended release suspension
(Zmax)

RxCU 71 /.

2-4 ;
calcium carbonate ;

time-above MIC bactericidal 4

6 -
infective endocarditis prophylaxis invasive American Heart
Association (AHA) 2 g 30-60 min

cetirizine active metabolite hydroxyzine BBB ;

RxCU 71 /.

quinolones 2
4-6 ;

RxCU 71 /.

infective endocarditis prophylaxis invasive American Heart

Association (AHA) 500 mg 30-60 min ; 14-0H metabolite parent 2

around-the-clock peak and trough variation

gout flare treatment 1 1-2

(AGREE trial) 1 3 ( 1.8 mg)
8

RxCU 71 /.

time-above MIC bactericidal 4

6 -

RxCU 71 /.

potassium digoxin
hypokalemia ; (trough
concentration) 0.5-0.8 ng/ml, >2 ng/ml

8-chlorotheophylline diphenhydramine dimenhydrinate potency

diphenhydramine dimenhydrinate 50 mg diphenhydramine 27.2 mg potency
diphenhydramine 8-chlorotheophylline
antivertigo

phenytoin zero-order
/, serum albumin ;
target total phenytoin trough level 10-20 mcg/ml; toxic >30
mcg/ml; lethal >100 mcg/ml

RxCU 71 /.

gastric emptying time

acute migraine; BBB EPS metoclopramide; prolactin

: 1x2 pc; : 1x2 pc 7 ; : ( ) 2 mg/kg/day ( ) 100 mg/day 1-2

4

RxCU 71 /.

Serious intereactions MAOIs, Pimozide Thioridazine MAOIs

14 Fluoxetine Fluoxetine 5
MAOIs ;

RxCU 71 /.

glibenclamide glyburide; glibenclamide micronized tablet conventional tablet

0.75-12 mg/day

100 mg/day 30 mg/day ADR

RxCU 71 /.

hepatitis isoniazid 3 ALT/AST upper

limit 3 / hepatitis rechallenge

RxCU 71 /.