(inhaler) budesonide 200 mcg/dose

1.
2.
3.

4.

5. lung
deposition

Giona Easyhaler
Dry Powder Inhaler (DPI)
200 doses
-
device (hand
lung coordination)
-

28.7 L/min (8)
4
(8)
- lung deposition
Pulmicort Turbuhaler (11)
- Giona Easyhaler central lung
deposition
Pulmicort
Turbuhaler systemic effects
(5)

Obucort Swinghaler
Dry Powder Inhaler (DPI)
100 doses
-
device
(hand lung
coordination)
- -

MDI
Metered Dose Inhaler (MDI)
200 doses
-
( hand lung
coordination)
- 24-84%

re-train

propellants


non-CFC

6. lubricants

propellants

Giona Easyhaler
7. Esyhaler

MDI plus
spacer 30 L/min (6)
Giona
Easyhaler

Pulmicort Turbuhaler (3,4,5,7)
8. - Easyhaler repro-ducible
(accuracy)
accuracy in dosing dose
dose MDI

- Easyhaler consis- tency in

(consistency) dosing fine particle fraction

30-60 L/min
DPI (9, 14)
9. acceptabilit Easyhaler MDI
y
MDI plus spacer (1,2)
preference
Turbuhaler

Pulmicort Turbuhaler

lubricants

propellants

epithelium
oropharynx

(12, 13)
MDI

MDI accuracy
consistency
dose

propellants

leak
valve
(14)
Easyhaler
(3, 4, 5)


device

(3,4,5)

10. dose
counter

dose
counter dose
counter

11.

Giona Easyhaler
-
lactose carrier

- bypass channel
double
dosing
- dose
Pulmicort Turbuhaler

Pulmicort Turbuhaler

MDI