Class of Drugs Drug Drug (Brand) Mechanism Therapeutic Uses Contra- ADRs Drug Interaction

(Generic) of Action indication

Non-Selective Epinephrine Binds and Bronchospasm Hyperthyroidism CNS Hyperthyroidism
Direct acting have intrinsic Anaphylactic shock Diabetes disturbance Cocaine
Natural effect on 1, Cardiac arrest Hemorrhage -blockers
Catecholamine 2,1,2 Anesthatics Cardiac
arrhythmias
Pulmonary
edema
Non-Selective Nor epinephrine Binds and Shock CNS
Direct acting have intrinsic disturbance
Natural effect on 1, Hemorrhage
Catecholamine 2,1 Cardiac
arrhythmias
Pulmonary
edema
Blenching and
sloughing of
vein at injected
site
Non-Selective Dopamine Binds and Cardiogenic and septic shock At overdose
Direct acting have intrinsic Hypotension produce same
Natural effect on 1, Severe congestive heart effect as other
Catecholamine 2,D1,D2 failure catecholamines
Non-Selective Isoproterenol Binds and To stimulate the heart in CNS
Direct acting (Isoprenaline) have intrinsic emergency conditions disturbance
Synthetic effect mainly Hemorrhage
Catecholamine on 1,2 Cardiac
arrythmias
Pulmonary
edema
Selective ( 1) Dobutamine Binds and To increase cardiac output in Increase AV
Direct acting have intrinsic aute congestive heart failure conduction
Synthetic effect 1 As well as for ionotrpic Drug Tolerance
Catecholamine support after cardiac surgery. CNS
disturbance
may develop
Hemorrhage
Cardiac
arrythmias
Pulmonary
edema
Selective 2 Cholinidine Binds and Treatment of Hypertension Lethargy
Agonist Non- have intrinsic Sedation
catecholamines effect on 2 Constipation
Xerostamia
Selective 2 - Methyldopa Binds and
Agonist Non- have intrinsic
catecholamines effect on 2
Selective 1 Phenylephrine Binds and As Nasal
Agonist Non- have intrinsic decongestant
catecholamines effect on 1 To Raise BP.
Treatment of
Paroxysmal
supraventricula
r tachycardia
Selective 2 Salbutamol Binds and Treatment of Asthma & COPD
Agonist Non- have intrinsic (short acting)
catecholamines effect on 2
Short acting
bronchodilator
Selective 2 Albuterol Binds and Treatment of Asthma & COPD Tremor Monoamine oxidase
Agonist Non- have intrinsic (short acting) Restlessness inhibitors
catecholamines effect on 2 Apprehension
Short acting Anxiety
bronchodilator
Selective 2 Terbutaline Binds and Treatment of Asthma & COPD . nervousness,
Agonist Non- have intrinsic (short acting) tremor,
catecholamines effect on 2 tachycardia,
Short acting palpitations,
bronchodilator headache,
nausea,
vomiting, and
sweating
Selective 2 Salmeterol Binds and Treatment of Asthma & COPD
Agonist Non- have intrinsic (long acting)
catecholamines effect on 2 Nocturnal asthama
long acting
bronchodilator
Selective 2 Formeterol Binds and Treatment of Asthma & COPD
Agonist Non- have intrinsic (long acting)
catecholamines effect on 2 Nocturnal asthama
long acting
bronchodilator
Indirect acting Amphetamine Release stored To treat Hyperactivity in Potential for abuse
sympathomimetic catecholamine children
agent s Narcolepsy
Appetite control
Indirect acting Cocaine Block Na+/K+ Local Anesthatic Potential for abuse
sympathomimetic ATPase pump To increase the effect of
agent inhibiting the catecholamines (given in
reuptake combination)
Indirect acting Tyramine Release stored Not clinically useful Monoamine oxidase
sympathomimetic catecholamine inhibitors
agent s
Mixed acting Ephedrine Binds and Nasal decongestant Cardiac disease Cardiac Potential for abuse
sympathomimetic have intrinsic To raise blood pressure Hypertension and CNS effects.
agent effect on , , Hyperthyroidism Tachycardia,
& Release premature
stored systoles,
catecholamine insomnia,
s nervousness,
nausea,
vomiting, and
emotional
disturbances
Mixed acting Pseudoephedrine Binds and Nasal decongestant Potential for abuse
sympathomimetic have intrinsic To raise blood pressure
agent effect on , ,
& Release
stored
catecholamine
s