Scribd Logo
Upload

Welcome to Scribd!

  • Diphenhidramin HCL

    Uploaded by

    salsa sabillah
    6 views2 pages
    The document discusses calculations for an isotonic solution and preparation of ingredients. It calculates the amount of Dipenhidramin HCl and NaCl needed for a 20ml isotonic solution based on their percentages in water. It then calculates the amounts needed for a batch of injections and weighs out the ingredients, taking 5% extra of each. The final formula given is 1% Dipenhidramin HCl, 0.623% NaCl, with water for injection to a total of 20ml.

    Original Description:

    Diphenhidramin hcl

    Original Title

    Diphenhidramin HCl

    Copyright

    © © All Rights Reserved

    Available Formats

    DOCX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document discusses calculations for an isotonic solution and preparation of ingredients. It calculates the amount of Dipenhidramin HCl and NaCl needed for a 20ml isotonic solution based on their percentages in water. It then calculates the amounts needed for a batch of injections and weighs out the ingredients, taking 5% extra of each. The final formula given is 1% Dipenhidramin HCl, 0.623% NaCl, with water for injection to a total of 20ml.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    6 views2 pages

    Diphenhidramin HCL

    Uploaded by

    salsa sabillah
    The document discusses calculations for an isotonic solution and preparation of ingredients. It calculates the amount of Dipenhidramin HCl and NaCl needed for a 20ml isotonic solution based on their percentages in water. It then calculates the amounts needed for a batch of injections and weighs out the ingredients, taking 5% extra of each. The final formula given is 1% Dipenhidramin HCl, 0.623% NaCl, with water for injection to a total of 20ml.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 2

    IV.

    Perhitungan Isotonis Larutan

    Diketahui

    C. Dipenhidramin HCl = 0,01g/1ml x 100% = 1%

    (a) = 0,161

    (b) = 0,576

    0,52 – Ʃ c.a
    W=
    b

    0,52 – Ʃ 1 x 0,161
    W= 0,576

    0,52 – 0,161 0,359


    W= = 0,576
    0,576

    W = 0,623g/100ml

    VI. Perhitungan dan Penimbangan Bahan

    a. Perhitungan Bahan

    Volume setiap vial = 5ml + 0,3ml = 5,3ml

    Volume sediaan = n x vˈ + (2 x 3)

    = 2 x 5,3ml + 6

    = 10,6ml + 6

    = 16,6ml ˷ 20ml

    1. Dipenhidramin HCl
    = 1g/100ml x 20ml = 0,2g
    2. NaCl
    = 0,623g/100ml x 20ml = 0,1246g
    3. Aqua pro injeksi ad 20ml
    b. Penimbangan Bahan
    1. Dipenhidramin HCl = 0,2g x 5% = 0,21g
    2. NaCl = 0,1246g x 5% = 0,13083g
    3. Aqua pro injeksi ad 20ml

    VII. Formula Akhir

    Dipenhidramin HCl 1%

    NaCl 0,623%

    Aqua pro injeksi ad 20ml

    You might also like