–Universal recipient Carries antigen A and B DIHYBRID CROSS TYPE O –mating of 2 different traits –Universal donor –two different parents wt 2 different traits e.g e.g a. Color of the seeds (YELLOW vs. GREEN) IA IB b. Shape of the seeds (ROUND vs. WRINKLED) SOLUTION: i IAi IBi YYRR x YYRr i IAi IBi YR YR YR YR YR Yr YR Yr
DNA- DEOXYRIBONUCLEIC ACID
YR YR YR YR –nucleic acid-macromolecule/ biomolecule YR YYRR YYRR YYRR YYRR –blueprint of life. Yr YYRr YYRr YYRr YYRr –code –coding of amino acids YR YYRR YYRR YYRR YYRR Yr YYRr YYRr YYRr YYRr 3 COMPONENTS OF AMINO ACIDS Genotype:8 YYRR & 8YYRr GR: 8:8 a. 4 NITROGENOUS BASES: Phenotype: 16 yellow round PR:16:0 PURINES NON-MENDELIAN Adenine and Guanine PYRAMIDINES –any pattern of inheritance in which traits do not Uracil/Thymineand Cytosine segregate in accordance with mendelian laws. When complementary: INCOMPLETE DOMINANCE A-T – Pattern of inheritance resuling to the blending G-C of traits When we want to duplicate DNA: –neither of the traits is dominace 1st trait = R1 R1 2nd trait= R2R2 3rd trait= R1R2 T-A e.g: C-G Black & White B1B1 x B2B2 e.g =B1B2, B1B2, B1B2, B1B DNA STRAND: GCTAATCGACGTACG CODOMINANCE COMPLIMENTARY: CGATTAGCTGCATGC –The expression of both traits e.g THYMINE TO URACIL WHEN CODING Red & White RNA: RR x WW RNA STRAND: GCU/AAU/CGA/CGU/ACG RW RW RW RW *need 3 bases to create codons- amino acid *ANTICODON- 4th process MULTIPLE ALLEILISM – Third non-mendelian patterns that contains 3 or more alleles. b. PHOSPATE GROUP –ABO Blood Groups – Compose of phosphorous Type A= IAIA or IAi c. DEOXYRIBOSE SUGAR Type B= IBIB or IBi –compose of Carbon atoms Type O= ii 3 PROCESS CENTRAL DOGMA OF which disrupt the stabilizing structures.S tructure becomes random and disorganized. MOLECULAR BIOLOGY –can also be denatured by heavy-metal ions such as Hg2+, Ag+, and Pb2+ that interact with —SH and A. REPLICATION carboxylate groups. cmost important . -Complemtary DNA strand SUBSTANCES THAT DENATURED PROTEIN: 1. Heat and ultraviolet light -Disrupt hydrogen bonds and ionic attractions by making B. TRANSCRIPTION molecules vibrate too violently; produce -codons coagulation, as in cooking an egg C. TRANSLATION 2. Organic solvents (ethanol and others -message is translated miscible with water) - Disrupt hydrogen Amino acid+amino acid bonds in proteins and probably form new =Nucleotides ones with the proteins 3. Strong acids or bases- Disrupt hydrogen MAIN CLASS SOME TYPE OF bonds and ionic attractions; prolonged SUBCLASSES REACTION exposure results in hydrolysis of protein CATALYZED 4. Detergents- Disrupt hydrogen bonds, hydrophobic interactions, and ionic Hydrolases Lipases Hydrolysis of an attractions. Nucleases ester group 5. Heavy-metal ions (Hg2+, Ag+, and Pb2+)- Proteases Hydrolysis of a Phosphate Form bonds to thiol groups and precipitate group proteins as insoluble heavy-metal salts Hydrolysis of an amide group Isomerases Epimerases Isomerization of stereocenter Ligases Carboxylases Addition of Synthesases Carbon Dioxide Formation of New bond Lyases Decarboxylases Loss of Carbon Dehydrases Dioxide Loss of Water Oxidoreductases Dehydrogenases Introduction of Oxidases double bond by Reductases removal of H2 Oxidation Reduction Ligases Kinases Transfer of a Transaminases phosphate group Transfer of an amino group
PROTEIN DENATURATION –caused when the folded native structures break down because of extreme temps. or pH values,