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    Ece Aylin Tan
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    This document summarizes monoclonal antibodies and targeted therapies used to treat cancer. It includes a diagram showing monoclonal antibodies and small molecule inhibitors targeting various pathways such as EGFR, HER2, VEGF, ALK, BRAF, MEK, ERK, mTOR, CDK4/6, PARP, immune checkpoint proteins, and TNF-alpha. The diagram lists over 50 different monoclonal antibodies and small molecule inhibitors that are used either alone or in combination to treat many cancer types.

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    This document summarizes monoclonal antibodies and targeted therapies used to treat cancer. It includes a diagram showing monoclonal antibodies and small molecule inhibitors targeting various pathways such as EGFR, HER2, VEGF, ALK, BRAF, MEK, ERK, mTOR, CDK4/6, PARP, immune checkpoint proteins, and TNF-alpha. The diagram lists over 50 different monoclonal antibodies and small molecule inhibitors that are used either alone or in combination to treat many cancer types.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    29 views1 page

    Vegfr: Y.Şahi N

    Uploaded by

    Ece Aylin Tan
    This document summarizes monoclonal antibodies and targeted therapies used to treat cancer. It includes a diagram showing monoclonal antibodies and small molecule inhibitors targeting various pathways such as EGFR, HER2, VEGF, ALK, BRAF, MEK, ERK, mTOR, CDK4/6, PARP, immune checkpoint proteins, and TNF-alpha. The diagram lists over 50 different monoclonal antibodies and small molecule inhibitors that are used either alone or in combination to treat many cancer types.

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    © All Rights Reserved
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    of 1

    Monoklonal Antikorlar tipakademisi.com Dr.

    Yavuz SAHIN

    Cetuximab
    Transtuzumab Panitumumab Bevacizumab Endotel Hücresi
    Ranibizumab
    Pertuzumab
    -
    Necitumumab Olaratumab
    Ramucirumab VEGFR P
    - - - Aflibercept
    Pegaptanib
    - Suni$nib
    Sorafenib
    Axi$nib
    Lenva$nib

    PDGFR
    EGFR
    Pazopanib
    HER2

    FGFR

    FLT3
    ALK
    Regorafenib

    JAK
    P P P P P P VEGF
    ahin
    Y.Ş .
    M.D
    - - - - - - -
    ahin
    Lapa$nib Erlo$nib Avapri$nib Pazopanib Alec$nib Pacri$nib Ruxoli$nib Y.Ş .
    Nera$nib Gefi$nib İma$nib Pemiga$nib Lestaur$nib M.D An$jen Sunan
    Ceri$nib Tofaci$nib
    Afa$nib Afa$nib Pazopanib Crizo$nib Gilteri$nib Barici$nib Hücre
    Osimer$nib Ripre$nib Entrec$nib Midostaurin Fedra$nib
    Dacomi$nib
    İdelalisib CD80
    Syk bcr abl
    RAS PI3K - Kopanlisib

    -
    Alpelisib İpilimumab
    İbru$nib Trehelimumab
    - -
    Vemurafenib
    Dabrafenib - BRAF AKT BTK - Acalabru$nib CTLA-4
    Zanubru$nib
    Fostama$nib İma$nib
    Dasa$nib
    Trame$nib
    Cobime$nib - MEK Bcl-2 - Venetoclax İmmüm Check Point
    Nilo$nib Selume$nib
    Bosu$nib ERK T Hücre
    Pona$nib PD-L1 PD1
    An$-
    Apopitozis
    Abemasiklib
    -
    SiklinD
    Palbosiklib
    Ribosiklib
    CDK4/6
    Oleparib
    - -
    DNA
    Replikasyonu
    DNA Tamiri
    PARP
    - Niraparib
    Atezolizumab Nivolumab
    Rucaparib
    Panobinostat Avelumab Pembrolizumab
    Vorinostat
    Romidepsin
    - DNA Histon
    Dease$laz Kanser Hücresi Durvalumab

    Tasarım: Dr. Yavuz ŞAHİN

    Infliximab, Adalimumab
    Certolizumab, Golimumab, - TNF-a
    ahin
    Y.Ş .D.
    CD2 - Alefacept

    -
    Etanercept M
    CD3 Muromonab, Blinatumomab (CD3-CD19)
    Anakinra, Canakininumab , Rilonacept - IL-1R
    CD4 - İbalizumab
    Daklizumab, Basailixmab, Denilökin - IL-2R
    CD11a - Efalizumab

    Dupilumab - IL-4R CD20 - Rituksimab Tositumomab, İbritumomab,


    Ofatumumab, Obinutuzumab, Okrelizumab

    Mepolizumab, Reslizumab, Benralizumab (R) - IL-5 Proteosom CD22 - Epratuzumab, inotuzumab, Moxetumomab

    Tocilizumab, Sarilumab - IL-6 - CD25


    - Basailixmab, Daclizumab
    (IL-2R)
    Lebrikizumab, Tagraxofusp - IL-13
    Bortezomib
    Karfilzomib CD30 - Brentuksimab
    İksazomib
    Brodalumab (R), Sekukinumab, İksekizumab - IL-17 CD33 - Gemtuzumab

    Ustekinumab, Guselkumab - IL-23


    CD38 - Daratumumab, Isatuximab

    CD52 - Alemtuzumab
    Efalizumab - LFA-1
    CD79 - Polatuzumab Teprotumumab

    Natalizumab - VLA-4 (a4-integrin) CD319 - Elotuzumab -


    Vedolizumab - a4b7 integrin EPCAM - Catumaksomab (CD3)
    IGF-1R
    hin
    Belimumab - BLyS Y.Şa
    M .D . TGF - Luspatersept

    Monoklonal Antikorlar tipakademisi.com Dr.Yavuz SAHIN

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